3′ Non-coding region sequences in eukaryotic messenger RNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1976-09

AUTHORS

N. J. Proudfoot, G. G. Brownlee

ABSTRACT

The sequence A–A–U–A–A–A is present in six different purified messenger RNA molecules (specifically the α- and β-globulin mRNAs of rabbit and human, the immunoglobulin light chain mRN A of mouse (MOPC 21) and the ovalbumin mRN A of chicken) about 20 residues away from the 3′-terminal poly(A) sequence. In addition, a large selection of the 3′ non-coding regions of rabbit and human globin mRN As (both the α- and β- globin mRN As) are 85% homologous, demonstrating that this region is significantly conserved in evolution. More... »

PAGES

211-214

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/263211a0

DOI

http://dx.doi.org/10.1038/263211a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036766341

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/822353


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