Very long stretches of free DNA in chromatin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1974-08

AUTHORS

A. J. VARSHAVSKY, Yu. V. ILYIN, G. P. GEORGIEV

ABSTRACT

THE arrangement of histones along the DNA in chromosomes has been studied using digestion of the chromatin with DNase1–4 and titration of the chromatin with polylysine2,5 or certain dyes3,6 as probes. The precision of these probes is limited by the extent to which DNA partially covered with histones will react with the enzymes or titration agents used7,8. Furthermore, it has been noted that histones are redistributed along or between DNA fibres under conditions arising during the normal course of isolation and handling of the chromatin9–12. This phenomenon may have strongly influenced the results obtained previously. More... »

PAGES

602-606

References to SciGraph publications

  • 1971-01. Structure of Chromatin in NATURE
  • 1973-10. Redistribution of histones during unfolding of chromosomal DNA in MOLECULAR BIOLOGY REPORTS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/250602a0

    DOI

    http://dx.doi.org/10.1038/250602a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1016383448

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/4845662


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