Control of neural crest cell fate by the Wnt signalling pathway View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-11-26

AUTHORS

Richard I. Dorsky, Randall T. Moon, David W. Raible

ABSTRACT

Environmental signals are important in the development of neural crest, during which process multipotent progenitor must choose from several fates1,2,3. However, the nature of these environmental signals is unknown. A previous fate map of zebrafish cranial neural crest showed that lineage-restricted clones of pigment cells arise from medial cells near the neural keel, and that clones of neurons arise from lateral cells farther from the neural keel4. Wnt-1 and Wnt-3a are candidate genes for influencing neural crest fate, as they are expressed next to medial, but not lateral, crest cells. Here we determine the role of Wnt signals in modulating the fate of neural crest by injecting messenger RNAs into single, premigratory neural crest cells of zebrafish. Lineage analysis of injected cells shows that activation of Wnt signalling by injection of mRNA encoding cytoplasmic β-catenin promotes pigment-cell formation at the expense of neurons and glia. Conversely, inhibition of the Wnt pathway, by injection of mRNAs encoding either a truncated form of the transcription factor Tcf-3 or a dominant-negative Wnt, promotes neuronal fates at the expense of pigment cells. We conclude that endogenous Wnt signalling normally promotes pigment-cell formation by medial crest cells and thereby contributes to the diversity of neural crest cell fates. More... »

PAGES

370-373

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/24620

DOI

http://dx.doi.org/10.1038/24620

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031886964

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9845073


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Lineage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytoskeletal Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Green Fluorescent Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Luminescent Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neural Crest", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Trans-Activators", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wnt Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wnt1 Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wnt3 Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wnt3A Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zebrafish", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zebrafish Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "beta Catenin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Howard Hughes Medical Institute and Department of Pharmacology, 98195, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Howard Hughes Medical Institute and Department of Pharmacology, 98195, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dorsky", 
        "givenName": "Richard I.", 
        "id": "sg:person.01341206212.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341206212.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Howard Hughes Medical Institute and Department of Pharmacology, 98195, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Howard Hughes Medical Institute and Department of Pharmacology, 98195, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moon", 
        "givenName": "Randall T.", 
        "id": "sg:person.0744713643.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744713643.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biological Structure, University of Washington School of Medicine, 98195, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Biological Structure, University of Washington School of Medicine, 98195, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raible", 
        "givenName": "David W.", 
        "id": "sg:person.01104355264.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104355264.54"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s004270050179", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003160606", 
          "https://doi.org/10.1007/s004270050179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/40146", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029850970", 
          "https://doi.org/10.1038/40146"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1998-11-26", 
    "datePublishedReg": "1998-11-26", 
    "description": "Environmental signals are important in the development of neural crest, during which process multipotent progenitor must choose from several fates1,2,3. However, the nature of these environmental signals is unknown. A previous fate map of zebrafish cranial neural crest showed that lineage-restricted clones of pigment cells arise from medial cells near the neural keel, and that clones of neurons arise from lateral cells farther from the neural keel4. Wnt-1 and Wnt-3a are candidate genes for influencing neural crest fate, as they are expressed next to medial, but not lateral, crest cells. Here we determine the role of Wnt signals in modulating the fate of neural crest by injecting messenger RNAs into single, premigratory neural crest cells of zebrafish. Lineage analysis of injected cells shows that activation of Wnt signalling by injection of mRNA encoding cytoplasmic \u03b2-catenin promotes pigment-cell formation at the expense of neurons and glia. Conversely, inhibition of the Wnt pathway, by injection of mRNAs encoding either a truncated form of the transcription factor Tcf-3 or a dominant-negative Wnt, promotes neuronal fates at the expense of pigment cells. We conclude that endogenous Wnt signalling normally promotes pigment-cell formation by medial crest cells and thereby contributes to the diversity of neural crest cell fates.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/24620", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6709", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "396"
      }
    ], 
    "keywords": [
      "neural crest cell fate", 
      "pigment cell formation", 
      "crest cells", 
      "neural crest", 
      "injection of mRNA", 
      "cell fate", 
      "environmental signals", 
      "zebrafish cranial neural crest", 
      "pigment cells", 
      "premigratory neural crest cells", 
      "expense of neurons", 
      "neural crest fate", 
      "cranial neural crest", 
      "neural crest cells", 
      "activation of Wnt", 
      "neural keel", 
      "TCF-3", 
      "Wnt signals", 
      "lineage analysis", 
      "multipotent progenitors", 
      "cytoplasmic \u03b2-catenin", 
      "neuronal fate", 
      "fate map", 
      "candidate genes", 
      "clones of neurons", 
      "endogenous Wnt", 
      "Wnt-1", 
      "Wnt pathway", 
      "Wnt-3a", 
      "Wnt", 
      "messenger RNA", 
      "\u03b2-catenin", 
      "lateral cells", 
      "fate", 
      "clones", 
      "cells", 
      "mRNA", 
      "pathway", 
      "injected cells", 
      "medial cells", 
      "zebrafish", 
      "genes", 
      "RNA", 
      "progenitors", 
      "diversity", 
      "crest", 
      "neurons", 
      "activation", 
      "glia", 
      "signals", 
      "inhibition", 
      "formation", 
      "role", 
      "keel", 
      "development", 
      "analysis", 
      "maps", 
      "form", 
      "control", 
      "expense", 
      "nature", 
      "injection"
    ], 
    "name": "Control of neural crest cell fate by the Wnt signalling pathway", 
    "pagination": "370-373", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1031886964"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/24620"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9845073"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/24620", 
      "https://app.dimensions.ai/details/publication/pub.1031886964"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_283.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/24620"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/24620'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/24620'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/24620'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/24620'


 

This table displays all metadata directly associated to this object as RDF triples.

224 TRIPLES      21 PREDICATES      108 URIs      98 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/24620 schema:about N08d67946a74d4e228c1f217396932d3b
2 N18d96df1b4f14309b7014dfd6943557e
3 N1a88c6e64b8d4b03ae7c93af56a7603c
4 N2c242cfd764c446d89e8dbcb2fd087ba
5 N37a55505b7574c4bbf463b53c4339db3
6 N3a88bf4eeee24664b2797fe779253fd1
7 N3ac61c69b98e4df68e6b90df69ba00f7
8 N42275603884549dcafef0c13df62c98b
9 N5ad423a8490c42f1ae42dc91ef36c7d5
10 N67cc047505214bc7ad249b8b2fefead6
11 N6da03901e834473583beb6c2f15091ae
12 N8d87c0f807cb4ffeba73245f4a2573d2
13 Na7dc6c5d137f4a8a913d2d100128469c
14 Nb47e99caab5b4ebd9e6df795dfacc1c3
15 Nc8dbc5b7b50043fdaf199bbea2403e8e
16 Ncd1ea00dd9fe466fb586d0bdd20852bb
17 Nd8e5b064ac964047bd31ac77d2fbbe65
18 Nedb45aad63234bbeb62c63a4488085c6
19 Nf202d5437e0945c5ad2f973fe4e4ba9c
20 anzsrc-for:06
21 anzsrc-for:0601
22 schema:author N328d56de641e4a7392ed991f36d95c92
23 schema:citation sg:pub.10.1007/s004270050179
24 sg:pub.10.1038/40146
25 schema:datePublished 1998-11-26
26 schema:datePublishedReg 1998-11-26
27 schema:description Environmental signals are important in the development of neural crest, during which process multipotent progenitor must choose from several fates1,2,3. However, the nature of these environmental signals is unknown. A previous fate map of zebrafish cranial neural crest showed that lineage-restricted clones of pigment cells arise from medial cells near the neural keel, and that clones of neurons arise from lateral cells farther from the neural keel4. Wnt-1 and Wnt-3a are candidate genes for influencing neural crest fate, as they are expressed next to medial, but not lateral, crest cells. Here we determine the role of Wnt signals in modulating the fate of neural crest by injecting messenger RNAs into single, premigratory neural crest cells of zebrafish. Lineage analysis of injected cells shows that activation of Wnt signalling by injection of mRNA encoding cytoplasmic β-catenin promotes pigment-cell formation at the expense of neurons and glia. Conversely, inhibition of the Wnt pathway, by injection of mRNAs encoding either a truncated form of the transcription factor Tcf-3 or a dominant-negative Wnt, promotes neuronal fates at the expense of pigment cells. We conclude that endogenous Wnt signalling normally promotes pigment-cell formation by medial crest cells and thereby contributes to the diversity of neural crest cell fates.
28 schema:genre article
29 schema:isAccessibleForFree false
30 schema:isPartOf N4c525a86b7a34794b559d04ef9ef76b9
31 N5028c8a365464e61a4492bfeb0593ca6
32 sg:journal.1018957
33 schema:keywords RNA
34 TCF-3
35 Wnt
36 Wnt pathway
37 Wnt signals
38 Wnt-1
39 Wnt-3a
40 activation
41 activation of Wnt
42 analysis
43 candidate genes
44 cell fate
45 cells
46 clones
47 clones of neurons
48 control
49 cranial neural crest
50 crest
51 crest cells
52 cytoplasmic β-catenin
53 development
54 diversity
55 endogenous Wnt
56 environmental signals
57 expense
58 expense of neurons
59 fate
60 fate map
61 form
62 formation
63 genes
64 glia
65 inhibition
66 injected cells
67 injection
68 injection of mRNA
69 keel
70 lateral cells
71 lineage analysis
72 mRNA
73 maps
74 medial cells
75 messenger RNA
76 multipotent progenitors
77 nature
78 neural crest
79 neural crest cell fate
80 neural crest cells
81 neural crest fate
82 neural keel
83 neuronal fate
84 neurons
85 pathway
86 pigment cell formation
87 pigment cells
88 premigratory neural crest cells
89 progenitors
90 role
91 signals
92 zebrafish
93 zebrafish cranial neural crest
94 β-catenin
95 schema:name Control of neural crest cell fate by the Wnt signalling pathway
96 schema:pagination 370-373
97 schema:productId N07c9fab10217415483602999c37166b1
98 N3cdbf8ee1120447483d5d0d47ca22963
99 N650f5b3d3f3349ed8c668cdddf071288
100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031886964
101 https://doi.org/10.1038/24620
102 schema:sdDatePublished 2022-10-01T06:30
103 schema:sdLicense https://scigraph.springernature.com/explorer/license/
104 schema:sdPublisher Ndd6886b2df8c4696aa971063922dd660
105 schema:url https://doi.org/10.1038/24620
106 sgo:license sg:explorer/license/
107 sgo:sdDataset articles
108 rdf:type schema:ScholarlyArticle
109 N07c9fab10217415483602999c37166b1 schema:name doi
110 schema:value 10.1038/24620
111 rdf:type schema:PropertyValue
112 N08d67946a74d4e228c1f217396932d3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Mice
114 rdf:type schema:DefinedTerm
115 N18d96df1b4f14309b7014dfd6943557e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Wnt3A Protein
117 rdf:type schema:DefinedTerm
118 N1a88c6e64b8d4b03ae7c93af56a7603c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Animals
120 rdf:type schema:DefinedTerm
121 N2c242cfd764c446d89e8dbcb2fd087ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Green Fluorescent Proteins
123 rdf:type schema:DefinedTerm
124 N328d56de641e4a7392ed991f36d95c92 rdf:first sg:person.01341206212.68
125 rdf:rest N98990d3239ab40d79c7a39de14d3e187
126 N37a55505b7574c4bbf463b53c4339db3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Luminescent Proteins
128 rdf:type schema:DefinedTerm
129 N39dc87b7d4024da19d9b171bb32c7f0f rdf:first sg:person.01104355264.54
130 rdf:rest rdf:nil
131 N3a88bf4eeee24664b2797fe779253fd1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name beta Catenin
133 rdf:type schema:DefinedTerm
134 N3ac61c69b98e4df68e6b90df69ba00f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Proto-Oncogene Proteins
136 rdf:type schema:DefinedTerm
137 N3cdbf8ee1120447483d5d0d47ca22963 schema:name pubmed_id
138 schema:value 9845073
139 rdf:type schema:PropertyValue
140 N42275603884549dcafef0c13df62c98b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Wnt Proteins
142 rdf:type schema:DefinedTerm
143 N4c525a86b7a34794b559d04ef9ef76b9 schema:issueNumber 6709
144 rdf:type schema:PublicationIssue
145 N5028c8a365464e61a4492bfeb0593ca6 schema:volumeNumber 396
146 rdf:type schema:PublicationVolume
147 N5ad423a8490c42f1ae42dc91ef36c7d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Cytoskeletal Proteins
149 rdf:type schema:DefinedTerm
150 N650f5b3d3f3349ed8c668cdddf071288 schema:name dimensions_id
151 schema:value pub.1031886964
152 rdf:type schema:PropertyValue
153 N67cc047505214bc7ad249b8b2fefead6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name RNA, Messenger
155 rdf:type schema:DefinedTerm
156 N6da03901e834473583beb6c2f15091ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Neural Crest
158 rdf:type schema:DefinedTerm
159 N8d87c0f807cb4ffeba73245f4a2573d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Cell Lineage
161 rdf:type schema:DefinedTerm
162 N98990d3239ab40d79c7a39de14d3e187 rdf:first sg:person.0744713643.44
163 rdf:rest N39dc87b7d4024da19d9b171bb32c7f0f
164 Na7dc6c5d137f4a8a913d2d100128469c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Zebrafish Proteins
166 rdf:type schema:DefinedTerm
167 Nb47e99caab5b4ebd9e6df795dfacc1c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Proteins
169 rdf:type schema:DefinedTerm
170 Nc8dbc5b7b50043fdaf199bbea2403e8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Trans-Activators
172 rdf:type schema:DefinedTerm
173 Ncd1ea00dd9fe466fb586d0bdd20852bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Wnt3 Protein
175 rdf:type schema:DefinedTerm
176 Nd8e5b064ac964047bd31ac77d2fbbe65 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Zebrafish
178 rdf:type schema:DefinedTerm
179 Ndd6886b2df8c4696aa971063922dd660 schema:name Springer Nature - SN SciGraph project
180 rdf:type schema:Organization
181 Nedb45aad63234bbeb62c63a4488085c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Signal Transduction
183 rdf:type schema:DefinedTerm
184 Nf202d5437e0945c5ad2f973fe4e4ba9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Wnt1 Protein
186 rdf:type schema:DefinedTerm
187 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
188 schema:name Biological Sciences
189 rdf:type schema:DefinedTerm
190 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
191 schema:name Biochemistry and Cell Biology
192 rdf:type schema:DefinedTerm
193 sg:journal.1018957 schema:issn 0028-0836
194 1476-4687
195 schema:name Nature
196 schema:publisher Springer Nature
197 rdf:type schema:Periodical
198 sg:person.01104355264.54 schema:affiliation grid-institutes:grid.34477.33
199 schema:familyName Raible
200 schema:givenName David W.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104355264.54
202 rdf:type schema:Person
203 sg:person.01341206212.68 schema:affiliation grid-institutes:None
204 schema:familyName Dorsky
205 schema:givenName Richard I.
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341206212.68
207 rdf:type schema:Person
208 sg:person.0744713643.44 schema:affiliation grid-institutes:None
209 schema:familyName Moon
210 schema:givenName Randall T.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744713643.44
212 rdf:type schema:Person
213 sg:pub.10.1007/s004270050179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003160606
214 https://doi.org/10.1007/s004270050179
215 rdf:type schema:CreativeWork
216 sg:pub.10.1038/40146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029850970
217 https://doi.org/10.1038/40146
218 rdf:type schema:CreativeWork
219 grid-institutes:None schema:alternateName Howard Hughes Medical Institute and Department of Pharmacology, 98195, Seattle, Washington, USA
220 schema:name Howard Hughes Medical Institute and Department of Pharmacology, 98195, Seattle, Washington, USA
221 rdf:type schema:Organization
222 grid-institutes:grid.34477.33 schema:alternateName Department of Biological Structure, University of Washington School of Medicine, 98195, Seattle, Washington, USA
223 schema:name Department of Biological Structure, University of Washington School of Medicine, 98195, Seattle, Washington, USA
224 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...