Estimation of 3-Deoxy Sugars by Means of the Malonaldehyde–Thiobarbituric Acid Reaction View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1960-04

AUTHORS

MORRIS A. CYNKIN, GILBERT ASHWELL

ABSTRACT

DURING the course of our investigations on the biosynthesis of 3,6-dideoxy-hexoses, found in the endotoxins of Salmonella and Escherichia1–3 and in the eggs of Parascaris equorum4, the need arose for a sensitive and specific assay. A consideration of the structures of these compounds suggested to us that the malonaldehyde–thiobarbituric acid reaction, which was adapted by Waravdekar and Saslaw5 for the estimation of 2-deoxy-ribose, might equally be applicable to the quantitative determination of 3,6-dideoxy-hexoses, and indeed, of 3-deoxy sugars in general. A sample of ascarylose (3,6-dideoxy-L-arabino-hexose), which was the generous gift of Dr. E. Lederer, was used to test this hypothesis. More... »

PAGES

155-156

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/186155a0

DOI

http://dx.doi.org/10.1038/186155a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034784030

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/13813473


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