Model for action of local anaesthetics View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1976-08

AUTHORS

A. G. Lee

ABSTRACT

Sodium channels in nerve membranes are postulated to be surrounded by lipid molecules in the gel (or crystalline) phase. Addition of local anaesthetics triggers a change in the surrounding lipids to the fluid, liquid crystalline phase, allowing the sodium channel to close with resulting local anaesthesia. The experimental evidence for this model is discussed. More... »

PAGES

545-548

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/262545a0

DOI

http://dx.doi.org/10.1038/262545a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033292395

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/958412


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