Genetic Basis for Graft-against-Host Immunological Reactions between Two Inbred Lines of Chickens View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1961-04

AUTHORS

L. N. PAYNE, P. JAFFE

ABSTRACT

IT has been established that the enlargement of the embryonic spleen which follows the injection of adult chicken blood into chick embryos is due, at least in part, to a proliferation of cells derived from the injected blood1,2. Cock and Simonsen3 have shown that virtually no splenic enlargement occurs when the blood-donor and embryonic recipients are members of the same inbred line of chickens. The phenomenon of splenic enlargement seems to be fundamentally immunological in nature, and due to donor cells proliferating in response to those host antigens which differ from any in the donor. More... »

PAGES

373-374

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/190373a0

DOI

http://dx.doi.org/10.1038/190373a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041088075

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/13733674


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