Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1980-08

AUTHORS

Martine Verhoeyen, Rongxiang Fang, Willy Min Jou, René Devos, Danny Huylebroeck, Eric Saman, Walter Fiers

ABSTRACT

A DNA copy of the gene coding for the influenza A/Aichi/2/68 haemagglutinin protein was cloned in the plasmid pBR322 and the complete nucleotide sequence determined. Comparison of this primary structure and the deduced amino acid sequence with the haemagglutinin gene and protein of strains belonging to the same (H3) subtype and to different subtypes, of both human (H2) and avian (Hav1) origin, documents further at the molecular level the two independent modes of antigenic variation of the virus--drift and shift. More... »

PAGES

771

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/286771a0

DOI

http://dx.doi.org/10.1038/286771a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031287054

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7402351


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