Subunit structure of chromatin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1974-09

AUTHORS

MARKUS NOLL

ABSTRACT

IN the past, the structure of chromatin has remained obscure despite the efforts of many laboratories and seemed far from a simple solution1. It has been known only that chromatin contains a repeating substructure2,3. Recently, however, Kornberg proposed4 that chromatin structure is based on a repeating subunit of 200 base pairs of DNA and two of each of the histones (with the exception of F1 which occurs only once per subunit). Furthermore, he suggested that in chromatin these subunits form a flexibly jointed chain. More... »

PAGES

249-251

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/251249a0

DOI

http://dx.doi.org/10.1038/251249a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044278557

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4422492


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Nucleus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Centrifugation, Density Gradient", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromatin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Electrophoresis, Polyacrylamide Gel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrolysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Micrococcal Nuclease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Weight", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, UK", 
          "id": "http://www.grid.ac/institutes/grid.42475.30", 
          "name": [
            "MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "NOLL", 
        "givenName": "MARKUS", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/newbio241034a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028757472", 
          "https://doi.org/10.1038/newbio241034a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/215508a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005912279", 
          "https://doi.org/10.1038/215508a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/215360a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006407955", 
          "https://doi.org/10.1038/215360a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1974-09", 
    "datePublishedReg": "1974-09-01", 
    "description": "IN the past, the structure of chromatin has remained obscure despite the efforts of many laboratories and seemed far from a simple solution1. It has been known only that chromatin contains a repeating substructure2,3. Recently, however, Kornberg proposed4 that chromatin structure is based on a repeating subunit of 200 base pairs of DNA and two of each of the histones (with the exception of F1 which occurs only once per subunit). Furthermore, he suggested that in chromatin these subunits form a flexibly jointed chain.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/251249a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5472", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "251"
      }
    ], 
    "keywords": [
      "structure of chromatin", 
      "chromatin structure", 
      "chromatin", 
      "repeating subunit", 
      "subunit structure", 
      "base pairs", 
      "subunits", 
      "histones", 
      "DNA", 
      "structure", 
      "pairs", 
      "chain", 
      "laboratory", 
      "efforts", 
      "past", 
      "solution1", 
      "jointed chain", 
      "proposed4"
    ], 
    "name": "Subunit structure of chromatin", 
    "pagination": "249-251", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1044278557"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/251249a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "4422492"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/251249a0", 
      "https://app.dimensions.ai/details/publication/pub.1044278557"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T20:45", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_130.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/251249a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/251249a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/251249a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/251249a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/251249a0'


 

This table displays all metadata directly associated to this object as RDF triples.

134 TRIPLES      21 PREDICATES      58 URIs      47 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/251249a0 schema:about N41eb12ee8ce24e9491c7ea9cb4d577ac
2 N73a327be852f425598d840124ded54de
3 N743416e5583f48caad83947fd6a254b4
4 N9fc73f7c94c14cc480acd79c4ab2bd70
5 Na35fa04ee2f141298eb61d6ecda75936
6 Na5f972165d27425ba2d30504108031a2
7 Nb7e10e9fec2042b68265b32dfecce906
8 Ne536a298dc9f4edc9cb2737cc4071fc7
9 Ne873db76ac3c4d82b2d64fe780a7216e
10 Nef190b6969604198aa48ea0d3b8765f7
11 Nf5ead013c080428ca3cdc067ffe18040
12 anzsrc-for:06
13 anzsrc-for:0601
14 schema:author Nb640b20cc1294879b2e735d37cb86f13
15 schema:citation sg:pub.10.1038/215360a0
16 sg:pub.10.1038/215508a0
17 sg:pub.10.1038/newbio241034a0
18 schema:datePublished 1974-09
19 schema:datePublishedReg 1974-09-01
20 schema:description IN the past, the structure of chromatin has remained obscure despite the efforts of many laboratories and seemed far from a simple solution1. It has been known only that chromatin contains a repeating substructure2,3. Recently, however, Kornberg proposed4 that chromatin structure is based on a repeating subunit of 200 base pairs of DNA and two of each of the histones (with the exception of F1 which occurs only once per subunit). Furthermore, he suggested that in chromatin these subunits form a flexibly jointed chain.
21 schema:genre article
22 schema:isAccessibleForFree false
23 schema:isPartOf Nddc0a37dd95f42a398a486751c0ff73b
24 Nedc101e70f4f49c185d74a523f42909f
25 sg:journal.1018957
26 schema:keywords DNA
27 base pairs
28 chain
29 chromatin
30 chromatin structure
31 efforts
32 histones
33 jointed chain
34 laboratory
35 pairs
36 past
37 proposed4
38 repeating subunit
39 solution1
40 structure
41 structure of chromatin
42 subunit structure
43 subunits
44 schema:name Subunit structure of chromatin
45 schema:pagination 249-251
46 schema:productId N3f8efa302cbc4ca991d5b0c4c2e250d5
47 N49a82530befe4ee5b37acf5fcf13ea93
48 Nbe0724569ad24d4398213c006ecb1e8d
49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044278557
50 https://doi.org/10.1038/251249a0
51 schema:sdDatePublished 2022-11-24T20:45
52 schema:sdLicense https://scigraph.springernature.com/explorer/license/
53 schema:sdPublisher N85fe4f0928724fcfafe8e913e7236083
54 schema:url https://doi.org/10.1038/251249a0
55 sgo:license sg:explorer/license/
56 sgo:sdDataset articles
57 rdf:type schema:ScholarlyArticle
58 N2e0cb62348384f40898e084b573caa60 schema:affiliation grid-institutes:grid.42475.30
59 schema:familyName NOLL
60 schema:givenName MARKUS
61 rdf:type schema:Person
62 N3f8efa302cbc4ca991d5b0c4c2e250d5 schema:name pubmed_id
63 schema:value 4422492
64 rdf:type schema:PropertyValue
65 N41eb12ee8ce24e9491c7ea9cb4d577ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
66 schema:name Electrophoresis, Polyacrylamide Gel
67 rdf:type schema:DefinedTerm
68 N49a82530befe4ee5b37acf5fcf13ea93 schema:name dimensions_id
69 schema:value pub.1044278557
70 rdf:type schema:PropertyValue
71 N73a327be852f425598d840124ded54de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Molecular Weight
73 rdf:type schema:DefinedTerm
74 N743416e5583f48caad83947fd6a254b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name DNA
76 rdf:type schema:DefinedTerm
77 N85fe4f0928724fcfafe8e913e7236083 schema:name Springer Nature - SN SciGraph project
78 rdf:type schema:Organization
79 N9fc73f7c94c14cc480acd79c4ab2bd70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Cell Nucleus
81 rdf:type schema:DefinedTerm
82 Na35fa04ee2f141298eb61d6ecda75936 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Centrifugation, Density Gradient
84 rdf:type schema:DefinedTerm
85 Na5f972165d27425ba2d30504108031a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Micrococcal Nuclease
87 rdf:type schema:DefinedTerm
88 Nb640b20cc1294879b2e735d37cb86f13 rdf:first N2e0cb62348384f40898e084b573caa60
89 rdf:rest rdf:nil
90 Nb7e10e9fec2042b68265b32dfecce906 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Animals
92 rdf:type schema:DefinedTerm
93 Nbe0724569ad24d4398213c006ecb1e8d schema:name doi
94 schema:value 10.1038/251249a0
95 rdf:type schema:PropertyValue
96 Nddc0a37dd95f42a398a486751c0ff73b schema:issueNumber 5472
97 rdf:type schema:PublicationIssue
98 Ne536a298dc9f4edc9cb2737cc4071fc7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Chromatin
100 rdf:type schema:DefinedTerm
101 Ne873db76ac3c4d82b2d64fe780a7216e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Hydrolysis
103 rdf:type schema:DefinedTerm
104 Nedc101e70f4f49c185d74a523f42909f schema:volumeNumber 251
105 rdf:type schema:PublicationVolume
106 Nef190b6969604198aa48ea0d3b8765f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Rats
108 rdf:type schema:DefinedTerm
109 Nf5ead013c080428ca3cdc067ffe18040 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Liver
111 rdf:type schema:DefinedTerm
112 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
113 schema:name Biological Sciences
114 rdf:type schema:DefinedTerm
115 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
116 schema:name Biochemistry and Cell Biology
117 rdf:type schema:DefinedTerm
118 sg:journal.1018957 schema:issn 0028-0836
119 1476-4687
120 schema:name Nature
121 schema:publisher Springer Nature
122 rdf:type schema:Periodical
123 sg:pub.10.1038/215360a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006407955
124 https://doi.org/10.1038/215360a0
125 rdf:type schema:CreativeWork
126 sg:pub.10.1038/215508a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005912279
127 https://doi.org/10.1038/215508a0
128 rdf:type schema:CreativeWork
129 sg:pub.10.1038/newbio241034a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028757472
130 https://doi.org/10.1038/newbio241034a0
131 rdf:type schema:CreativeWork
132 grid-institutes:grid.42475.30 schema:alternateName MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, UK
133 schema:name MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, UK
134 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...