Asymmetrical Recombination of Alkali-dissociated Hæmoglobin Mixtures View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1960-02

AUTHORS

ELIZABETH ROBINSON, HARVEY A. ITANO

ABSTRACT

THE human adult hæmoglobins and canine hæmoglobin recombine asymmetrically, that is: after both short and prolonged exposure to dilute acid1–5. At pH. 11, hæmoglobin A dissociates into half-molecules6; furthermore, re-association of a mixture of labelled hæmoglobin S and hæmoglobin A after 24 hr. at pH. 11 results in the exchange of the β2 sub-units7. We now wish to report a series of experiments which indicate that hæmoglobin also recombines asymmetrically after short exposure to alkali. More... »

PAGES

547-549

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/185547b0

DOI

http://dx.doi.org/10.1038/185547b0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050423621

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18990777


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Alkalies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carboxyhemoglobin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hemoglobins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrogen-Ion Concentration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombination, Genetic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland", 
          "id": "http://www.grid.ac/institutes/grid.94365.3d", 
          "name": [
            "National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "ROBINSON", 
        "givenName": "ELIZABETH", 
        "id": "sg:person.057532766.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.057532766.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland", 
          "id": "http://www.grid.ac/institutes/grid.94365.3d", 
          "name": [
            "National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "ITANO", 
        "givenName": "HARVEY A.", 
        "id": "sg:person.01266611511.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266611511.24"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/1831799a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031426687", 
          "https://doi.org/10.1038/1831799a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/1841468a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024366074", 
          "https://doi.org/10.1038/1841468a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1960-02", 
    "datePublishedReg": "1960-02-01", 
    "description": "THE human adult h\u00e6moglobins and canine h\u00e6moglobin recombine asymmetrically, that is:  after both short and prolonged exposure to dilute acid1\u20135. At pH. 11, h\u00e6moglobin A dissociates into half-molecules6; furthermore, re-association of a mixture of labelled h\u00e6moglobin S and h\u00e6moglobin A after 24 hr. at pH. 11 results in the exchange of the \u03b22 sub-units7. We now wish to report a series of experiments which indicate that h\u00e6moglobin also recombines asymmetrically after short exposure to alkali.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/185547b0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4712", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "185"
      }
    ], 
    "keywords": [
      "prolonged exposure", 
      "short exposure", 
      "exposure", 
      "hr", 
      "h\u00e6moglobin", 
      "series of experiments", 
      "sub", 
      "series", 
      "results", 
      "re-association", 
      "experiments", 
      "mixture", 
      "exchange", 
      "recombination", 
      "alkali", 
      "recombines"
    ], 
    "name": "Asymmetrical Recombination of Alkali-dissociated H\u00e6moglobin Mixtures", 
    "pagination": "547-549", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050423621"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/185547b0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18990777"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/185547b0", 
      "https://app.dimensions.ai/details/publication/pub.1050423621"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:44", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_105.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/185547b0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/185547b0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/185547b0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/185547b0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/185547b0'


 

This table displays all metadata directly associated to this object as RDF triples.

112 TRIPLES      21 PREDICATES      49 URIs      39 LITERALS      12 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/185547b0 schema:about N07d06e670c8248d5a73b3c25dddf9464
2 N355ef7c83be54459a5c7e9b4792fa6ed
3 N64f4ac799e014fdf866c9b221143d651
4 Na0121066b4564190a1206dffa761bc97
5 Ne96946521c574fbaa35a94e5836ee507
6 anzsrc-for:11
7 anzsrc-for:1117
8 schema:author N89dc2c3e7b484c78a697375b6542a138
9 schema:citation sg:pub.10.1038/1831799a0
10 sg:pub.10.1038/1841468a0
11 schema:datePublished 1960-02
12 schema:datePublishedReg 1960-02-01
13 schema:description THE human adult hæmoglobins and canine hæmoglobin recombine asymmetrically, that is: after both short and prolonged exposure to dilute acid1–5. At pH. 11, hæmoglobin A dissociates into half-molecules6; furthermore, re-association of a mixture of labelled hæmoglobin S and hæmoglobin A after 24 hr. at pH. 11 results in the exchange of the β2 sub-units7. We now wish to report a series of experiments which indicate that hæmoglobin also recombines asymmetrically after short exposure to alkali.
14 schema:genre article
15 schema:isAccessibleForFree false
16 schema:isPartOf N23093232b2014c73ab7748e85e90a4ed
17 Nf5aa620a4a5941e2a26487f36e521b72
18 sg:journal.1018957
19 schema:keywords alkali
20 exchange
21 experiments
22 exposure
23 hr
24 hæmoglobin
25 mixture
26 prolonged exposure
27 re-association
28 recombination
29 recombines
30 results
31 series
32 series of experiments
33 short exposure
34 sub
35 schema:name Asymmetrical Recombination of Alkali-dissociated Hæmoglobin Mixtures
36 schema:pagination 547-549
37 schema:productId N352a7e9a543940779857360a4b70c31d
38 Ncd63c4ff404b485e8030d2d2a59afc50
39 Nee199d568998406aab3bf3713e163d7b
40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050423621
41 https://doi.org/10.1038/185547b0
42 schema:sdDatePublished 2022-09-02T15:44
43 schema:sdLicense https://scigraph.springernature.com/explorer/license/
44 schema:sdPublisher N8a8ce3294dde4bc0ac145b01334b2071
45 schema:url https://doi.org/10.1038/185547b0
46 sgo:license sg:explorer/license/
47 sgo:sdDataset articles
48 rdf:type schema:ScholarlyArticle
49 N07d06e670c8248d5a73b3c25dddf9464 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
50 schema:name Carboxyhemoglobin
51 rdf:type schema:DefinedTerm
52 N23093232b2014c73ab7748e85e90a4ed schema:volumeNumber 185
53 rdf:type schema:PublicationVolume
54 N352a7e9a543940779857360a4b70c31d schema:name dimensions_id
55 schema:value pub.1050423621
56 rdf:type schema:PropertyValue
57 N355ef7c83be54459a5c7e9b4792fa6ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
58 schema:name Alkalies
59 rdf:type schema:DefinedTerm
60 N64f4ac799e014fdf866c9b221143d651 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
61 schema:name Hemoglobins
62 rdf:type schema:DefinedTerm
63 N89dc2c3e7b484c78a697375b6542a138 rdf:first sg:person.057532766.38
64 rdf:rest Nb1600628833e40058a807e4fa5bb75fe
65 N8a8ce3294dde4bc0ac145b01334b2071 schema:name Springer Nature - SN SciGraph project
66 rdf:type schema:Organization
67 Na0121066b4564190a1206dffa761bc97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Hydrogen-Ion Concentration
69 rdf:type schema:DefinedTerm
70 Nb1600628833e40058a807e4fa5bb75fe rdf:first sg:person.01266611511.24
71 rdf:rest rdf:nil
72 Ncd63c4ff404b485e8030d2d2a59afc50 schema:name pubmed_id
73 schema:value 18990777
74 rdf:type schema:PropertyValue
75 Ne96946521c574fbaa35a94e5836ee507 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Recombination, Genetic
77 rdf:type schema:DefinedTerm
78 Nee199d568998406aab3bf3713e163d7b schema:name doi
79 schema:value 10.1038/185547b0
80 rdf:type schema:PropertyValue
81 Nf5aa620a4a5941e2a26487f36e521b72 schema:issueNumber 4712
82 rdf:type schema:PublicationIssue
83 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
84 schema:name Medical and Health Sciences
85 rdf:type schema:DefinedTerm
86 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
87 schema:name Public Health and Health Services
88 rdf:type schema:DefinedTerm
89 sg:journal.1018957 schema:issn 0028-0836
90 1476-4687
91 schema:name Nature
92 schema:publisher Springer Nature
93 rdf:type schema:Periodical
94 sg:person.01266611511.24 schema:affiliation grid-institutes:grid.94365.3d
95 schema:familyName ITANO
96 schema:givenName HARVEY A.
97 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266611511.24
98 rdf:type schema:Person
99 sg:person.057532766.38 schema:affiliation grid-institutes:grid.94365.3d
100 schema:familyName ROBINSON
101 schema:givenName ELIZABETH
102 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.057532766.38
103 rdf:type schema:Person
104 sg:pub.10.1038/1831799a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031426687
105 https://doi.org/10.1038/1831799a0
106 rdf:type schema:CreativeWork
107 sg:pub.10.1038/1841468a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024366074
108 https://doi.org/10.1038/1841468a0
109 rdf:type schema:CreativeWork
110 grid-institutes:grid.94365.3d schema:alternateName National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland
111 schema:name National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland
112 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...