Operon Hypothesis: New Evidence from the ‘Constant Proportion’ Group of the Embden–Meyerhof Pathway View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1966-03

AUTHORS

P. D. MIER, D. W. K. COTTON

ABSTRACT

A NUMBER of examples have now been reported in which a group of enzymes is synthesized in such a manner that the relative activity of each of the enzymes within, the group is constant. An important example of this is the ‘constant-proportion’ group in the Embden–Meyerhof pathway, which has been extensively investigated by Vogell et al.1 and by Pette et al.2. These workers examined a wide range of materials, extending from baker's yeast to various mammalian tissues, and found that the activity of the five enzymes, triosephosphate isomerase to enolase, formed a pattern which is quite reproducible. They suggest that this indicates a “co-ordinate control of enzyme synthesis” by the cell at the molecular level, a subject which has been the focal point of much recent attention. More... »

PAGES

1022-1023

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/2091022b0

DOI

http://dx.doi.org/10.1038/2091022b0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021554112

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5927508


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