Amber Suppression: a Nucleotide Change in the Anticodon of a Tyrosine Transfer RNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1968-03

AUTHORS

HOWARD M. GOODMAN, JOHN ABELSON, ARTHUR LANDY, S. BRENNER, J. D. SMITH

ABSTRACT

In certain mutants a single base change alters the meaning of a messenger codon in such a way that, instead of spelling out an amino-acid, it spells out chain termination. Mutants in a quite different gene, called a suppression gene, allow the chain-terminating triplet to be read as an amino-acid. Experiments have shown that this is caused by a mutated tRNA which carries a single base change in its anticodon. This allows it to read the chain-terminating codon as if it spelt tyrosine. More... »

PAGES

1019-1024

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/2171019a0

DOI

http://dx.doi.org/10.1038/2171019a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052082985

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5643523


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