Complexity of germline and somatic DNA in Ascaris View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1976-01

AUTHORS

KARL B. MORITZ, GÜNTHER E. ROTH

ABSTRACT

DURING the early determination of the blastomeres in the nematode Ascaris chromosomal segments are eliminated in the presomatic cells (chromatin diminution). In the germline, however, all the chromatin is preserved. Similar genome differentiation phenomena have been published1–3. Since no molecular description of chromatin diminution has been made we have begun to study the chromosomes in germline and somatic cells4. It was found that the amount of DNA occurring only in the germ-line chromosomes is not constant5 and that this DNA is not enriched in rDNA6. There is no evidence that the germline-limited DNA is transcribed in vivo7. The results presented here show that the germline DNA of Ascaris contains highly repetitive components, eliminated by the diminution process. Their possible molecular function in connection with germline–soma differentiation and chromosomal behaviour is discussed. More... »

PAGES

55-57

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/259055a0

DOI

http://dx.doi.org/10.1038/259055a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023731994

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1250341


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