Ontology type: schema:ScholarlyArticle
1980-06
AUTHORSSuzanne Cory, Jillian Jackson, Jerry M. Adams
ABSTRACTDeletions spanning portions of the heavy chain constant region (CH) locus in murine plasmacytomas are revealed by hybridization with cloned immunoglobulin DNA molecules. The pattern of deletions suggests that a lymphocyte clone switches expression of CH genes by successive deletions and that the probable CH gene order is 5′ µ-γ3-γ1-γ2b-γ2a-α3′.
PAGES450-456
http://scigraph.springernature.com/pub.10.1038/285450a0
DOIhttp://dx.doi.org/10.1038/285450a0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1050398699
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/6772957
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Genetics",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Alleles",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chromosome Deletion",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chromosome Mapping",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulin Allotypes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulin Constant Regions",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulin Heavy Chains",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulin alpha-Chains",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulin gamma-Chains",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulin mu-Chains",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoglobulins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mice",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Myeloma Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Recombination, Genetic",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, 3050, Victoria, Australia",
"id": "http://www.grid.ac/institutes/None",
"name": [
"The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, 3050, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "Cory",
"givenName": "Suzanne",
"id": "sg:person.01343253602.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343253602.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, 3050, Victoria, Australia",
"id": "http://www.grid.ac/institutes/None",
"name": [
"The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, 3050, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "Jackson",
"givenName": "Jillian",
"id": "sg:person.0633023453.46",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633023453.46"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, 3050, Victoria, Australia",
"id": "http://www.grid.ac/institutes/None",
"name": [
"The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, 3050, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "Adams",
"givenName": "Jerry M.",
"id": "sg:person.014441722212.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014441722212.92"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/280288a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052104343",
"https://doi.org/10.1038/280288a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/227341a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005980030",
"https://doi.org/10.1038/227341a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf01564089",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014900678",
"https://doi.org/10.1007/bf01564089"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/275291a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012827819",
"https://doi.org/10.1038/275291a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/276790a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033395984",
"https://doi.org/10.1038/276790a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/267709a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018132778",
"https://doi.org/10.1038/267709a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/277627a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003581176",
"https://doi.org/10.1038/277627a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/283351a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023896040",
"https://doi.org/10.1038/283351a0"
],
"type": "CreativeWork"
}
],
"datePublished": "1980-06",
"datePublishedReg": "1980-06-01",
"description": "Deletions spanning portions of the heavy chain constant region (CH) locus in murine plasmacytomas are revealed by hybridization with cloned immunoglobulin DNA molecules. The pattern of deletions suggests that a lymphocyte clone switches expression of CH genes by successive deletions and that the probable CH gene order is 5\u2032 \u00b5-\u03b33-\u03b31-\u03b32b-\u03b32a-\u03b13\u2032.",
"genre": "article",
"id": "sg:pub.10.1038/285450a0",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1018957",
"issn": [
"0028-0836",
"1476-4687"
],
"name": "Nature",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "5765",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "285"
}
],
"keywords": [
"constant region locus",
"region locus",
"gene order",
"CH genes",
"pattern of deletions",
"immunoglobulin heavy chain expression",
"DNA molecules",
"successive deletions",
"murine plasmacytomas",
"deletion",
"heavy chain expression",
"loci",
"expression",
"chain expression",
"genes",
"clones",
"hybridization",
"lymphocyte clones",
"molecules",
"switch",
"patterns",
"portion",
"plasmacytoma",
"order"
],
"name": "Deletions in the constant region locus can account for switches in immunoglobulin heavy chain expression",
"pagination": "450-456",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1050398699"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/285450a0"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"6772957"
]
}
],
"sameAs": [
"https://doi.org/10.1038/285450a0",
"https://app.dimensions.ai/details/publication/pub.1050398699"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:17",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_173.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/285450a0"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/285450a0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/285450a0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/285450a0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/285450a0'
This table displays all metadata directly associated to this object as RDF triples.
192 TRIPLES
22 PREDICATES
74 URIs
58 LITERALS
22 BLANK NODES