A position effect in the control of transcription at yeast mating type loci View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-01

AUTHORS

Kim A. Nasmyth, Kelly Tatchell, Benjamin D. Hall, Caroline Astell, Michael Smith

ABSTRACT

The two mating type loci MATa and MAT alpha each produce two mRNAs that are transcribed in opposite and diverging directions from central promoters. Silent copies of MATa (HMRa) and MAT alpha (HML alpha) contain identical DNA sequences throughout the transcribed region, yet are not transcribed. It is concluded that sequences to the left of HMRa (and probably HML alpha) must somehow affect transcription initiated at the centre of each locus 700 to 1,400 base pairs away. A possible mechanism for this position effect is discussed. More... »

PAGES

244-250

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/289244a0

DOI

http://dx.doi.org/10.1038/289244a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027681242

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6256656


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