Satellite DNA is transcribed on lampbrush chromosomes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1980-02

AUTHORS

Jennifer M. Varley, Herbert C. Macgregor, Harry P. Erba

ABSTRACT

During the lampbrush stage of oogenesis there is widespread transcription, and it has been estimated that the total amount of DNA transcribed may be an order of magnitude greater than that required to produce the necessary functional RNA for the oocyte1. We therefore considered it likely that some of the transcribed sequences have little, if any, translational significance, and may include both middle repetitive2 and highly repeated, or satellite, sequences. Satellite DNA is generally defined as rapidly reannealing DNA which has a short basic sequence that is repeated millions of times in the genome, usually in tandem arrays3,4. The short repeated length, coupled with the organisation of satellite sequences in high order molecular weight tandem arrays in heterochromatic regions, have been put forward as reasons for supposing that this type of DNA is not normally transcribed5. We report here that we have looked for and found evidence of transcription of satellite DNA on lampbrush loops in oocytes of the crested newt, Triturus cristatus carnifex. More... »

PAGES

686-688

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/283686a0

DOI

http://dx.doi.org/10.1038/283686a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052377617

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7188786


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