Immunological Inhibition of Lysosome Function View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1970-12

AUTHORS

PAUL TULKENS, ANDRÉ TROUET, FRANÇOIS VAN HOOF

ABSTRACT

Antibodies directed against soluble components from purified liver lysosomes are taken up by fibroblasts and to impair lysosomal function. As a result, lysosomal hydrolases are inhibited, the uptake and digestion of foreign protein are impaired and there is a marked increase in the size and number of lysosome-like cytoplasmic bodies—resembling the condition seen in many storage diseases. More... »

PAGES

1282

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/2281282a0

DOI

http://dx.doi.org/10.1038/2281282a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011867572

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4098956


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