Non-randomness of Ammo-acid Changes in the Evolution of Homologous Proteins View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1967-07

AUTHORS

CHARLES J. EPSTEIN

ABSTRACT

A calculation of the extent of the differences between homologous proteins shows that the amino-acid “mutations” are not as random as might have been thought. In fact, natural selection seems to act to favour those amino-acid substitutions that tend to maintain the original conformation of the protein.

PAGES

355-359

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/215355a0

DOI

http://dx.doi.org/10.1038/215355a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010193747

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4964553


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