Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1974-04

AUTHORS

R. M. ZINKEAGEL, P. C. DOHERTY

ABSTRACT

RECENT experiments1–3 indicate that cooperation between thymus derived lymphocytes (T cells) and antibody-forming cell precursors (B cells) is restricted by the H-2 gene complex. Helper activity in vivo operates only when T cells and B cells share at least one set of H-2 antigenic specificities. Evidence is presented here that the interaction of cytotoxic T cells with other somatic cells budding4–5 lymphocytic choriomeningitis (LCM) virus is similarly restricted. More... »

PAGES

701-702

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/248701a0

DOI

http://dx.doi.org/10.1038/248701a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021418039

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4133807


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