Shared Viral Antigen of Mammalian Leukaemia Viruses View Full Text


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Article Info

DATE

1970-04

AUTHORS

GAYLA GEERING, TADAO AOKI, LLOYD J. OLD

ABSTRACT

IN 1966, Geering, Old and Boyse1 identified group-specific (gs) antigens of murine leukaemia viruses (MuLV) in immunoprecipitation tests with antigen in the form of disrupted virions or extracts of infected tissue. Antisera containing a wide range of precipitating MuLV antibodies are obtained from inbred rats bearing large subcutaneous transplants of syngeneic leukaemias induced by wild-type Gross virus1. Usually a large number of rats have to be screened in order to find one with antibody to the complete set of MuLV antigens known to be demonstrable by immunoprecipitation. Rats which have both a massive local tumour and metastasis to local lymph nodes, and which have survived for a comparatively long time after they received the leukaemic transplants, are most likely to yield such antisera. More... »

PAGES

265-266

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/226265a0

DOI

http://dx.doi.org/10.1038/226265a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010389239

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4314416


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