Conservation of primary structure in 16S ribosomal RNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1975-03

AUTHORS

CARL R. WOESE, GEORGE E. Fox, LAWRENCE ZABLEN, TSUNEKO UCHIDA, LINDA BONEN, KENNETH PECHMAN, BOBBY J. LEWIS, DAVID STAHL

ABSTRACT

THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function1. Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein components2,3. Whether or not this prejudice can be maintained remains to be seen. In any case, the existence of an approximate sequence for a 16S rRNA provides a basis for detailed characterisations of this molecule3,4. Here we begin to define 16S rRNA function by localising the major conserved regions in the molecule through a comparative analysis of 27 prokaryotic 16S rRNA primary structures. More... »

PAGES

83-86

Journal

TITLE

Nature

ISSUE

5495

VOLUME

254

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/254083a0

    DOI

    http://dx.doi.org/10.1038/254083a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1040352006

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/1089909


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