Ontology type: schema:ScholarlyArticle
1980-08
AUTHORSRita Anand, Richard Steeves
ABSTRACTErythroleukaemia, until now defined by morphological criteria, has been observed in mice infected with several distinct virological entities, including the polycythaemia-inducing strains of Friend virus complex (FV-P)1,2, the anaemia-inducing strains of Friend3 and Rauscher4,5 virus complex (FV-A and RV-A, respectively) and various helper-independent virus isolates derived from the FV-A6 or RV-A7 complexes. Whereas erythroleukaemia develops rapidly (within 2–3 weeks) in mice infected with any strain of FV or RV, the helper-independent virus alone is pathogenic in mice only if they are infected neonatally6,7. We now describe how two biological markers can be used to distinguish among the otherwise confusing array of virus-induced erythroleukaemias in mice. The evidence suggests that there are three different classes of this disease: (1) those (S+E+) from which both defective spleen focus-forming virus (SFFV) and erythropoietin-independent, erythroid colony forming units (CFU-EI) can be recovered, (2) those (S+E−) from which only SFFV (but not CFU-EI) can be recovered, and (3) those (S−E−) from which neither SFFV nor CFU-EI can be recovered. There is a consistent association between the type of virus used to induce the erythroleukaemia and the class of the disease induced. More... »
PAGES615-617
http://scigraph.springernature.com/pub.10.1038/286615a0
DOIhttp://dx.doi.org/10.1038/286615a0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1026411368
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/6931289
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Colony-Forming Units Assay",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Defective Viruses",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Friend murine leukemia virus",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Helper Viruses",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Leukemia, Erythroblastic, Acute",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Leukemia, Experimental",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mice",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Rauscher Virus",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Virus Replication",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Albert Einstein College of Medicine, 1300 Morris Park Avenue, 10461, Bronx, New York",
"id": "http://www.grid.ac/institutes/grid.251993.5",
"name": [
"Albert Einstein College of Medicine, 1300 Morris Park Avenue, 10461, Bronx, New York"
],
"type": "Organization"
},
"familyName": "Anand",
"givenName": "Rita",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Division of Radiation Oncology, University of Wisconsin, 600 Highland Avenue, 53792, Madison, Wisconsin",
"id": "http://www.grid.ac/institutes/grid.14003.36",
"name": [
"Albert Einstein College of Medicine, 1300 Morris Park Avenue, 10461, Bronx, New York",
"Division of Radiation Oncology, University of Wisconsin, 600 Highland Avenue, 53792, Madison, Wisconsin"
],
"type": "Organization"
},
"familyName": "Steeves",
"givenName": "Richard",
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/icb.1963.35",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027206716",
"https://doi.org/10.1038/icb.1963.35"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/2011042a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051772132",
"https://doi.org/10.1038/2011042a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/2231274a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011496759",
"https://doi.org/10.1038/2231274a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/newbio234230a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023900808",
"https://doi.org/10.1038/newbio234230a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/newbio239122a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034199675",
"https://doi.org/10.1038/newbio239122a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf01963269",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050680312",
"https://doi.org/10.1007/bf01963269"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/newbio229241a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016571401",
"https://doi.org/10.1038/newbio229241a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/256225a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041835333",
"https://doi.org/10.1038/256225a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/bjc.1966.12",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013210537",
"https://doi.org/10.1038/bjc.1966.12"
],
"type": "CreativeWork"
}
],
"datePublished": "1980-08",
"datePublishedReg": "1980-08-01",
"description": "Erythroleukaemia, until now defined by morphological criteria, has been observed in mice infected with several distinct virological entities, including the polycythaemia-inducing strains of Friend virus complex (FV-P)1,2, the anaemia-inducing strains of Friend3 and Rauscher4,5 virus complex (FV-A and RV-A, respectively) and various helper-independent virus isolates derived from the FV-A6 or RV-A7 complexes. Whereas erythroleukaemia develops rapidly (within 2\u20133 weeks) in mice infected with any strain of FV or RV, the helper-independent virus alone is pathogenic in mice only if they are infected neonatally6,7. We now describe how two biological markers can be used to distinguish among the otherwise confusing array of virus-induced erythroleukaemias in mice. The evidence suggests that there are three different classes of this disease: (1) those (S+E+) from which both defective spleen focus-forming virus (SFFV) and erythropoietin-independent, erythroid colony forming units (CFU-EI) can be recovered, (2) those (S+E\u2212) from which only SFFV (but not CFU-EI) can be recovered, and (3) those (S\u2212E\u2212) from which neither SFFV nor CFU-EI can be recovered. There is a consistent association between the type of virus used to induce the erythroleukaemia and the class of the disease induced.",
"genre": "article",
"id": "sg:pub.10.1038/286615a0",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1018957",
"issn": [
"0028-0836",
"1476-4687"
],
"name": "Nature",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "5773",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "286"
}
],
"keywords": [
"spleen focus-forming virus",
"defective spleen focus-forming virus",
"Friend virus complex",
"virus complex",
"anemia-inducing strain",
"types of viruses",
"biological markers",
"mice",
"consistent association",
"focus-forming virus",
"erythroleukaemia",
"virus isolates",
"virus",
"erythroid colonies",
"disease",
"morphological criteria",
"FV",
"RV",
"markers",
"association",
"confusing array",
"strains",
"retroviruses",
"isolates",
"evidence",
"criteria",
"entities",
"types",
"different classes",
"units",
"colonies",
"complexes",
"class",
"array"
],
"name": "How many types of erythroleukaemia are induced by retroviruses in mice?",
"pagination": "615-617",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1026411368"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/286615a0"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"6931289"
]
}
],
"sameAs": [
"https://doi.org/10.1038/286615a0",
"https://app.dimensions.ai/details/publication/pub.1026411368"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T16:50",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_177.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/286615a0"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/286615a0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/286615a0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/286615a0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/286615a0'
This table displays all metadata directly associated to this object as RDF triples.
180 TRIPLES
21 PREDICATES
79 URIs
62 LITERALS
17 BLANK NODES