Pseudocholinesterase in Pacinian Corpuscles View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1955-04

AUTHORS

CATHERINE HEBB, KENNETH J. HILL

ABSTRACT

WE have recently studied the distribution of cholinesterases in the cat's pancreas by Koelle's histochemical method1, and observed that among other structures which contain enzyme the Pacinian corpuscles are prominent. The cholinesterase was seen to be concentrated in the core and stalk of this sensory organ (Fig. 1). By the use of appropriate substrates (acetyl- and butyryl-thiocholine) and a selective inhibitor (diisopropyl-fluoro-phosphate) the enzyme has been identified as pseudocholinesterase. Although the Pacinian corpuscles found in this situation are not pancreatic structures, being part of the enfolding mesentery, their location here is convenient because it is easier to section them when supported by the glandular tissue than when they are lying free in the mesentery. More... »

PAGES

597-597

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/175597a0

DOI

http://dx.doi.org/10.1038/175597a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004511218

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/14370179


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Butyrylcholinesterase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholinesterases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nerve Endings", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pacinian Corpuscles", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Agricultural Research Council Institute of Animal Physiology, Babraham Hall, Babraham, Cambridge", 
          "id": "http://www.grid.ac/institutes/grid.418195.0", 
          "name": [
            "Agricultural Research Council Institute of Animal Physiology, Babraham Hall, Babraham, Cambridge"
          ], 
          "type": "Organization"
        }, 
        "familyName": "HEBB", 
        "givenName": "CATHERINE", 
        "id": "sg:person.054224774.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.054224774.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Agricultural Research Council Institute of Animal Physiology, Babraham Hall, Babraham, Cambridge", 
          "id": "http://www.grid.ac/institutes/grid.418195.0", 
          "name": [
            "Agricultural Research Council Institute of Animal Physiology, Babraham Hall, Babraham, Cambridge"
          ], 
          "type": "Organization"
        }, 
        "familyName": "HILL", 
        "givenName": "KENNETH J.", 
        "type": "Person"
      }
    ], 
    "datePublished": "1955-04", 
    "datePublishedReg": "1955-04-01", 
    "description": "WE have recently studied the distribution of cholinesterases in the cat's pancreas by Koelle's histochemical method1, and observed that among other structures which contain enzyme the Pacinian corpuscles are prominent. The cholinesterase was seen to be concentrated in the core and stalk of this sensory organ (Fig. 1). By the use of appropriate substrates (acetyl- and butyryl-thiocholine) and a selective inhibitor (diisopropyl-fluoro-phosphate) the enzyme has been identified as pseudocholinesterase. Although the Pacinian corpuscles found in this situation are not pancreatic structures, being part of the enfolding mesentery, their location here is convenient because it is easier to section them when supported by the glandular tissue than when they are lying free in the mesentery.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/175597a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4457", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "175"
      }
    ], 
    "keywords": [
      "sensory organs", 
      "selective inhibitor", 
      "enzyme", 
      "appropriate substrate", 
      "distribution of cholinesterases", 
      "stalk", 
      "inhibitors", 
      "cat pancreas", 
      "tissue", 
      "organs", 
      "cholinesterase", 
      "substrate", 
      "structure", 
      "pancreatic structure", 
      "corpuscles", 
      "glandular tissue", 
      "pseudocholinesterase", 
      "pancreas", 
      "distribution", 
      "location", 
      "part", 
      "Pacinian corpuscles", 
      "core", 
      "mesentery", 
      "use", 
      "situation", 
      "method1"
    ], 
    "name": "Pseudocholinesterase in Pacinian Corpuscles", 
    "pagination": "597-597", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1004511218"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/175597a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "14370179"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/175597a0", 
      "https://app.dimensions.ai/details/publication/pub.1004511218"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:41", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_68.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/175597a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/175597a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/175597a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/175597a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/175597a0'


 

This table displays all metadata directly associated to this object as RDF triples.

110 TRIPLES      20 PREDICATES      57 URIs      49 LITERALS      11 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/175597a0 schema:about N0dc2cbeca6ea4a70a79142f93c749872
2 N7848636e0c374c618be1417b19431177
3 N9710b36b5671419fa0a61fcd23a5c939
4 Na3e9868efdb74f3e81b9b2e37acedb77
5 anzsrc-for:06
6 anzsrc-for:0601
7 schema:author N99e10334d973455c921c1d748b4ae333
8 schema:datePublished 1955-04
9 schema:datePublishedReg 1955-04-01
10 schema:description WE have recently studied the distribution of cholinesterases in the cat's pancreas by Koelle's histochemical method1, and observed that among other structures which contain enzyme the Pacinian corpuscles are prominent. The cholinesterase was seen to be concentrated in the core and stalk of this sensory organ (Fig. 1). By the use of appropriate substrates (acetyl- and butyryl-thiocholine) and a selective inhibitor (diisopropyl-fluoro-phosphate) the enzyme has been identified as pseudocholinesterase. Although the Pacinian corpuscles found in this situation are not pancreatic structures, being part of the enfolding mesentery, their location here is convenient because it is easier to section them when supported by the glandular tissue than when they are lying free in the mesentery.
11 schema:genre article
12 schema:isAccessibleForFree false
13 schema:isPartOf N0081e7b93ab14fab9696a88254695996
14 N0357822eaecd4eedbfe7635857c0ae9f
15 sg:journal.1018957
16 schema:keywords Pacinian corpuscles
17 appropriate substrate
18 cat pancreas
19 cholinesterase
20 core
21 corpuscles
22 distribution
23 distribution of cholinesterases
24 enzyme
25 glandular tissue
26 inhibitors
27 location
28 mesentery
29 method1
30 organs
31 pancreas
32 pancreatic structure
33 part
34 pseudocholinesterase
35 selective inhibitor
36 sensory organs
37 situation
38 stalk
39 structure
40 substrate
41 tissue
42 use
43 schema:name Pseudocholinesterase in Pacinian Corpuscles
44 schema:pagination 597-597
45 schema:productId N1192e876d0d246eba8f602973c898ad5
46 N50e8bb1b1ed84ca5b6c466aa7d9af8c4
47 Nf70c85d4f76e43e3b4f06b97c07d7a21
48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004511218
49 https://doi.org/10.1038/175597a0
50 schema:sdDatePublished 2022-10-01T06:41
51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
52 schema:sdPublisher N9ff8db7861e6449ea346aa2e964eade2
53 schema:url https://doi.org/10.1038/175597a0
54 sgo:license sg:explorer/license/
55 sgo:sdDataset articles
56 rdf:type schema:ScholarlyArticle
57 N0081e7b93ab14fab9696a88254695996 schema:volumeNumber 175
58 rdf:type schema:PublicationVolume
59 N0357822eaecd4eedbfe7635857c0ae9f schema:issueNumber 4457
60 rdf:type schema:PublicationIssue
61 N0dc2cbeca6ea4a70a79142f93c749872 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Butyrylcholinesterase
63 rdf:type schema:DefinedTerm
64 N1192e876d0d246eba8f602973c898ad5 schema:name pubmed_id
65 schema:value 14370179
66 rdf:type schema:PropertyValue
67 N20e21a411dbc4979be65815d7ff21b20 rdf:first Naa8f17d36f2849539051f7445c450f58
68 rdf:rest rdf:nil
69 N50e8bb1b1ed84ca5b6c466aa7d9af8c4 schema:name doi
70 schema:value 10.1038/175597a0
71 rdf:type schema:PropertyValue
72 N7848636e0c374c618be1417b19431177 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Cholinesterases
74 rdf:type schema:DefinedTerm
75 N9710b36b5671419fa0a61fcd23a5c939 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Pacinian Corpuscles
77 rdf:type schema:DefinedTerm
78 N99e10334d973455c921c1d748b4ae333 rdf:first sg:person.054224774.49
79 rdf:rest N20e21a411dbc4979be65815d7ff21b20
80 N9ff8db7861e6449ea346aa2e964eade2 schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 Na3e9868efdb74f3e81b9b2e37acedb77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Nerve Endings
84 rdf:type schema:DefinedTerm
85 Naa8f17d36f2849539051f7445c450f58 schema:affiliation grid-institutes:grid.418195.0
86 schema:familyName HILL
87 schema:givenName KENNETH J.
88 rdf:type schema:Person
89 Nf70c85d4f76e43e3b4f06b97c07d7a21 schema:name dimensions_id
90 schema:value pub.1004511218
91 rdf:type schema:PropertyValue
92 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
93 schema:name Biological Sciences
94 rdf:type schema:DefinedTerm
95 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
96 schema:name Biochemistry and Cell Biology
97 rdf:type schema:DefinedTerm
98 sg:journal.1018957 schema:issn 0028-0836
99 1476-4687
100 schema:name Nature
101 schema:publisher Springer Nature
102 rdf:type schema:Periodical
103 sg:person.054224774.49 schema:affiliation grid-institutes:grid.418195.0
104 schema:familyName HEBB
105 schema:givenName CATHERINE
106 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.054224774.49
107 rdf:type schema:Person
108 grid-institutes:grid.418195.0 schema:alternateName Agricultural Research Council Institute of Animal Physiology, Babraham Hall, Babraham, Cambridge
109 schema:name Agricultural Research Council Institute of Animal Physiology, Babraham Hall, Babraham, Cambridge
110 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...