Prolongation of Skin Allograft Survival with Spleen Extracts and Antilymphocytic Serum View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1970-08

AUTHORS

L. BRENT, P. J. KILSHAW

ABSTRACT

A single dose of splenic extract is sufficient to induce a high degree of specific unresponsiveness to skin allografts in mice if used in conjunction with antilymphocytic serum. The interval between giving the extract and the antiserum is of great importance, and the unresponsiveness appears to be due to tolerance rather than enhancement. More... »

PAGES

898-900

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/227898a0

DOI

http://dx.doi.org/10.1038/227898a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039174605

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4915404


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antilymphocyte Serum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Synergism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histocompatibility", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immune Tolerance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Extracts", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymph Nodes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rabbits", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Skin Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spleen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tissue Extracts", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Homologous", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Immunology, St Mary's Hospital Medical School, W2, London", 
          "id": "http://www.grid.ac/institutes/grid.426467.5", 
          "name": [
            "Department of Immunology, St Mary's Hospital Medical School, W2, London"
          ], 
          "type": "Organization"
        }, 
        "familyName": "BRENT", 
        "givenName": "L.", 
        "id": "sg:person.01102552101.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102552101.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Immunology, St Mary's Hospital Medical School, W2, London", 
          "id": "http://www.grid.ac/institutes/grid.426467.5", 
          "name": [
            "Department of Immunology, St Mary's Hospital Medical School, W2, London"
          ], 
          "type": "Organization"
        }, 
        "familyName": "KILSHAW", 
        "givenName": "P. J.", 
        "id": "sg:person.046276352.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.046276352.20"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1970-08", 
    "datePublishedReg": "1970-08-01", 
    "description": "A single dose of splenic extract is sufficient to induce a high degree of specific unresponsiveness to skin allografts in mice if used in conjunction with antilymphocytic serum. The interval between giving the extract and the antiserum is of great importance, and the unresponsiveness appears to be due to tolerance rather than enhancement.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/227898a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5261", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "227"
      }
    ], 
    "keywords": [
      "antilymphocytic serum", 
      "skin allograft survival", 
      "allograft survival", 
      "specific unresponsiveness", 
      "single dose", 
      "splenic extract", 
      "spleen extracts", 
      "unresponsiveness", 
      "serum", 
      "allografts", 
      "extract", 
      "mice", 
      "dose", 
      "prolongation", 
      "survival", 
      "antiserum", 
      "interval", 
      "high degree", 
      "tolerance", 
      "degree", 
      "conjunction", 
      "importance", 
      "great importance", 
      "enhancement"
    ], 
    "name": "Prolongation of Skin Allograft Survival with Spleen Extracts and Antilymphocytic Serum", 
    "pagination": "898-900", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039174605"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/227898a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "4915404"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/227898a0", 
      "https://app.dimensions.ai/details/publication/pub.1039174605"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:17", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_122.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/227898a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/227898a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/227898a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/227898a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/227898a0'


 

This table displays all metadata directly associated to this object as RDF triples.

152 TRIPLES      20 PREDICATES      65 URIs      57 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/227898a0 schema:about N0583695d231a4ea5b6bfeba29977052b
2 N1003c2175607444b9b944fe3acd11e07
3 N12f409e135cc41a0b0fa14c8aab80326
4 N1f4ec5f442134fc3aba29e2b39dbb6b6
5 N3cd5698337e249308d3c3ef3518920d6
6 N4622bcef2ed44f74b6e90c0e31474423
7 N4cb766c872664c5f90c6252c9c7d2450
8 N55cde72dba3b4442b1a3c0dd61cdc04b
9 N57d636042a444919a401a6b936ac9bab
10 N611b65ab3c0442c98cb938ea4c018aad
11 N72ceb63c2c8242399f3dfa7130aa0de2
12 N90cf059ca5184ffea2005576e3c0e5fc
13 N938d89a6a0144f1f876cf9979f4a588f
14 Nb2c74da9936348c8ba484de234eff540
15 Nf8917bf4d2554d029c396ada0766ee68
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author Nd1caa235defc4fe899f068265d26975b
19 schema:datePublished 1970-08
20 schema:datePublishedReg 1970-08-01
21 schema:description A single dose of splenic extract is sufficient to induce a high degree of specific unresponsiveness to skin allografts in mice if used in conjunction with antilymphocytic serum. The interval between giving the extract and the antiserum is of great importance, and the unresponsiveness appears to be due to tolerance rather than enhancement.
22 schema:genre article
23 schema:isAccessibleForFree false
24 schema:isPartOf N5ef09dc738e041d0adcb033236b050be
25 N86bbbc45e293416d9183e814a73267a4
26 sg:journal.1018957
27 schema:keywords allograft survival
28 allografts
29 antilymphocytic serum
30 antiserum
31 conjunction
32 degree
33 dose
34 enhancement
35 extract
36 great importance
37 high degree
38 importance
39 interval
40 mice
41 prolongation
42 serum
43 single dose
44 skin allograft survival
45 specific unresponsiveness
46 spleen extracts
47 splenic extract
48 survival
49 tolerance
50 unresponsiveness
51 schema:name Prolongation of Skin Allograft Survival with Spleen Extracts and Antilymphocytic Serum
52 schema:pagination 898-900
53 schema:productId N2f73aeec24f54781bf245593da195aac
54 N366f6b9665574fa589c36da8fd23afa3
55 Nf9b9b729a9b643928713810e34f41fc5
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039174605
57 https://doi.org/10.1038/227898a0
58 schema:sdDatePublished 2022-12-01T06:17
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher N542264436e7340f99848ac4b8c54fb6b
61 schema:url https://doi.org/10.1038/227898a0
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N0583695d231a4ea5b6bfeba29977052b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
66 schema:name Tissue Extracts
67 rdf:type schema:DefinedTerm
68 N1003c2175607444b9b944fe3acd11e07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Spleen
70 rdf:type schema:DefinedTerm
71 N12f409e135cc41a0b0fa14c8aab80326 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Transplantation, Homologous
73 rdf:type schema:DefinedTerm
74 N1f4ec5f442134fc3aba29e2b39dbb6b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Mice
76 rdf:type schema:DefinedTerm
77 N2f73aeec24f54781bf245593da195aac schema:name pubmed_id
78 schema:value 4915404
79 rdf:type schema:PropertyValue
80 N366f6b9665574fa589c36da8fd23afa3 schema:name doi
81 schema:value 10.1038/227898a0
82 rdf:type schema:PropertyValue
83 N3cd5698337e249308d3c3ef3518920d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Liver Extracts
85 rdf:type schema:DefinedTerm
86 N4622bcef2ed44f74b6e90c0e31474423 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Skin Transplantation
88 rdf:type schema:DefinedTerm
89 N4cb766c872664c5f90c6252c9c7d2450 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Transplantation Immunology
91 rdf:type schema:DefinedTerm
92 N542264436e7340f99848ac4b8c54fb6b schema:name Springer Nature - SN SciGraph project
93 rdf:type schema:Organization
94 N55cde72dba3b4442b1a3c0dd61cdc04b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Rabbits
96 rdf:type schema:DefinedTerm
97 N57d636042a444919a401a6b936ac9bab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Immune Tolerance
99 rdf:type schema:DefinedTerm
100 N5ef09dc738e041d0adcb033236b050be schema:issueNumber 5261
101 rdf:type schema:PublicationIssue
102 N611b65ab3c0442c98cb938ea4c018aad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Kidney Transplantation
104 rdf:type schema:DefinedTerm
105 N72ceb63c2c8242399f3dfa7130aa0de2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Animals
107 rdf:type schema:DefinedTerm
108 N86bbbc45e293416d9183e814a73267a4 schema:volumeNumber 227
109 rdf:type schema:PublicationVolume
110 N90cf059ca5184ffea2005576e3c0e5fc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Antilymphocyte Serum
112 rdf:type schema:DefinedTerm
113 N938d89a6a0144f1f876cf9979f4a588f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Lymph Nodes
115 rdf:type schema:DefinedTerm
116 Nb2c74da9936348c8ba484de234eff540 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Histocompatibility
118 rdf:type schema:DefinedTerm
119 Nd1caa235defc4fe899f068265d26975b rdf:first sg:person.01102552101.81
120 rdf:rest Nf0b2e9297cd64f208c02d41e307cfaf5
121 Nf0b2e9297cd64f208c02d41e307cfaf5 rdf:first sg:person.046276352.20
122 rdf:rest rdf:nil
123 Nf8917bf4d2554d029c396ada0766ee68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Drug Synergism
125 rdf:type schema:DefinedTerm
126 Nf9b9b729a9b643928713810e34f41fc5 schema:name dimensions_id
127 schema:value pub.1039174605
128 rdf:type schema:PropertyValue
129 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
130 schema:name Medical and Health Sciences
131 rdf:type schema:DefinedTerm
132 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
133 schema:name Clinical Sciences
134 rdf:type schema:DefinedTerm
135 sg:journal.1018957 schema:issn 0028-0836
136 1476-4687
137 schema:name Nature
138 schema:publisher Springer Nature
139 rdf:type schema:Periodical
140 sg:person.01102552101.81 schema:affiliation grid-institutes:grid.426467.5
141 schema:familyName BRENT
142 schema:givenName L.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102552101.81
144 rdf:type schema:Person
145 sg:person.046276352.20 schema:affiliation grid-institutes:grid.426467.5
146 schema:familyName KILSHAW
147 schema:givenName P. J.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.046276352.20
149 rdf:type schema:Person
150 grid-institutes:grid.426467.5 schema:alternateName Department of Immunology, St Mary's Hospital Medical School, W2, London
151 schema:name Department of Immunology, St Mary's Hospital Medical School, W2, London
152 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...