Homing of Lymph-borne Immunoblasts to the Gut View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1970-04

AUTHORS

J. G. HALL, MARILYN E. SMITH

ABSTRACT

BETWEEN 3 and 6 days after antigenic stimulation, lymph nodes discharge large numbers of basophilic blast cells (immunoblasts) into the efferent lymph which carries them to the blood1–3. These cells contain many polyribosomes but little endoplasmic reticulum; nevertheless, they produce specific antibody1,4,5 and are specifically cytotoxic in vitro6. Unlike small lymphocytes they incorporate DNA precursors with avidity and some of them transform into true plasma cells in vivo7. Immunoblasts produced by the caudal lymph nodes of rats can be obtained by collecting the thoracic duct lymph 3–6 days after antigenic stimulation of the hindquarter regions8,9. More... »

PAGES

262-263

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/226262a0

DOI

http://dx.doi.org/10.1038/226262a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046707137

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5461810


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