Induction of erythroid leukaemia by Harvey and Kirsten sarcoma viruses View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1975-07

AUTHORS

CHARLES D. SCHER, EDWARD M. SCOLNICK, RICHARD SIEGLER

ABSTRACT

SEVERAL RNA tumour viruses including the Friend1, Rauscher2 and Kirsten (MLV-Ki)3 strains cause erythroid leukaemia in mice. These agents do not transform cells in vitro, but provide a helper activity for the replication of defective transforming sarcoma viruses. The Kirsten sarcoma virus (KiSV)4 was isolated from a rat inoculated with MLV-Ki, whereas the Harvey sarcoma virus (HaSV)5 was recovered from a rat infected with the non-transforming Moloney leukaemia helper virus (MLV-M)6. Both sarcoma viruses contain common rat genetic sequences7,8. More... »

PAGES

225-226

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/256225a0

DOI

http://dx.doi.org/10.1038/256225a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041835333

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/168500


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