Structure of nucleosome core particles of chromatin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1977-09-01

AUTHORS

J. T. Finch, L. C. Lutter, D. Rhodes, R. S. Brown, B. Rushton, M. Levitt, A. Klug

ABSTRACT

Crystals have been obtained of nucleosome cores and analysed by X-ray diffraction and electron microscopy. The core is a flat particle of dimensions about 110 × 110 × 57 Å, somewhat wedge shaped, and strongly divided into two ‘layers’, consistent with the DNA being wound into about 1¾ turns of a fiat superhelix of a pitch about 28 Å. The organisation of the DNA can be correlated with the results of enzyme digestion studies. A change in the screw of the DNA double helix on nucleosome formation can be deduced. More... »

PAGES

29-36

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/269029a0

DOI

http://dx.doi.org/10.1038/269029a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017162562

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/895884


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