Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-10

AUTHORS

Frédéric Coin, Jean-Christophe Marinoni, Carlo Rodolfo, Sébastien Fribourg, Antonia Maria Pedrini, Jean-Marc Egly

ABSTRACT

In most cases, xeroderma pigmentosum group D (XP-D) and trichothiodystrophy (TTD) patients carry mutations in the carboxy-terminal domain of the evolutionarily conserved helicase XPD, which is one of the subunits of the transcription/repair factor TFIIH (Refs 1,2). In this study, we demonstrate that XPD interacts specifically with p44, another subunit of TFIIH, and that this interaction results in the stimulation of 5´→3´ helicase activity. Mutations in the XPD C-terminal domain, as found in most patients, prevent the interaction with p44, thus explaining the decrease in XPD helicase activity and the nucleotide excision repair (NER) defect. More... »

PAGES

184-188

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/2491

DOI

http://dx.doi.org/10.1038/2491

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036247542

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9771713


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Helicases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Repair", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Binding Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hair Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factor TFIIH", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors, TFII", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Xeroderma Pigmentosum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Xeroderma Pigmentosum Group D Protein", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Coin", 
        "givenName": "Fr\u00e9d\u00e9ric", 
        "id": "sg:person.01120115241.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120115241.15"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Marinoni", 
        "givenName": "Jean-Christophe", 
        "id": "sg:person.01167130503.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167130503.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419479.6", 
          "name": [
            "Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodolfo", 
        "givenName": "Carlo", 
        "id": "sg:person.0720233330.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720233330.31"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Fribourg", 
        "givenName": "S\u00e9bastien", 
        "id": "sg:person.0651017313.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651017313.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419479.6", 
          "name": [
            "Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pedrini", 
        "givenName": "Antonia Maria", 
        "id": "sg:person.01152131513.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152131513.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419479.6", 
          "name": [
            "Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Egly", 
        "givenName": "Jean-Marc", 
        "id": "sg:person.01062404303.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062404303.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/363114a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042418218", 
          "https://doi.org/10.1038/363114a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/365852a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039325079", 
          "https://doi.org/10.1038/365852a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/374283a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005050997", 
          "https://doi.org/10.1038/374283a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367091a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040254134", 
          "https://doi.org/10.1038/367091a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/374280a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041910268", 
          "https://doi.org/10.1038/374280a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/369578a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013652323", 
          "https://doi.org/10.1038/369578a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1998-10", 
    "datePublishedReg": "1998-10-01", 
    "description": "In most cases, xeroderma pigmentosum group D (XP-D) and trichothiodystrophy (TTD) patients carry mutations in the carboxy-terminal domain of the evolutionarily conserved helicase XPD, which is one of the subunits of the transcription/repair factor TFIIH (Refs 1,2). In this study, we demonstrate that XPD interacts specifically with p44, another subunit of TFIIH, and that this interaction results in the stimulation of 5\u00b4\u21923\u00b4 helicase activity. Mutations in the XPD C-terminal domain, as found in most patients, prevent the interaction with p44, thus explaining the decrease in XPD helicase activity and the nucleotide excision repair (NER) defect.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/2491", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5149909", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1103138", 
        "issn": [
          "1061-4036", 
          "1546-1718"
        ], 
        "name": "Nature Genetics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "20"
      }
    ], 
    "keywords": [
      "xeroderma pigmentosum group D", 
      "most patients", 
      "group D", 
      "trichothiodystrophy patients", 
      "patients", 
      "nucleotide excision repair defect", 
      "TTD phenotype", 
      "excision repair defect", 
      "repair defects", 
      "mutations", 
      "most cases", 
      "gene results", 
      "p44", 
      "stimulation", 
      "p44 subunit", 
      "XPD", 
      "activity", 
      "subunits", 
      "phenotype", 
      "subunits of TFIIH", 
      "carboxy-terminal domain", 
      "transcription/repair factor TFIIH", 
      "decrease", 
      "cases", 
      "study", 
      "helicase activity", 
      "defects", 
      "XPD helicase activity", 
      "C-terminal domain", 
      "TFIIH", 
      "interaction", 
      "results", 
      "helicase XPD", 
      "domain", 
      "XP"
    ], 
    "name": "Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH", 
    "pagination": "184-188", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036247542"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/2491"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9771713"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/2491", 
      "https://app.dimensions.ai/details/publication/pub.1036247542"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_276.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/2491"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/2491'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/2491'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/2491'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/2491'


 

This table displays all metadata directly associated to this object as RDF triples.

206 TRIPLES      21 PREDICATES      80 URIs      66 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/2491 schema:about N1cf2a1a88105449fa53e7a2d480e8375
2 N1ed94de7c41c4f63917e3eed31690785
3 N2f2a933e40874672960749f785ff4ca5
4 N319a00125345486ab936c5dc63188591
5 N42bc4d54733942e687576b2019cc5000
6 N6c8abf017b3740acb4f916d3a63025f1
7 N791786c205d94fc78c9ff999530fdd43
8 Nb64ffeaf5c7c4517a2a4e9856631160b
9 Nb736b49e27b444b48827120f4c06ebc4
10 Nc01d1ea15171406d9afbd930fc5c6d4f
11 Nc7737d60035a4b66bcfba15d10128bfe
12 Ne6271c73bba04e2ea2c4ec364d1a85b8
13 Nfeeb0218820a4affb82c7282258de508
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N8441be7a84c14d91a77e33fab46b6e8c
17 schema:citation sg:pub.10.1038/363114a0
18 sg:pub.10.1038/365852a0
19 sg:pub.10.1038/367091a0
20 sg:pub.10.1038/369578a0
21 sg:pub.10.1038/374280a0
22 sg:pub.10.1038/374283a0
23 schema:datePublished 1998-10
24 schema:datePublishedReg 1998-10-01
25 schema:description In most cases, xeroderma pigmentosum group D (XP-D) and trichothiodystrophy (TTD) patients carry mutations in the carboxy-terminal domain of the evolutionarily conserved helicase XPD, which is one of the subunits of the transcription/repair factor TFIIH (Refs 1,2). In this study, we demonstrate that XPD interacts specifically with p44, another subunit of TFIIH, and that this interaction results in the stimulation of 5´→3´ helicase activity. Mutations in the XPD C-terminal domain, as found in most patients, prevent the interaction with p44, thus explaining the decrease in XPD helicase activity and the nucleotide excision repair (NER) defect.
26 schema:genre article
27 schema:isAccessibleForFree false
28 schema:isPartOf N7f898d3656f942228f4e9b051ef92493
29 Ne0296eeee9be4c78b7b0ee96ee1adbf9
30 sg:journal.1103138
31 schema:keywords C-terminal domain
32 TFIIH
33 TTD phenotype
34 XP
35 XPD
36 XPD helicase activity
37 activity
38 carboxy-terminal domain
39 cases
40 decrease
41 defects
42 domain
43 excision repair defect
44 gene results
45 group D
46 helicase XPD
47 helicase activity
48 interaction
49 most cases
50 most patients
51 mutations
52 nucleotide excision repair defect
53 p44
54 p44 subunit
55 patients
56 phenotype
57 repair defects
58 results
59 stimulation
60 study
61 subunits
62 subunits of TFIIH
63 transcription/repair factor TFIIH
64 trichothiodystrophy patients
65 xeroderma pigmentosum group D
66 schema:name Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH
67 schema:pagination 184-188
68 schema:productId N2fe9346446604d128ee6c720229b4be3
69 N69cf273d3204446caee9316c564b2cf5
70 N95713579fe264a28bf834f50c4761cc5
71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036247542
72 https://doi.org/10.1038/2491
73 schema:sdDatePublished 2022-12-01T06:21
74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
75 schema:sdPublisher N971bfdf6fd3c4edea4edf9d370c51352
76 schema:url https://doi.org/10.1038/2491
77 sgo:license sg:explorer/license/
78 sgo:sdDataset articles
79 rdf:type schema:ScholarlyArticle
80 N1cf2a1a88105449fa53e7a2d480e8375 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name DNA-Binding Proteins
82 rdf:type schema:DefinedTerm
83 N1ed94de7c41c4f63917e3eed31690785 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name DNA Helicases
85 rdf:type schema:DefinedTerm
86 N2f2a933e40874672960749f785ff4ca5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Transcription Factors
88 rdf:type schema:DefinedTerm
89 N2fe9346446604d128ee6c720229b4be3 schema:name dimensions_id
90 schema:value pub.1036247542
91 rdf:type schema:PropertyValue
92 N319a00125345486ab936c5dc63188591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Protein Conformation
94 rdf:type schema:DefinedTerm
95 N417a67c07ac14c95bac6b8acbd8630f5 rdf:first sg:person.01062404303.45
96 rdf:rest rdf:nil
97 N42bc4d54733942e687576b2019cc5000 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Transcription Factor TFIIH
99 rdf:type schema:DefinedTerm
100 N52c808faa9c54d29bdb41098ef225a5a rdf:first sg:person.0720233330.31
101 rdf:rest N5ded9736ece7417b865cd7fdf492460b
102 N5ded9736ece7417b865cd7fdf492460b rdf:first sg:person.0651017313.94
103 rdf:rest Nf924e456fdeb45e0852e996a5bff1d6f
104 N69cf273d3204446caee9316c564b2cf5 schema:name doi
105 schema:value 10.1038/2491
106 rdf:type schema:PropertyValue
107 N6c8abf017b3740acb4f916d3a63025f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name DNA Repair
109 rdf:type schema:DefinedTerm
110 N791786c205d94fc78c9ff999530fdd43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Xeroderma Pigmentosum
112 rdf:type schema:DefinedTerm
113 N7f898d3656f942228f4e9b051ef92493 schema:issueNumber 2
114 rdf:type schema:PublicationIssue
115 N8441be7a84c14d91a77e33fab46b6e8c rdf:first sg:person.01120115241.15
116 rdf:rest N938c467420de4a87a53bf0dabd737502
117 N938c467420de4a87a53bf0dabd737502 rdf:first sg:person.01167130503.25
118 rdf:rest N52c808faa9c54d29bdb41098ef225a5a
119 N95713579fe264a28bf834f50c4761cc5 schema:name pubmed_id
120 schema:value 9771713
121 rdf:type schema:PropertyValue
122 N971bfdf6fd3c4edea4edf9d370c51352 schema:name Springer Nature - SN SciGraph project
123 rdf:type schema:Organization
124 Nb64ffeaf5c7c4517a2a4e9856631160b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Proteins
126 rdf:type schema:DefinedTerm
127 Nb736b49e27b444b48827120f4c06ebc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Mutation
129 rdf:type schema:DefinedTerm
130 Nc01d1ea15171406d9afbd930fc5c6d4f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Xeroderma Pigmentosum Group D Protein
132 rdf:type schema:DefinedTerm
133 Nc7737d60035a4b66bcfba15d10128bfe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Transcription Factors, TFII
135 rdf:type schema:DefinedTerm
136 Ne0296eeee9be4c78b7b0ee96ee1adbf9 schema:volumeNumber 20
137 rdf:type schema:PublicationVolume
138 Ne6271c73bba04e2ea2c4ec364d1a85b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Humans
140 rdf:type schema:DefinedTerm
141 Nf924e456fdeb45e0852e996a5bff1d6f rdf:first sg:person.01152131513.64
142 rdf:rest N417a67c07ac14c95bac6b8acbd8630f5
143 Nfeeb0218820a4affb82c7282258de508 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Hair Diseases
145 rdf:type schema:DefinedTerm
146 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
147 schema:name Medical and Health Sciences
148 rdf:type schema:DefinedTerm
149 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
150 schema:name Clinical Sciences
151 rdf:type schema:DefinedTerm
152 sg:grant.5149909 http://pending.schema.org/fundedItem sg:pub.10.1038/2491
153 rdf:type schema:MonetaryGrant
154 sg:journal.1103138 schema:issn 1061-4036
155 1546-1718
156 schema:name Nature Genetics
157 schema:publisher Springer Nature
158 rdf:type schema:Periodical
159 sg:person.01062404303.45 schema:affiliation grid-institutes:grid.419479.6
160 schema:familyName Egly
161 schema:givenName Jean-Marc
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062404303.45
163 rdf:type schema:Person
164 sg:person.01120115241.15 schema:familyName Coin
165 schema:givenName Frédéric
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120115241.15
167 rdf:type schema:Person
168 sg:person.01152131513.64 schema:affiliation grid-institutes:grid.419479.6
169 schema:familyName Pedrini
170 schema:givenName Antonia Maria
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152131513.64
172 rdf:type schema:Person
173 sg:person.01167130503.25 schema:familyName Marinoni
174 schema:givenName Jean-Christophe
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167130503.25
176 rdf:type schema:Person
177 sg:person.0651017313.94 schema:familyName Fribourg
178 schema:givenName Sébastien
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651017313.94
180 rdf:type schema:Person
181 sg:person.0720233330.31 schema:affiliation grid-institutes:grid.419479.6
182 schema:familyName Rodolfo
183 schema:givenName Carlo
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720233330.31
185 rdf:type schema:Person
186 sg:pub.10.1038/363114a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042418218
187 https://doi.org/10.1038/363114a0
188 rdf:type schema:CreativeWork
189 sg:pub.10.1038/365852a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039325079
190 https://doi.org/10.1038/365852a0
191 rdf:type schema:CreativeWork
192 sg:pub.10.1038/367091a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040254134
193 https://doi.org/10.1038/367091a0
194 rdf:type schema:CreativeWork
195 sg:pub.10.1038/369578a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013652323
196 https://doi.org/10.1038/369578a0
197 rdf:type schema:CreativeWork
198 sg:pub.10.1038/374280a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041910268
199 https://doi.org/10.1038/374280a0
200 rdf:type schema:CreativeWork
201 sg:pub.10.1038/374283a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005050997
202 https://doi.org/10.1038/374283a0
203 rdf:type schema:CreativeWork
204 grid-institutes:grid.419479.6 schema:alternateName Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy
205 schema:name Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso, 207, 27100, Pavia, Italy
206 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...