The molecular structure of lecithin dihydrate View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1979-10

AUTHORS

Robert H. Pearson, Irmin Pascher

ABSTRACT

Lecithin is a major structural component of biological membranes. Because of their amphipathic nature, lecithin and related phospholipids tend to aggregate as bilayer structures in which the hydrophilic head groups are orientated towards the surface and the hydrophobic hydrocarbon chains towards the interior. A detailed knowledge of the three-dimensional structure of lecithins will aid in the understanding of their role in membrane structure and function, but is still lacking. To this end we have now crystallised and solved the molecular structure of 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine (DMPC), a lecithin species in the naturally occurring configuration. This compound crystallises from a water-containing solution, with two water molecules (5% w/w) of hydration. More... »

PAGES

499-501

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/281499a0

DOI

http://dx.doi.org/10.1038/281499a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041411561

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/492310


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