Slightly Deleterious Mutant Substitutions in Evolution View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1973-11

AUTHORS

TOMOKO OHTA

ABSTRACT

RECENT advances in molecular genetics have had a great deal of influence on evolutionary theory, and in particular, the neutral mutation-random drift hypothesis of molecular evolution1,2 has stimulated much interest. The concept of neutral mutant substitution in the population by random genetic drift can be extended to include random fixation of very slightly deleterious mutations which have more chance of being selected against than of being selected for3,4. If this class of mutant substitution is important, we can predict that the evolution is rapid in small populations or at the time of speciation5. Here I shall organize the observed facts which indicate that this class is in fact important. More... »

PAGES

96-98

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/246096a0

DOI

http://dx.doi.org/10.1038/246096a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039946912

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4585855


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