Unitary Excitatory Postsynaptic Potentials in Clarke's Column Neurones View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1967-09

AUTHORS

E. EIDE, L. FEDINA, J. JANSEN, A. LUNDBERG, L. VYKLICKÝ

ABSTRACT

IT is generally believed that synaptic transmission is effected by a quantal release of transmitter substances, such as has been demonstrated for the neuromuscular junction1. The quantal nature of synaptic transmission in the central nervous system is more difficult to investigate, one reason being that many presynaptic fibres usually contribute to the EPSP (excitatory postsynaptic potential), whereas at the neuromuscular junction the entire effect is evoked from a single presynaptic fibre. Thus at central synapses the total synaptic action should be described both in terms of the number of unitary EPSPs (the EPSP contributed by a single presynaptic fibre) and the quantal composition of each unitary EPSP. In motoneurones, impulses in Ia afferents (large muscle spindle afferents) usually evoke small unitary EPSPs with a low quantal content2, but larger unitary Ia EPSPs with quantal content “possibly as high as ten or fifteen” have also been found3. More... »

PAGES

1176-1177

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/2151176a0

DOI

http://dx.doi.org/10.1038/2151176a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012219634

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4294062


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cordotomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membrane Potentials", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuromuscular Junction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spinal Cord", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Synapses", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Synaptic Transmission", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg", 
          "id": "http://www.grid.ac/institutes/grid.8761.8", 
          "name": [
            "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg"
          ], 
          "type": "Organization"
        }, 
        "familyName": "EIDE", 
        "givenName": "E.", 
        "id": "sg:person.050152146.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.050152146.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg", 
          "id": "http://www.grid.ac/institutes/grid.8761.8", 
          "name": [
            "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg"
          ], 
          "type": "Organization"
        }, 
        "familyName": "FEDINA", 
        "givenName": "L.", 
        "id": "sg:person.0112713574.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0112713574.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurophysiology, Oslo, Norway", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg", 
            "Department of Neurophysiology, Oslo, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "JANSEN", 
        "givenName": "J.", 
        "id": "sg:person.057654346.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.057654346.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg", 
          "id": "http://www.grid.ac/institutes/grid.8761.8", 
          "name": [
            "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg"
          ], 
          "type": "Organization"
        }, 
        "familyName": "LUNDBERG", 
        "givenName": "A.", 
        "id": "sg:person.061622077.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.061622077.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Czechoslovak Academy of Sciences, Prague, Czechoslovakia", 
          "id": "http://www.grid.ac/institutes/grid.418095.1", 
          "name": [
            "Department of Physiology, University of G\u00f6teborg, G\u00f6teborg", 
            "Czechoslovak Academy of Sciences, Prague, Czechoslovakia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "VYKLICK\u00dd", 
        "givenName": "L.", 
        "id": "sg:person.053115663.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053115663.15"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1967-09", 
    "datePublishedReg": "1967-09-01", 
    "description": "IT is generally believed that synaptic transmission is effected by a quantal release of transmitter substances, such as has been demonstrated for the neuromuscular junction1. The quantal nature of synaptic transmission in the central nervous system is more difficult to investigate, one reason being that many presynaptic fibres usually contribute to the EPSP (excitatory postsynaptic potential), whereas at the neuromuscular junction the entire effect is evoked from a single presynaptic fibre. Thus at central synapses the total synaptic action should be described both in terms of the number of unitary EPSPs (the EPSP contributed by a single presynaptic fibre) and the quantal composition of each unitary EPSP. In motoneurones, impulses in Ia afferents (large muscle spindle afferents) usually evoke small unitary EPSPs with a low quantal content2, but larger unitary Ia EPSPs with quantal content \u201cpossibly as high as ten or fifteen\u201d have also been found3.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/2151176a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5106", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "215"
      }
    ], 
    "keywords": [
      "unitary EPSPs", 
      "presynaptic fibers", 
      "synaptic transmission", 
      "unitary excitatory postsynaptic potentials", 
      "excitatory postsynaptic potentials", 
      "central nervous system", 
      "single presynaptic fibers", 
      "Ia afferents", 
      "postsynaptic potentials", 
      "synaptic actions", 
      "transmitter substances", 
      "quantal content", 
      "central synapses", 
      "nervous system", 
      "neuromuscular junction", 
      "EPSPs", 
      "quantal release", 
      "quantal nature", 
      "afferents", 
      "motoneurones", 
      "neurones", 
      "synapses", 
      "entire effect", 
      "transmission", 
      "release", 
      "substances", 
      "fibers", 
      "action", 
      "effect", 
      "junction", 
      "number", 
      "reasons", 
      "impulses", 
      "potential", 
      "content", 
      "system", 
      "terms", 
      "nature", 
      "composition", 
      "IT", 
      "neuromuscular junction1", 
      "total synaptic action", 
      "quantal composition", 
      "small unitary EPSPs", 
      "low quantal content2", 
      "quantal content2", 
      "content2", 
      "Clarke's Column Neurones", 
      "'s Column Neurones"
    ], 
    "name": "Unitary Excitatory Postsynaptic Potentials in Clarke's Column Neurones", 
    "pagination": "1176-1177", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1012219634"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/2151176a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "4294062"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/2151176a0", 
      "https://app.dimensions.ai/details/publication/pub.1012219634"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T17:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_103.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/2151176a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/2151176a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/2151176a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/2151176a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/2151176a0'


 

This table displays all metadata directly associated to this object as RDF triples.

182 TRIPLES      20 PREDICATES      84 URIs      76 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/2151176a0 schema:about N014b4c89839d40bc98cc21b259598e49
2 N0432b74208a441abbba3d0dfc2f4c08b
3 N0a2f30fa523943de8c2652e0c90c6156
4 N1db60a05fffc46a38e1bfc66b27e7cff
5 N4b8654489b3a46b2abc189d70b0d855a
6 N61998eb738864594983ac91484eae968
7 N786ae3631ddf4bd7a3e538500386ee0c
8 Nac90aae91dd14acf85e817ddf837aaff
9 Neeb4f9d64ab54c6eae6dc33f0a30c197
10 anzsrc-for:11
11 anzsrc-for:1109
12 schema:author N0f1b8a49c8e046bc8a20fda9f0928693
13 schema:datePublished 1967-09
14 schema:datePublishedReg 1967-09-01
15 schema:description IT is generally believed that synaptic transmission is effected by a quantal release of transmitter substances, such as has been demonstrated for the neuromuscular junction1. The quantal nature of synaptic transmission in the central nervous system is more difficult to investigate, one reason being that many presynaptic fibres usually contribute to the EPSP (excitatory postsynaptic potential), whereas at the neuromuscular junction the entire effect is evoked from a single presynaptic fibre. Thus at central synapses the total synaptic action should be described both in terms of the number of unitary EPSPs (the EPSP contributed by a single presynaptic fibre) and the quantal composition of each unitary EPSP. In motoneurones, impulses in Ia afferents (large muscle spindle afferents) usually evoke small unitary EPSPs with a low quantal content2, but larger unitary Ia EPSPs with quantal content “possibly as high as ten or fifteen” have also been found3.
16 schema:genre article
17 schema:isAccessibleForFree false
18 schema:isPartOf N6761766bfb19435b85d92a26ebecd10b
19 Nb8fa05a97e864ed5aca2928772330159
20 sg:journal.1018957
21 schema:keywords 's Column Neurones
22 Clarke's Column Neurones
23 EPSPs
24 IT
25 Ia afferents
26 action
27 afferents
28 central nervous system
29 central synapses
30 composition
31 content
32 content2
33 effect
34 entire effect
35 excitatory postsynaptic potentials
36 fibers
37 impulses
38 junction
39 low quantal content2
40 motoneurones
41 nature
42 nervous system
43 neuromuscular junction
44 neuromuscular junction1
45 neurones
46 number
47 postsynaptic potentials
48 potential
49 presynaptic fibers
50 quantal composition
51 quantal content
52 quantal content2
53 quantal nature
54 quantal release
55 reasons
56 release
57 single presynaptic fibers
58 small unitary EPSPs
59 substances
60 synapses
61 synaptic actions
62 synaptic transmission
63 system
64 terms
65 total synaptic action
66 transmission
67 transmitter substances
68 unitary EPSPs
69 unitary excitatory postsynaptic potentials
70 schema:name Unitary Excitatory Postsynaptic Potentials in Clarke's Column Neurones
71 schema:pagination 1176-1177
72 schema:productId N0c31d597044e449f978f74dfb92d1c83
73 N30bac1a7504b4eee9b22ae9cc099b8ec
74 N3f4d1895e675453e846f025fc1b2ae1a
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012219634
76 https://doi.org/10.1038/2151176a0
77 schema:sdDatePublished 2022-01-01T17:59
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher N9e40f1e60788479db32ed7cd73324883
80 schema:url https://doi.org/10.1038/2151176a0
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N014b4c89839d40bc98cc21b259598e49 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Cats
86 rdf:type schema:DefinedTerm
87 N0432b74208a441abbba3d0dfc2f4c08b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Synapses
89 rdf:type schema:DefinedTerm
90 N0a2f30fa523943de8c2652e0c90c6156 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Membrane Potentials
92 rdf:type schema:DefinedTerm
93 N0c31d597044e449f978f74dfb92d1c83 schema:name pubmed_id
94 schema:value 4294062
95 rdf:type schema:PropertyValue
96 N0f1b8a49c8e046bc8a20fda9f0928693 rdf:first sg:person.050152146.94
97 rdf:rest N914f71cf33fe4fbaa3656a3f1bf8a7b6
98 N1db60a05fffc46a38e1bfc66b27e7cff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Cordotomy
100 rdf:type schema:DefinedTerm
101 N30bac1a7504b4eee9b22ae9cc099b8ec schema:name doi
102 schema:value 10.1038/2151176a0
103 rdf:type schema:PropertyValue
104 N3f4d1895e675453e846f025fc1b2ae1a schema:name dimensions_id
105 schema:value pub.1012219634
106 rdf:type schema:PropertyValue
107 N4b8654489b3a46b2abc189d70b0d855a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Neurons
109 rdf:type schema:DefinedTerm
110 N57348852670d4244878e4f37080a9daa rdf:first sg:person.057654346.34
111 rdf:rest N857eab5816f7434f80b00f01f819c6ee
112 N61998eb738864594983ac91484eae968 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Synaptic Transmission
114 rdf:type schema:DefinedTerm
115 N6761766bfb19435b85d92a26ebecd10b schema:volumeNumber 215
116 rdf:type schema:PublicationVolume
117 N786ae3631ddf4bd7a3e538500386ee0c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Animals
119 rdf:type schema:DefinedTerm
120 N857eab5816f7434f80b00f01f819c6ee rdf:first sg:person.061622077.32
121 rdf:rest N86ccb414858e48a4976ece702c755a4a
122 N86ccb414858e48a4976ece702c755a4a rdf:first sg:person.053115663.15
123 rdf:rest rdf:nil
124 N914f71cf33fe4fbaa3656a3f1bf8a7b6 rdf:first sg:person.0112713574.06
125 rdf:rest N57348852670d4244878e4f37080a9daa
126 N9e40f1e60788479db32ed7cd73324883 schema:name Springer Nature - SN SciGraph project
127 rdf:type schema:Organization
128 Nac90aae91dd14acf85e817ddf837aaff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Neuromuscular Junction
130 rdf:type schema:DefinedTerm
131 Nb8fa05a97e864ed5aca2928772330159 schema:issueNumber 5106
132 rdf:type schema:PublicationIssue
133 Neeb4f9d64ab54c6eae6dc33f0a30c197 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Spinal Cord
135 rdf:type schema:DefinedTerm
136 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
137 schema:name Medical and Health Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
140 schema:name Neurosciences
141 rdf:type schema:DefinedTerm
142 sg:journal.1018957 schema:issn 0028-0836
143 1476-4687
144 schema:name Nature
145 schema:publisher Springer Nature
146 rdf:type schema:Periodical
147 sg:person.0112713574.06 schema:affiliation grid-institutes:grid.8761.8
148 schema:familyName FEDINA
149 schema:givenName L.
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0112713574.06
151 rdf:type schema:Person
152 sg:person.050152146.94 schema:affiliation grid-institutes:grid.8761.8
153 schema:familyName EIDE
154 schema:givenName E.
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.050152146.94
156 rdf:type schema:Person
157 sg:person.053115663.15 schema:affiliation grid-institutes:grid.418095.1
158 schema:familyName VYKLICKÝ
159 schema:givenName L.
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053115663.15
161 rdf:type schema:Person
162 sg:person.057654346.34 schema:affiliation grid-institutes:None
163 schema:familyName JANSEN
164 schema:givenName J.
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.057654346.34
166 rdf:type schema:Person
167 sg:person.061622077.32 schema:affiliation grid-institutes:grid.8761.8
168 schema:familyName LUNDBERG
169 schema:givenName A.
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.061622077.32
171 rdf:type schema:Person
172 grid-institutes:None schema:alternateName Department of Neurophysiology, Oslo, Norway
173 schema:name Department of Neurophysiology, Oslo, Norway
174 Department of Physiology, University of Göteborg, Göteborg
175 rdf:type schema:Organization
176 grid-institutes:grid.418095.1 schema:alternateName Czechoslovak Academy of Sciences, Prague, Czechoslovakia
177 schema:name Czechoslovak Academy of Sciences, Prague, Czechoslovakia
178 Department of Physiology, University of Göteborg, Göteborg
179 rdf:type schema:Organization
180 grid-institutes:grid.8761.8 schema:alternateName Department of Physiology, University of Göteborg, Göteborg
181 schema:name Department of Physiology, University of Göteborg, Göteborg
182 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...