Post-activation Changes at the Mammalian Neuromuscular Junction View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1959-12

AUTHORS

J. I. HUBBARD

ABSTRACT

AN attractive explanation of the post-activation potentiation found at the neuromuscular junction is that the presynaptic impulse, in addition to producing a momentary synchronous release of miniature potentials—the endplate potential—causes mobilization of further transmitter signalled by an increase in the frequency of the spontaneous miniature discharge1. This hypothesis, if confirmed, would be of great importance in understanding the mechanism of transmitter release. It has therefore been investigated by studying changes in the frequencies of the miniature potential and in the size of the parallel endplate potential after conditioning by one to five thousand volleys, using a wide range of stimulating frequencies. More... »

PAGES

1945-1947

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/1841945a0

DOI

http://dx.doi.org/10.1038/1841945a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021117221

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/14403666


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