Ontology type: schema:ScholarlyArticle
1972-01
AUTHORSS. R. HOLLÁN, J. G. SZELENYI, B. BRIMHALL, M. DUERST, R. T. JONES, R. D. KOLER, Z. STOCKLEN
ABSTRACTIT is well established that at least two independent loci control the structure of human haemoglobin A1,2. Although the primary structure of the β-chain is determined by a single genetic locus, there are conflicting reports that the α-chain is controlled by one3 or two4,5 loci. We now describe genetic and chemical studies of a Budapest family which possess two abnormal α-chain haemoglobins, Hb J-Buda and Hb G-Pest, and review evidence for multiple loci for the α-chain. More... »
PAGES47-50
http://scigraph.springernature.com/pub.10.1038/235047a0
DOIhttp://dx.doi.org/10.1038/235047a0
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