Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1962-05

AUTHORS

W. M. HUNTER, F. C. GREENWOOD

ABSTRACT

RECENT procedures for the immunological assay of protein hormones in human plasma1–3 require the routine preparation of hormones labelled with iodine-131 of high specific activity.

PAGES

495-496

References to SciGraph publications

Journal

TITLE

Nature

ISSUE

4827

VOLUME

194

Related Patents

  • Method For Efficient Delivery Of Therapeutic Molecules In Vitro And In Vivo
  • Assays For Detecting Antibodies Specific To Therapeutic Anti-Ige Antibodies And Their Use In Anaphylaxis
  • Antibodies Directed Against Lymphocyte Activation Gene 3 (Lag-3)
  • Antibodies To Dcr3 Polypeptide, A Tnfr Homolog
  • Nucleotide Sequences Coding Polypeptide For Use In The Treatment And Prevention Of Infections, Inflammation, Allergenic, Lung, Skin And Cancer Disorders
  • Compositions And Methods For Cancer
  • Cdna Encoding A Gene Bog (B5t Over-Expressed Gene) And Its Protein Product
  • Induces Mammalian Cancer Cell Apoptosis; Used To Treat Cancer
  • Dna Encoding A Soluble Vegf Inhibitor
  • Method Of Treating Pustular Psoriasis With Antibodies Directed Against Interleukin 36 Receptor (Il-36r)
  • Idiotypic Antibodies Against Anti-Pd-L1 Antibodies And Uses Thereof
  • Constructs Targeting Afp Peptide/Mhc Complexes And Uses Thereof
  • Antibodies Directed Against Interleukin-33 (Il-33) And Methods Of Making And Using
  • Anti-Cd151 Antibodies And Their Use In The Treatment Of Cancer
  • Ultrapurified Dsba And Dsbc And Methods Of Making And Using The Same
  • Methods Of Screening For Trpm5 Modulators
  • Apo-2 Ligand
  • Constructs Targeting Histone H3 Peptide/Mhc Complexes And Uses Thereof
  • Nipple Covering System
  • Altered April Binding Antibodies
  • Methods For Producing Humanized Antibodies And Improving Yield Of Antibodies Or Antigen Binding Fragments In Cell Culture
  • Smoothened Polypeptides For Binding Patched
  • Compositions And Methods For Inhibiting Matrix Metalloproteinase (Mmp)-Mediated Cell Migration
  • Antibodies Directed Against T Cell Immunoglobulin And Mucin Protein 3 (Tim-3)
  • Apo-2 Receptor Polypeptides
  • Solubility Forms; Skin Disorders, Rheumatic Disorders, Antidiabetic Agents
  • Antibodies Directed Against Programmed Death-1 (Pd-1)
  • Cross-Screening System And Methods For Detecting A Molecule Having Binding Affinity For A Target Molecule
  • Anti-Htra1 Antibodies And Methods Of Use
  • Cyclic Peptides And Methods Of Use Thereof
  • Apo-2 Ligand
  • Variants Of Vascular Endothelial Cell Growth Factor
  • Nucleic Acids Encoding Anti-Neonatal Fc Receptor (Fcrn) Antibodies
  • Anti Cxcr4 Antibodies And Their Use For The Treatment Of Cancer
  • Antibodies Directed Against Interleukin 36 Receptor (Il-36r)
  • Apo-2-Receptor
  • Hepatocyte Growth Factor Receptor Antagonist Antibodies And Uses Thereof
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Nucleic Acids Coding For Adhesion Factors Of Group B Streptococcus, Adhesion Factors Of Group B Streptococcus And Futher Uses Thereof
  • Anti-Htra1 Antibodies And Methods Of Use Thereof
  • Antibodies To Apo-2 Receptor Polypeptides
  • Detecting Amount Of Labelled Peptide Bound To Silk; Useful In Detecting Or Monitoring Alzheimer's Disease
  • Comprises Apoptosis Membrane Protein (Apo-2) And Monoclonal Antibody Antagonist For Treating Cancer, Cardiovascular And Nervous System Disorders
  • Variants Of Vascular Endothelial Cell Growth Factor
  • Compositions And Methods For Cancer
  • Inhibitor Of Vascular Endothelial Cell Growth Factor
  • Novel Peptide Hormones With Calcitonin-Like Activity
  • Compositions Comprising Purified Anti-Abeta Monoclonal Antibodies
  • Used To Modulate P-Rb (Retinoblastoma Susceptibility Gene Product)-Protein Interactions, For Cancer Analysis And Treatment By Controlling Cell Growth And Proliferation
  • Apo-2 Ligand
  • Systems And Methods For Breast Cancer Detection And Risk Assessment
  • Cancer Treatment With C-Met Antagonists And Correlation Of The Latter With Hgf Expression
  • Apo-2 Receptor Polynucleotides
  • Methods For Stimulating Hematopoietic Progenitors Using Hepatocyte Growth Factor And Lymphokines
  • Apo-2 Ligand
  • Method And Apparatus To Identify Vulnerable Plaques With Thermal Wave Imaging Of Heated Nanoparticles
  • Compositions Comprising Purified Recombinant Il-13 Antibody
  • Anticancer Agent
  • Amino Acid Sequence Of Native Polypeptide Which Interacts With Hedgehog And Patched Signaling Molecules Involved In Cell Proliferation And Differentiation; For Therapy And Diagnosis
  • Fc Receptor Antibodies And Methods Of Use Thereof
  • Human And Rat Smoothened, Are Provided. Compositions Including Vertebrate Smoothened Chimeras, Nucleic Acid Encoding Vertebrate Smoothened, And Antibodies To Vertebrate Smoothened, Are Also Provided.
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Administering Osteopontin Antisense Oligonucleotide To Inhibit Expression
  • Method Of Enhancing Proliferation Or Differentiation Of Hematopoietic Stem Cells Using Wnt Polypeptides
  • Anti-Htra1 Antibodies And Methods Of Use Thereof
  • Ultrapurified Dsba And Dsbc And Methods Of Making And Using The Same
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Inhibiting C-Met Activation In Subject By Administering An Hgf/C-Met Antagonist Molecule, Wherein The Hgf/C-Met Antagonist Molecule Comprises An Hgf Mutant Comprising A Mutation In Hgf Beta Chain N Terminal Region, Wherein Mutation Is G498i, G498p, G498v, R502del Plus T503del, Or D672n
  • Restoration Of Vasculature After A Myocardial Infarct
  • Methods And Compositions Comprising Purified Recombinant Polypeptides
  • Variants Of Vascular Endothelial Cell Growth Factor, Their Uses, And Processes For Their Production
  • Administering An Effective Amount Of Hepatocyte Growth Factor Receptor Antagonist To A Mammal Diagnosed As Having Cancer, Wherein Said Hepatocyte Growth Factor Receptor Antagonist Is An Antibody
  • Method And Apparatus To Identify Vulnerable Plaques With Thermal Wave Imaging Of Heated Nanoparticles
  • Affinity Enhancement Immunological Reagents For In Vivo Detection And Killing Of Specific Target Cells
  • Methods And Compositions Comprising Purified Recombinant Polypeptides
  • Anti-C-Met-Antibody Formulations
  • Detecting Variations In Mammalian Immunoglobulins; Obtain Immunoglobulins, Compare Variable Domains Of Immunoglobulins, Detect Homogeneity, Detect Variability In Sequence Complementarity Determining Region Of Immunoglobulins
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Compositions And Methods For Detecting And Quantifying Host Cells Protein In Cell Lines And Recombinant Polypeptide Products
  • Method Of Treating Inflammatory Disorder With Antibodies Directed Against Interleukin-33 (Il-33)
  • Apo-2 Ligand
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Apo-3 Polypeptide
  • Anti-Muc16 Antibodies And Uses Thereof
  • Antibodies To Muc16 And Methods Of Use Thereof
  • Nucleic Acids Encoding Hepatocyte Growth Factor Receptor Antagonist Antibodies
  • Bispecific Antibody Constructs And Methods Of Use
  • Uses Of Wnt Polypeptides
  • Hepatocyte Growth Factor Receptor Antagonists And Uses Thereof
  • O-Fucosyltransferase
  • Idiotypic Antibodies And Uses Thereof
  • Nucleic Acids Coding For Adhesion Factors Of Group B Streptococcus, Adhesion Factors Of Group B Streptococcus And Futher Uses Thereof
  • Hepatocyte Growth Factor Receptor Agonists And Uses Thereof
  • Methods Of Screening For Agents Affecting The Deposition Of Β-Amyloid Peptides On Amyloid Plaques In Human Tissue
  • Anti-Cxcr4 Antibodies And Their Use For The Treatment Of Cancer
  • Icos Ligand Variant Immunomodulatory Proteins And Uses Thereof
  • Compositions And Methods For Detecting And Quantifying Host Cell Protein In Cell Lines And Recombinant Polypeptide Products
  • Magneto-Motive Ultrasound Detection Of Magnetic Nanoparticles
  • Humanized Anti Cxcr4 Antibodies For The Treatment Of Cancer
  • Humanized Antibodies Which Bind To Human April (“A Proliferation-Inducing Ligand”)
  • Humanized Anti Cxcr4 Antibodies For The Treatment Of Cancer
  • Compositions And Methods In Cancer Associated With Altered Expression Of Kcnj9
  • Compositions And Methods For Detecting And Quantifying Host Cell Protein In Cell Lines And Recombinant Polypeptide Products
  • Magneto-Motive Ultrasound Detection Of Magnetic Nanoparticles
  • Methods For Detection Of Breast Cancer
  • Antibodies Directed Against T Cell Immunoglobulin And Mucin Protein 3 (Tim-3)
  • Compositions And Methods In Cancer Associated With Altered Expression Of Prlr
  • Non-Small Cell Lung, Colon, Colorectal, Lymphoma, Pancreatic Or Ovarian Cancer
  • Immunoglobulins Which Bind Preferential Mammalian Polypeptide; For The Treatment Of Cancer; Anticarcinogenic Agents
  • Binding Members For Human C-Maf
  • Apo-2 Receptor Agonist Antibodies
  • Cd80 Variant Immunomodulatory Proteins And Uses Thereof
  • Flt4 (Vegfr-3) As A Target For Tumor Imaging And Anti-Tumor Therapy
  • Method Of Treatment Comprising Purified Recombinant Il-13 Antibody
  • Hgf Β Chain Variants
  • Using Hepatocyte Growth Factor And Protein
  • Icos Ligand Variant Immunomodulatory Proteins And Uses Thereof
  • Anti-Cxcr4 Antibodies And Their Use For The Treatment Of Cancer
  • Chimeric Fibroblast Growth Factors With Altered Receptor Specificity
  • Methods Of Screening For Agents Affecting The Deposition Of Β-Amyloid Peptides On Amyloid Plaques In Human Tissue
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/194495a0

    DOI

    http://dx.doi.org/10.1038/194495a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1006221676

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14450081


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "author": [
          {
            "affiliation": {
              "alternateName": "Division of Chemistry and Biochemistry, Imperial Cancer Research Fund, Lincoln's Inn Fields, W.C.2, London", 
              "id": "http://www.grid.ac/institutes/grid.11485.39", 
              "name": [
                "Division of Chemistry and Biochemistry, Imperial Cancer Research Fund, Lincoln's Inn Fields, W.C.2, London"
              ], 
              "type": "Organization"
            }, 
            "familyName": "HUNTER", 
            "givenName": "W. M.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Chemistry and Biochemistry, Imperial Cancer Research Fund, Lincoln's Inn Fields, W.C.2, London", 
              "id": "http://www.grid.ac/institutes/grid.11485.39", 
              "name": [
                "Division of Chemistry and Biochemistry, Imperial Cancer Research Fund, Lincoln's Inn Fields, W.C.2, London"
              ], 
              "type": "Organization"
            }, 
            "familyName": "GREENWOOD", 
            "givenName": "F. C.", 
            "id": "sg:person.0105721045.60", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105721045.60"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/1901211a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052322294", 
              "https://doi.org/10.1038/1901211a0"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1962-05", 
        "datePublishedReg": "1962-05-01", 
        "description": "RECENT procedures for the immunological assay of protein hormones in human plasma1\u20133 require the routine preparation of hormones labelled with iodine-131 of high specific activity.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/194495a0", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0028-0836", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "4827", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "194"
          }
        ], 
        "keywords": [
          "human growth hormone", 
          "growth hormone", 
          "iodine-131", 
          "protein hormones", 
          "hormone", 
          "immunological assays", 
          "high specific activity", 
          "specific activity", 
          "routine preparation", 
          "recent procedure", 
          "activity", 
          "assays", 
          "procedure", 
          "preparation"
        ], 
        "name": "Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity", 
        "pagination": "495-496", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1006221676"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/194495a0"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "14450081"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/194495a0", 
          "https://app.dimensions.ai/details/publication/pub.1006221676"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T16:05", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_85.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/194495a0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/194495a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/194495a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/194495a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/194495a0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    77 TRIPLES      20 PREDICATES      39 URIs      32 LITERALS      7 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/194495a0 schema:author N219f79e9ff244aefb31091bf1190ee1e
    2 schema:citation sg:pub.10.1038/1901211a0
    3 schema:datePublished 1962-05
    4 schema:datePublishedReg 1962-05-01
    5 schema:description RECENT procedures for the immunological assay of protein hormones in human plasma1–3 require the routine preparation of hormones labelled with iodine-131 of high specific activity.
    6 schema:genre article
    7 schema:isAccessibleForFree false
    8 schema:isPartOf N723d83bf94ab497dacdde27a48486241
    9 Nac843b05f83a48c79f6b2d45c2a6b7c1
    10 sg:journal.1018957
    11 schema:keywords activity
    12 assays
    13 growth hormone
    14 high specific activity
    15 hormone
    16 human growth hormone
    17 immunological assays
    18 iodine-131
    19 preparation
    20 procedure
    21 protein hormones
    22 recent procedure
    23 routine preparation
    24 specific activity
    25 schema:name Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity
    26 schema:pagination 495-496
    27 schema:productId N2198d59c8d2947ec8ea687266366d80f
    28 Na962d707219b4caf96c45800116112c1
    29 Nf8454f0830514671923feea9241e935d
    30 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006221676
    31 https://doi.org/10.1038/194495a0
    32 schema:sdDatePublished 2022-09-02T16:05
    33 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    34 schema:sdPublisher Nb223c422ad694b28bbc2a1b954d3abd0
    35 schema:url https://doi.org/10.1038/194495a0
    36 sgo:license sg:explorer/license/
    37 sgo:sdDataset articles
    38 rdf:type schema:ScholarlyArticle
    39 N2198d59c8d2947ec8ea687266366d80f schema:name dimensions_id
    40 schema:value pub.1006221676
    41 rdf:type schema:PropertyValue
    42 N219f79e9ff244aefb31091bf1190ee1e rdf:first N8a7f9de012174af5a99f5ffe41102297
    43 rdf:rest N923336c7fe4a495d8b390765feebb031
    44 N723d83bf94ab497dacdde27a48486241 schema:issueNumber 4827
    45 rdf:type schema:PublicationIssue
    46 N8a7f9de012174af5a99f5ffe41102297 schema:affiliation grid-institutes:grid.11485.39
    47 schema:familyName HUNTER
    48 schema:givenName W. M.
    49 rdf:type schema:Person
    50 N923336c7fe4a495d8b390765feebb031 rdf:first sg:person.0105721045.60
    51 rdf:rest rdf:nil
    52 Na962d707219b4caf96c45800116112c1 schema:name doi
    53 schema:value 10.1038/194495a0
    54 rdf:type schema:PropertyValue
    55 Nac843b05f83a48c79f6b2d45c2a6b7c1 schema:volumeNumber 194
    56 rdf:type schema:PublicationVolume
    57 Nb223c422ad694b28bbc2a1b954d3abd0 schema:name Springer Nature - SN SciGraph project
    58 rdf:type schema:Organization
    59 Nf8454f0830514671923feea9241e935d schema:name pubmed_id
    60 schema:value 14450081
    61 rdf:type schema:PropertyValue
    62 sg:journal.1018957 schema:issn 0028-0836
    63 1476-4687
    64 schema:name Nature
    65 schema:publisher Springer Nature
    66 rdf:type schema:Periodical
    67 sg:person.0105721045.60 schema:affiliation grid-institutes:grid.11485.39
    68 schema:familyName GREENWOOD
    69 schema:givenName F. C.
    70 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105721045.60
    71 rdf:type schema:Person
    72 sg:pub.10.1038/1901211a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052322294
    73 https://doi.org/10.1038/1901211a0
    74 rdf:type schema:CreativeWork
    75 grid-institutes:grid.11485.39 schema:alternateName Division of Chemistry and Biochemistry, Imperial Cancer Research Fund, Lincoln's Inn Fields, W.C.2, London
    76 schema:name Division of Chemistry and Biochemistry, Imperial Cancer Research Fund, Lincoln's Inn Fields, W.C.2, London
    77 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...