Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-01

AUTHORS

I A Wilson, J J Skehel, D C Wiley

ABSTRACT

The haemagglutinin glycoprotein of influenza virus is a trimer comprising two structurally distinct regions: a triple-stranded coiled-coil of alpha-helices extends 76 A from the membrane and a globular region of antiparallel beta-sheet, which contains the receptor binding site and the variable antigenic determinants, is positioned on top of this stem. Each subunit has an unusual loop-like topology, starting at the membrane, extending 135 A distally and folding back to enter the membrane. More... »

PAGES

366-373

Journal

TITLE

Nature

ISSUE

5796

VOLUME

289

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/289366a0

    DOI

    http://dx.doi.org/10.1038/289366a0

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7464906


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