Interferon action may be mediated by activation of a nuclease by pppA2′p5′A2′p5′A View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1978-06

AUTHORS

CORRADO BAGLIONI, MICHAEL A. MINKS, PATRICIA A. MARONEY

ABSTRACT

EXPOSURE of cells to the antiviral agent interferon inhibits virus replication1. In interferon-treated cells the adsorption, penetration and uncoating of infecting viruses is not affected, but the synthesis of virus-specific mRNA and viral proteins is inhibited2,3. We have studied a mechanism for degradation of mRNA which may be activated in interferon-treated cells by the presence of double-stranded RNA (dsRNA) of viral origin. Lengyel et al. have reported that an endonuclease present in extracts of cells treated with interferon is activated by dsRNA and ATP4–6. The endonuclease degrades mRNA by a process which can be divided into two phases: an activation phase requiring the presence of both ATP and dsRNA but not of mRNA, and an endonucleolytic phase, which does not require either ATP or dsRNA6. Kerr et al. have at the same time reported that protein synthesis is inhibited in extracts of cells treated with interferon after incubation with dsRNA and ATP7. In these incubation conditions a low molecular weight inhibitor is formed from ATP8,9. The mechanism of action of this inhibitor, the structure of which has recently been determined as pppA2′p5′A2′p5′A (pppApApA)10, is not known. Our results indicate that this trinucleotide mediates the activation of a nuclease which degrades mRNA and may therefore inhibit protein synthesis in this way. More... »

PAGES

684-687

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/273684a0

DOI

http://dx.doi.org/10.1038/273684a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052939005

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/208001


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenine Nucleotides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endonucleases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enzyme Activation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exonucleases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HeLa Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interferons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligonucleotides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligoribonucleotides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polyribosomes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ribonucleases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vesicular stomatitis Indiana virus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York", 
          "id": "http://www.grid.ac/institutes/grid.265850.c", 
          "name": [
            "Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "BAGLIONI", 
        "givenName": "CORRADO", 
        "id": "sg:person.0614171505.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614171505.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York", 
          "id": "http://www.grid.ac/institutes/grid.265850.c", 
          "name": [
            "Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "MINKS", 
        "givenName": "MICHAEL A.", 
        "id": "sg:person.01223347205.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223347205.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York", 
          "id": "http://www.grid.ac/institutes/grid.265850.c", 
          "name": [
            "Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "MARONEY", 
        "givenName": "PATRICIA A.", 
        "id": "sg:person.01337575605.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337575605.29"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/264477a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000145825", 
          "https://doi.org/10.1038/264477a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/261291a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030940534", 
          "https://doi.org/10.1038/261291a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/268537a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014596186", 
          "https://doi.org/10.1038/268537a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/250057a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047096607", 
          "https://doi.org/10.1038/250057a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/264370a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026245557", 
          "https://doi.org/10.1038/264370a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/266235a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001930109", 
          "https://doi.org/10.1038/266235a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1978-06", 
    "datePublishedReg": "1978-06-01", 
    "description": "EXPOSURE of cells to the antiviral agent interferon inhibits virus replication1. In interferon-treated cells the adsorption, penetration and uncoating of infecting viruses is not affected, but the synthesis of virus-specific mRNA and viral proteins is inhibited2,3. We have studied a mechanism for degradation of mRNA which may be activated in interferon-treated cells by the presence of double-stranded RNA (dsRNA) of viral origin. Lengyel et al. have reported that an endonuclease present in extracts of cells treated with interferon is activated by dsRNA and ATP4\u20136. The endonuclease degrades mRNA by a process which can be divided into two phases: an activation phase requiring the presence of both ATP and dsRNA but not of mRNA, and an endonucleolytic phase, which does not require either ATP or dsRNA6. Kerr et al. have at the same time reported that protein synthesis is inhibited in extracts of cells treated with interferon after incubation with dsRNA and ATP7. In these incubation conditions a low molecular weight inhibitor is formed from ATP8,9. The mechanism of action of this inhibitor, the structure of which has recently been determined as pppA2\u2032p5\u2032A2\u2032p5\u2032A (pppApApA)10, is not known. Our results indicate that this trinucleotide mediates the activation of a nuclease which degrades mRNA and may therefore inhibit protein synthesis in this way.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/273684a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5664", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "273"
      }
    ], 
    "keywords": [
      "interferon-treated cells", 
      "antiviral agent interferon", 
      "mechanism of action", 
      "low molecular weight inhibitors", 
      "exposure of cells", 
      "interferon", 
      "protein synthesis", 
      "extracts of cells", 
      "viral proteins", 
      "virus-specific mRNA", 
      "viral origin", 
      "interferon action", 
      "weight inhibitors", 
      "mRNA", 
      "activation phase", 
      "cells", 
      "inhibitors", 
      "activation", 
      "dsRNA", 
      "extract", 
      "virus", 
      "ATP", 
      "action", 
      "exposure", 
      "incubation conditions", 
      "uncoating", 
      "presence", 
      "mechanism", 
      "incubation", 
      "RNA", 
      "protein", 
      "degradation of mRNA", 
      "ATP7", 
      "synthesis", 
      "time", 
      "present", 
      "origin", 
      "penetration", 
      "phase", 
      "results", 
      "same time", 
      "conditions", 
      "nuclease", 
      "endonuclease", 
      "replication1", 
      "trinucleotide", 
      "degradation", 
      "process", 
      "way", 
      "structure", 
      "adsorption", 
      "agent interferon", 
      "virus replication1", 
      "endonuclease present", 
      "ATP4\u20136", 
      "endonucleolytic phase", 
      "dsRNA6", 
      "molecular weight inhibitor", 
      "pppA2\u2032p5\u2032A2\u2032p5\u2032A"
    ], 
    "name": "Interferon action may be mediated by activation of a nuclease by pppA2\u2032p5\u2032A2\u2032p5\u2032A", 
    "pagination": "684-687", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1052939005"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/273684a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "208001"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/273684a0", 
      "https://app.dimensions.ai/details/publication/pub.1052939005"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_124.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/273684a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/273684a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/273684a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/273684a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/273684a0'


 

This table displays all metadata directly associated to this object as RDF triples.

210 TRIPLES      21 PREDICATES      104 URIs      90 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/273684a0 schema:about N126daf2cb99d419c968ed45cc6b6adc6
2 N17cfb3540e724e26a97789681cb2c2b2
3 N1db2bc7914e04add848be6a3bff49cb6
4 N5a61213ce6e74e419ca08aaa2a5bfe29
5 N774035bcaef7402d8bfee3a08702b1c1
6 N9be4ab576893487b88f5d1b41a9ae1b4
7 Nb899183355c846418c7c4147145c98a7
8 Nbe2efdbfa5e64ff19a60609eb7f5a036
9 Nbe4c164286164981aa6b882e24fc27c8
10 Nc014bbf846e0488bbb190c86d9d81703
11 Nc6522f5beddc431387c8505afba8c7d1
12 Nd9297a457e8d43a0a9ba7b85c123d18c
13 Ne8052e50f13f4ceda6f2a9d6cd80091d
14 anzsrc-for:11
15 anzsrc-for:1108
16 schema:author Na47f705da1ae48b9bf31022006fd9813
17 schema:citation sg:pub.10.1038/250057a0
18 sg:pub.10.1038/261291a0
19 sg:pub.10.1038/264370a0
20 sg:pub.10.1038/264477a0
21 sg:pub.10.1038/266235a0
22 sg:pub.10.1038/268537a0
23 schema:datePublished 1978-06
24 schema:datePublishedReg 1978-06-01
25 schema:description EXPOSURE of cells to the antiviral agent interferon inhibits virus replication1. In interferon-treated cells the adsorption, penetration and uncoating of infecting viruses is not affected, but the synthesis of virus-specific mRNA and viral proteins is inhibited2,3. We have studied a mechanism for degradation of mRNA which may be activated in interferon-treated cells by the presence of double-stranded RNA (dsRNA) of viral origin. Lengyel et al. have reported that an endonuclease present in extracts of cells treated with interferon is activated by dsRNA and ATP4–6. The endonuclease degrades mRNA by a process which can be divided into two phases: an activation phase requiring the presence of both ATP and dsRNA but not of mRNA, and an endonucleolytic phase, which does not require either ATP or dsRNA6. Kerr et al. have at the same time reported that protein synthesis is inhibited in extracts of cells treated with interferon after incubation with dsRNA and ATP7. In these incubation conditions a low molecular weight inhibitor is formed from ATP8,9. The mechanism of action of this inhibitor, the structure of which has recently been determined as pppA2′p5′A2′p5′A (pppApApA)10, is not known. Our results indicate that this trinucleotide mediates the activation of a nuclease which degrades mRNA and may therefore inhibit protein synthesis in this way.
26 schema:genre article
27 schema:isAccessibleForFree false
28 schema:isPartOf N8d3d8c72e327489d91e131f9892064d1
29 Nb146a28898e742798a023ccbab3fd63b
30 sg:journal.1018957
31 schema:keywords ATP
32 ATP4–6
33 ATP7
34 RNA
35 action
36 activation
37 activation phase
38 adsorption
39 agent interferon
40 antiviral agent interferon
41 cells
42 conditions
43 degradation
44 degradation of mRNA
45 dsRNA
46 dsRNA6
47 endonuclease
48 endonuclease present
49 endonucleolytic phase
50 exposure
51 exposure of cells
52 extract
53 extracts of cells
54 incubation
55 incubation conditions
56 inhibitors
57 interferon
58 interferon action
59 interferon-treated cells
60 low molecular weight inhibitors
61 mRNA
62 mechanism
63 mechanism of action
64 molecular weight inhibitor
65 nuclease
66 origin
67 penetration
68 phase
69 pppA2′p5′A2′p5′A
70 presence
71 present
72 process
73 protein
74 protein synthesis
75 replication1
76 results
77 same time
78 structure
79 synthesis
80 time
81 trinucleotide
82 uncoating
83 viral origin
84 viral proteins
85 virus
86 virus replication1
87 virus-specific mRNA
88 way
89 weight inhibitors
90 schema:name Interferon action may be mediated by activation of a nuclease by pppA2′p5′A2′p5′A
91 schema:pagination 684-687
92 schema:productId N4f19770e710848e4be02f2433f18e513
93 Na30a52ce0d1d4464b774dc18b2f1b8c3
94 Nb7675f88ac5f4b17b202669a0c50fce3
95 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052939005
96 https://doi.org/10.1038/273684a0
97 schema:sdDatePublished 2022-01-01T18:00
98 schema:sdLicense https://scigraph.springernature.com/explorer/license/
99 schema:sdPublisher N5b6c575dac034513ae902cc0d39d73fe
100 schema:url https://doi.org/10.1038/273684a0
101 sgo:license sg:explorer/license/
102 sgo:sdDataset articles
103 rdf:type schema:ScholarlyArticle
104 N126daf2cb99d419c968ed45cc6b6adc6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Oligonucleotides
106 rdf:type schema:DefinedTerm
107 N17cfb3540e724e26a97789681cb2c2b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Enzyme Activation
109 rdf:type schema:DefinedTerm
110 N1db2bc7914e04add848be6a3bff49cb6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Endonucleases
112 rdf:type schema:DefinedTerm
113 N4f19770e710848e4be02f2433f18e513 schema:name doi
114 schema:value 10.1038/273684a0
115 rdf:type schema:PropertyValue
116 N5a61213ce6e74e419ca08aaa2a5bfe29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Ribonucleases
118 rdf:type schema:DefinedTerm
119 N5b6c575dac034513ae902cc0d39d73fe schema:name Springer Nature - SN SciGraph project
120 rdf:type schema:Organization
121 N774035bcaef7402d8bfee3a08702b1c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Interferons
123 rdf:type schema:DefinedTerm
124 N8d3d8c72e327489d91e131f9892064d1 schema:volumeNumber 273
125 rdf:type schema:PublicationVolume
126 N9be4ab576893487b88f5d1b41a9ae1b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Oligoribonucleotides
128 rdf:type schema:DefinedTerm
129 Na30a52ce0d1d4464b774dc18b2f1b8c3 schema:name pubmed_id
130 schema:value 208001
131 rdf:type schema:PropertyValue
132 Na47f705da1ae48b9bf31022006fd9813 rdf:first sg:person.0614171505.33
133 rdf:rest Ncf57b5e4f6f7401d9a8934d7a2457d49
134 Nb146a28898e742798a023ccbab3fd63b schema:issueNumber 5664
135 rdf:type schema:PublicationIssue
136 Nb7675f88ac5f4b17b202669a0c50fce3 schema:name dimensions_id
137 schema:value pub.1052939005
138 rdf:type schema:PropertyValue
139 Nb899183355c846418c7c4147145c98a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Vesicular stomatitis Indiana virus
141 rdf:type schema:DefinedTerm
142 Nbe2efdbfa5e64ff19a60609eb7f5a036 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Exonucleases
144 rdf:type schema:DefinedTerm
145 Nbe4c164286164981aa6b882e24fc27c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Adenine Nucleotides
147 rdf:type schema:DefinedTerm
148 Nc014bbf846e0488bbb190c86d9d81703 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Polyribosomes
150 rdf:type schema:DefinedTerm
151 Nc6522f5beddc431387c8505afba8c7d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name RNA, Messenger
153 rdf:type schema:DefinedTerm
154 Ncf57b5e4f6f7401d9a8934d7a2457d49 rdf:first sg:person.01223347205.54
155 rdf:rest Nf1d221ab2c584dfc9990d655753091e6
156 Nd9297a457e8d43a0a9ba7b85c123d18c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name HeLa Cells
158 rdf:type schema:DefinedTerm
159 Ne8052e50f13f4ceda6f2a9d6cd80091d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name RNA, Viral
161 rdf:type schema:DefinedTerm
162 Nf1d221ab2c584dfc9990d655753091e6 rdf:first sg:person.01337575605.29
163 rdf:rest rdf:nil
164 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
165 schema:name Medical and Health Sciences
166 rdf:type schema:DefinedTerm
167 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
168 schema:name Medical Microbiology
169 rdf:type schema:DefinedTerm
170 sg:journal.1018957 schema:issn 0028-0836
171 1476-4687
172 schema:name Nature
173 schema:publisher Springer Nature
174 rdf:type schema:Periodical
175 sg:person.01223347205.54 schema:affiliation grid-institutes:grid.265850.c
176 schema:familyName MINKS
177 schema:givenName MICHAEL A.
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223347205.54
179 rdf:type schema:Person
180 sg:person.01337575605.29 schema:affiliation grid-institutes:grid.265850.c
181 schema:familyName MARONEY
182 schema:givenName PATRICIA A.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337575605.29
184 rdf:type schema:Person
185 sg:person.0614171505.33 schema:affiliation grid-institutes:grid.265850.c
186 schema:familyName BAGLIONI
187 schema:givenName CORRADO
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614171505.33
189 rdf:type schema:Person
190 sg:pub.10.1038/250057a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047096607
191 https://doi.org/10.1038/250057a0
192 rdf:type schema:CreativeWork
193 sg:pub.10.1038/261291a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030940534
194 https://doi.org/10.1038/261291a0
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/264370a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026245557
197 https://doi.org/10.1038/264370a0
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/264477a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000145825
200 https://doi.org/10.1038/264477a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/266235a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001930109
203 https://doi.org/10.1038/266235a0
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/268537a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014596186
206 https://doi.org/10.1038/268537a0
207 rdf:type schema:CreativeWork
208 grid-institutes:grid.265850.c schema:alternateName Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York
209 schema:name Department of Biological Sciences, State University of New York at Albany, 12222, Albany, New York
210 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...