Unequal crossing over at the rRNA locus as a source of quantitative genetic variation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1978-03

AUTHORS

D. A. BRISCOE, R. FRANKHAM, R. K. NURTHEN

ABSTRACT

MUTATIONS, in the broad sense, are the source of genetic variation for evolutionary change, whether through the agency of natural or artificial selection. The contributions of new mutations to genetic variation in artificial selection lines are thought to be small, as estimates of the rate of generation of new genetic variation by mutation have been only of the order of 10−3 times the environmental variance for the character per generation1. However, several occurrences in selection lines2,3 have led us to question this view. We set out to measure the contribution of ‘mutations’ (from whatever source) to selection response for a quantitative character by selecting in lines from a largely homozygous base stock of Drosophila melanogaster. In two of the low lines response due to bobbed alleles was detected. This has allowed us to implicate unequal crossing over as a source of quantitative genetic variation and to question current views concerning the rate at which new genetic variation arises. More... »

PAGES

80

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/272080a0

DOI

http://dx.doi.org/10.1038/272080a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013824519

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/415250


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crossing Over, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drosophila melanogaster", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Linkage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Variation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Ribosomal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Selection, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "X Chromosome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "BRISCOE", 
        "givenName": "D. A.", 
        "id": "sg:person.01167354714.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167354714.36"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "FRANKHAM", 
        "givenName": "R.", 
        "id": "sg:person.01253132112.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253132112.55"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "NURTHEN", 
        "givenName": "R. K.", 
        "id": "sg:person.015043670274.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015043670274.12"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02981621", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012962850", 
          "https://doi.org/10.1007/bf02981621"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02981621", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012962850", 
          "https://doi.org/10.1007/bf02981621"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00328865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015641727", 
          "https://doi.org/10.1007/bf00328865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00577100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021140608", 
          "https://doi.org/10.1007/bf00577100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.ge.09.120175.002035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042011938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/hdy.1976.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042525505", 
          "https://doi.org/10.1038/hdy.1976.8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/hdy.1976.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042525505", 
          "https://doi.org/10.1038/hdy.1976.8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2271108a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044235569", 
          "https://doi.org/10.1038/2271108a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00484920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049843010", 
          "https://doi.org/10.1007/bf00484920"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00484920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049843010", 
          "https://doi.org/10.1007/bf00484920"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/hdy.1975.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052591837", 
          "https://doi.org/10.1038/hdy.1975.74"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/hdy.1975.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052591837", 
          "https://doi.org/10.1038/hdy.1975.74"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0016672300016037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053791538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0016672300016037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053791538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077358702", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081021930", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082783967", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1978-03", 
    "datePublishedReg": "1978-03-01", 
    "description": "MUTATIONS, in the broad sense, are the source of genetic variation for evolutionary change, whether through the agency of natural or artificial selection. The contributions of new mutations to genetic variation in artificial selection lines are thought to be small, as estimates of the rate of generation of new genetic variation by mutation have been only of the order of 10\u22123 times the environmental variance for the character per generation1. However, several occurrences in selection lines2,3 have led us to question this view. We set out to measure the contribution of \u2018mutations\u2019 (from whatever source) to selection response for a quantitative character by selecting in lines from a largely homozygous base stock of Drosophila melanogaster. In two of the low lines response due to bobbed alleles was detected. This has allowed us to implicate unequal crossing over as a source of quantitative genetic variation and to question current views concerning the rate at which new genetic variation arises.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/272080a0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5648", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "272"
      }
    ], 
    "name": "Unequal crossing over at the rRNA locus as a source of quantitative genetic variation", 
    "pagination": "80", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "41db41a6ec0e1226c067d6b6f956d6967ffbf9c830e20589dafe766c6f6881e1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "415250"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/272080a0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013824519"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/272080a0", 
      "https://app.dimensions.ai/details/publication/pub.1013824519"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T23:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000422.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/272080a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/272080a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/272080a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/272080a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/272080a0'


 

This table displays all metadata directly associated to this object as RDF triples.

169 TRIPLES      21 PREDICATES      54 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/272080a0 schema:about N207038127fc9484889597e50c9395d41
2 N226443de129a4472b32b95bfbd45decb
3 N38850661b2c44e14a9a2a76296feb4a0
4 N9730f4edee91481ba15d174d5be57d2c
5 Nb048a3211a1544ad9ecfc23510d82cc9
6 Nd273f9d296694de7bd7018b7c23f6a69
7 Nd27d0c1c3755496c83b66936a8e2017b
8 Nd430a7582ab64df795f80a16fbaa77e7
9 Ndb02c4ad04094f8083ec751760152977
10 Nea92220c359947afbf8435d66cffbb7d
11 Neb98fe1a558c42c4817260e599933f08
12 Nf30f75e837a04e77b01cb1033d706ae8
13 Nfd9e01be5b1c4b5688240e8c0ace1a6b
14 anzsrc-for:06
15 anzsrc-for:0604
16 schema:author N1d02940c228646d98a6e5a11dad80f49
17 schema:citation sg:pub.10.1007/bf00328865
18 sg:pub.10.1007/bf00484920
19 sg:pub.10.1007/bf00577100
20 sg:pub.10.1007/bf02981621
21 sg:pub.10.1038/2271108a0
22 sg:pub.10.1038/hdy.1975.74
23 sg:pub.10.1038/hdy.1976.8
24 https://app.dimensions.ai/details/publication/pub.1077358702
25 https://app.dimensions.ai/details/publication/pub.1081021930
26 https://app.dimensions.ai/details/publication/pub.1082783967
27 https://doi.org/10.1017/s0016672300016037
28 https://doi.org/10.1146/annurev.ge.09.120175.002035
29 schema:datePublished 1978-03
30 schema:datePublishedReg 1978-03-01
31 schema:description MUTATIONS, in the broad sense, are the source of genetic variation for evolutionary change, whether through the agency of natural or artificial selection. The contributions of new mutations to genetic variation in artificial selection lines are thought to be small, as estimates of the rate of generation of new genetic variation by mutation have been only of the order of 10−3 times the environmental variance for the character per generation1. However, several occurrences in selection lines2,3 have led us to question this view. We set out to measure the contribution of ‘mutations’ (from whatever source) to selection response for a quantitative character by selecting in lines from a largely homozygous base stock of Drosophila melanogaster. In two of the low lines response due to bobbed alleles was detected. This has allowed us to implicate unequal crossing over as a source of quantitative genetic variation and to question current views concerning the rate at which new genetic variation arises.
32 schema:genre research_article
33 schema:inLanguage en
34 schema:isAccessibleForFree false
35 schema:isPartOf N656722446b8e4999b645f271050662dd
36 N71f02eee817c4f99b790bb6e50cfccb2
37 sg:journal.1018957
38 schema:name Unequal crossing over at the rRNA locus as a source of quantitative genetic variation
39 schema:pagination 80
40 schema:productId N55ee406dda094c5da75bdae3c726a080
41 N5a0648abd5454899b82a5c7480c2fc22
42 N65a982eb0caa4b159f296a4fdfa747dc
43 Nc364daf168d5464796949ab0cb59b7a5
44 Nfb4ba7b4c8964298a9f2930a497148fa
45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013824519
46 https://doi.org/10.1038/272080a0
47 schema:sdDatePublished 2019-04-10T23:11
48 schema:sdLicense https://scigraph.springernature.com/explorer/license/
49 schema:sdPublisher N0be619c8f8864c39a629753c52aee675
50 schema:url https://www.nature.com/articles/272080a0
51 sgo:license sg:explorer/license/
52 sgo:sdDataset articles
53 rdf:type schema:ScholarlyArticle
54 N0be619c8f8864c39a629753c52aee675 schema:name Springer Nature - SN SciGraph project
55 rdf:type schema:Organization
56 N1d02940c228646d98a6e5a11dad80f49 rdf:first sg:person.01167354714.36
57 rdf:rest Naf59381093954f8abca5278b12675387
58 N207038127fc9484889597e50c9395d41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
59 schema:name Genetic Linkage
60 rdf:type schema:DefinedTerm
61 N226443de129a4472b32b95bfbd45decb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Female
63 rdf:type schema:DefinedTerm
64 N38850661b2c44e14a9a2a76296feb4a0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Crossing Over, Genetic
66 rdf:type schema:DefinedTerm
67 N4fa48a6b954c4bf48a9b42765832e169 rdf:first sg:person.015043670274.12
68 rdf:rest rdf:nil
69 N55ee406dda094c5da75bdae3c726a080 schema:name doi
70 schema:value 10.1038/272080a0
71 rdf:type schema:PropertyValue
72 N5a0648abd5454899b82a5c7480c2fc22 schema:name pubmed_id
73 schema:value 415250
74 rdf:type schema:PropertyValue
75 N656722446b8e4999b645f271050662dd schema:issueNumber 5648
76 rdf:type schema:PublicationIssue
77 N65a982eb0caa4b159f296a4fdfa747dc schema:name dimensions_id
78 schema:value pub.1013824519
79 rdf:type schema:PropertyValue
80 N71f02eee817c4f99b790bb6e50cfccb2 schema:volumeNumber 272
81 rdf:type schema:PublicationVolume
82 N9730f4edee91481ba15d174d5be57d2c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Drosophila melanogaster
84 rdf:type schema:DefinedTerm
85 Naf59381093954f8abca5278b12675387 rdf:first sg:person.01253132112.55
86 rdf:rest N4fa48a6b954c4bf48a9b42765832e169
87 Nb048a3211a1544ad9ecfc23510d82cc9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Sex Ratio
89 rdf:type schema:DefinedTerm
90 Nc364daf168d5464796949ab0cb59b7a5 schema:name nlm_unique_id
91 schema:value 0410462
92 rdf:type schema:PropertyValue
93 Nd273f9d296694de7bd7018b7c23f6a69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Selection, Genetic
95 rdf:type schema:DefinedTerm
96 Nd27d0c1c3755496c83b66936a8e2017b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Genetic Variation
98 rdf:type schema:DefinedTerm
99 Nd430a7582ab64df795f80a16fbaa77e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Mutation
101 rdf:type schema:DefinedTerm
102 Ndb02c4ad04094f8083ec751760152977 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Male
104 rdf:type schema:DefinedTerm
105 Nea92220c359947afbf8435d66cffbb7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name X Chromosome
107 rdf:type schema:DefinedTerm
108 Neb98fe1a558c42c4817260e599933f08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Animals
110 rdf:type schema:DefinedTerm
111 Nf30f75e837a04e77b01cb1033d706ae8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name RNA, Ribosomal
113 rdf:type schema:DefinedTerm
114 Nfb4ba7b4c8964298a9f2930a497148fa schema:name readcube_id
115 schema:value 41db41a6ec0e1226c067d6b6f956d6967ffbf9c830e20589dafe766c6f6881e1
116 rdf:type schema:PropertyValue
117 Nfd9e01be5b1c4b5688240e8c0ace1a6b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Genes
119 rdf:type schema:DefinedTerm
120 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
121 schema:name Biological Sciences
122 rdf:type schema:DefinedTerm
123 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
124 schema:name Genetics
125 rdf:type schema:DefinedTerm
126 sg:journal.1018957 schema:issn 0090-0028
127 1476-4687
128 schema:name Nature
129 rdf:type schema:Periodical
130 sg:person.01167354714.36 schema:familyName BRISCOE
131 schema:givenName D. A.
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167354714.36
133 rdf:type schema:Person
134 sg:person.01253132112.55 schema:familyName FRANKHAM
135 schema:givenName R.
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253132112.55
137 rdf:type schema:Person
138 sg:person.015043670274.12 schema:familyName NURTHEN
139 schema:givenName R. K.
140 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015043670274.12
141 rdf:type schema:Person
142 sg:pub.10.1007/bf00328865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015641727
143 https://doi.org/10.1007/bf00328865
144 rdf:type schema:CreativeWork
145 sg:pub.10.1007/bf00484920 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049843010
146 https://doi.org/10.1007/bf00484920
147 rdf:type schema:CreativeWork
148 sg:pub.10.1007/bf00577100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021140608
149 https://doi.org/10.1007/bf00577100
150 rdf:type schema:CreativeWork
151 sg:pub.10.1007/bf02981621 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012962850
152 https://doi.org/10.1007/bf02981621
153 rdf:type schema:CreativeWork
154 sg:pub.10.1038/2271108a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044235569
155 https://doi.org/10.1038/2271108a0
156 rdf:type schema:CreativeWork
157 sg:pub.10.1038/hdy.1975.74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052591837
158 https://doi.org/10.1038/hdy.1975.74
159 rdf:type schema:CreativeWork
160 sg:pub.10.1038/hdy.1976.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042525505
161 https://doi.org/10.1038/hdy.1976.8
162 rdf:type schema:CreativeWork
163 https://app.dimensions.ai/details/publication/pub.1077358702 schema:CreativeWork
164 https://app.dimensions.ai/details/publication/pub.1081021930 schema:CreativeWork
165 https://app.dimensions.ai/details/publication/pub.1082783967 schema:CreativeWork
166 https://doi.org/10.1017/s0016672300016037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053791538
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1146/annurev.ge.09.120175.002035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042011938
169 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...