Recombination in Bacteria: Outcrossing Escherichia coli K 12 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1949-12

AUTHORS

L. L. CAVALLI, H. HESLOT

ABSTRACT

THE discovery of recombination in Escherichia coli1,2 has given to bacterial genetics a much wider scope than it had before. Three years after its first publication, however, the results obtained by Leder-berg with the strain known as K 12 still stand alone, no other bacterial strain having been found to show a similar behaviour. This is partly due to the fact that demonstration of recombination is a slow business, owing to the work required for the preparation of suitable substrains. In fact, the only method known so far is still the original one of mixing substrains having different growth requirements on a minimal medium where neither parental strain can grow, but on which cells possessing some of the synthetic capacities of one strain and some of the other will be able to form colonies. As such colonies, called by Lederberg 'prototrophs', usually appear at a very low rate, care must be taken that recombination is not simulated by back-mutation in either parental strain. More... »

PAGES

1057-1058

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/1641057c0

DOI

http://dx.doi.org/10.1038/1641057c0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034297128

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15397435


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0605", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Escherichia coli", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombination, Genetic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Genetics, University, Cambridge", 
          "id": "http://www.grid.ac/institutes/grid.5335.0", 
          "name": [
            "Department of Genetics, University, Cambridge"
          ], 
          "type": "Organization"
        }, 
        "familyName": "CAVALLI", 
        "givenName": "L. L.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Genetics, University, Cambridge", 
          "id": "http://www.grid.ac/institutes/grid.5335.0", 
          "name": [
            "Department of Genetics, University, Cambridge"
          ], 
          "type": "Organization"
        }, 
        "familyName": "HESLOT", 
        "givenName": "H.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/158558a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020814070", 
          "https://doi.org/10.1038/158558a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1949-12", 
    "datePublishedReg": "1949-12-01", 
    "description": "THE discovery of recombination in Escherichia coli1,2 has given to bacterial genetics a much wider scope than it had before. Three years after its first publication, however, the results obtained by Leder-berg with the strain known as K 12 still stand alone, no other bacterial strain having been found to show a similar behaviour. This is partly due to the fact that demonstration of recombination is a slow business, owing to the work required for the preparation of suitable substrains. In fact, the only method known so far is still the original one of mixing substrains having different growth requirements on a minimal medium where neither parental strain can grow, but on which cells possessing some of the synthetic capacities of one strain and some of the other will be able to form colonies. As such colonies, called by Lederberg 'prototrophs', usually appear at a very low rate, care must be taken that recombination is not simulated by back-mutation in either parental strain.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/1641057c0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4181", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "164"
      }
    ], 
    "keywords": [
      "strains", 
      "substrains", 
      "only method", 
      "different growth requirements", 
      "parental strain", 
      "synthetic capacity", 
      "lower rates", 
      "care", 
      "discovery", 
      "Escherichia", 
      "bacterial genetics", 
      "genetics", 
      "years", 
      "first publication", 
      "publications", 
      "bacterial strains", 
      "demonstration", 
      "preparation", 
      "growth requirements", 
      "minimal medium", 
      "cells", 
      "colonies", 
      "such colonies", 
      "rate", 
      "bacteria", 
      "Escherichia coli K 12", 
      "coli K 12", 
      "recombination", 
      "wide scope", 
      "scope", 
      "results", 
      "behavior", 
      "fact", 
      "work", 
      "method", 
      "requirements", 
      "medium", 
      "capacity", 
      "prototrophs", 
      "similar behavior", 
      "business"
    ], 
    "name": "Recombination in Bacteria: Outcrossing Escherichia coli K 12", 
    "pagination": "1057-1058", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034297128"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/1641057c0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15397435"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/1641057c0", 
      "https://app.dimensions.ai/details/publication/pub.1034297128"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T09:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_47.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/1641057c0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/1641057c0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/1641057c0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/1641057c0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/1641057c0'


 

This table displays all metadata directly associated to this object as RDF triples.

123 TRIPLES      21 PREDICATES      71 URIs      62 LITERALS      10 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/1641057c0 schema:about N071655e5357a465d8c26c6c8d6fd30d0
2 N598d5c9db7fa4296b3d84e2f3955c707
3 N85247148de754114a176d784e6ae535c
4 anzsrc-for:06
5 anzsrc-for:0605
6 schema:author N97e2a9a7a7f943009debece753a4bc2b
7 schema:citation sg:pub.10.1038/158558a0
8 schema:datePublished 1949-12
9 schema:datePublishedReg 1949-12-01
10 schema:description THE discovery of recombination in Escherichia coli1,2 has given to bacterial genetics a much wider scope than it had before. Three years after its first publication, however, the results obtained by Leder-berg with the strain known as K 12 still stand alone, no other bacterial strain having been found to show a similar behaviour. This is partly due to the fact that demonstration of recombination is a slow business, owing to the work required for the preparation of suitable substrains. In fact, the only method known so far is still the original one of mixing substrains having different growth requirements on a minimal medium where neither parental strain can grow, but on which cells possessing some of the synthetic capacities of one strain and some of the other will be able to form colonies. As such colonies, called by Lederberg 'prototrophs', usually appear at a very low rate, care must be taken that recombination is not simulated by back-mutation in either parental strain.
11 schema:genre article
12 schema:isAccessibleForFree false
13 schema:isPartOf Nce0f450f2c0b483ba5a73c138ea03f47
14 Ndf5cc5c12dda41c9bef67b2e18603dbe
15 sg:journal.1018957
16 schema:keywords Escherichia
17 Escherichia coli K 12
18 bacteria
19 bacterial genetics
20 bacterial strains
21 behavior
22 business
23 capacity
24 care
25 cells
26 coli K 12
27 colonies
28 demonstration
29 different growth requirements
30 discovery
31 fact
32 first publication
33 genetics
34 growth requirements
35 lower rates
36 medium
37 method
38 minimal medium
39 only method
40 parental strain
41 preparation
42 prototrophs
43 publications
44 rate
45 recombination
46 requirements
47 results
48 scope
49 similar behavior
50 strains
51 substrains
52 such colonies
53 synthetic capacity
54 wide scope
55 work
56 years
57 schema:name Recombination in Bacteria: Outcrossing Escherichia coli K 12
58 schema:pagination 1057-1058
59 schema:productId N08ee6b71178247eda71258539bef0086
60 N1367e3bb504f4cc184a3ae833676d9d1
61 N7dabc7e6acc24f0fb67e5b8c6a436efe
62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034297128
63 https://doi.org/10.1038/1641057c0
64 schema:sdDatePublished 2022-05-10T09:57
65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
66 schema:sdPublisher Nba22afa73ab8417cba2ec91962ae0388
67 schema:url https://doi.org/10.1038/1641057c0
68 sgo:license sg:explorer/license/
69 sgo:sdDataset articles
70 rdf:type schema:ScholarlyArticle
71 N071655e5357a465d8c26c6c8d6fd30d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Escherichia coli
73 rdf:type schema:DefinedTerm
74 N08ee6b71178247eda71258539bef0086 schema:name dimensions_id
75 schema:value pub.1034297128
76 rdf:type schema:PropertyValue
77 N1367e3bb504f4cc184a3ae833676d9d1 schema:name doi
78 schema:value 10.1038/1641057c0
79 rdf:type schema:PropertyValue
80 N1c7483c9d8974c90afb755720af00cdd schema:affiliation grid-institutes:grid.5335.0
81 schema:familyName CAVALLI
82 schema:givenName L. L.
83 rdf:type schema:Person
84 N598d5c9db7fa4296b3d84e2f3955c707 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Bacteria
86 rdf:type schema:DefinedTerm
87 N675dd7f7ccde48e993e640f4cfc8a318 schema:affiliation grid-institutes:grid.5335.0
88 schema:familyName HESLOT
89 schema:givenName H.
90 rdf:type schema:Person
91 N7dabc7e6acc24f0fb67e5b8c6a436efe schema:name pubmed_id
92 schema:value 15397435
93 rdf:type schema:PropertyValue
94 N8377b98158fc4cccb75ea91c20803db3 rdf:first N675dd7f7ccde48e993e640f4cfc8a318
95 rdf:rest rdf:nil
96 N85247148de754114a176d784e6ae535c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Recombination, Genetic
98 rdf:type schema:DefinedTerm
99 N97e2a9a7a7f943009debece753a4bc2b rdf:first N1c7483c9d8974c90afb755720af00cdd
100 rdf:rest N8377b98158fc4cccb75ea91c20803db3
101 Nba22afa73ab8417cba2ec91962ae0388 schema:name Springer Nature - SN SciGraph project
102 rdf:type schema:Organization
103 Nce0f450f2c0b483ba5a73c138ea03f47 schema:issueNumber 4181
104 rdf:type schema:PublicationIssue
105 Ndf5cc5c12dda41c9bef67b2e18603dbe schema:volumeNumber 164
106 rdf:type schema:PublicationVolume
107 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
108 schema:name Biological Sciences
109 rdf:type schema:DefinedTerm
110 anzsrc-for:0605 schema:inDefinedTermSet anzsrc-for:
111 schema:name Microbiology
112 rdf:type schema:DefinedTerm
113 sg:journal.1018957 schema:issn 0028-0836
114 1476-4687
115 schema:name Nature
116 schema:publisher Springer Nature
117 rdf:type schema:Periodical
118 sg:pub.10.1038/158558a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020814070
119 https://doi.org/10.1038/158558a0
120 rdf:type schema:CreativeWork
121 grid-institutes:grid.5335.0 schema:alternateName Department of Genetics, University, Cambridge
122 schema:name Department of Genetics, University, Cambridge
123 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...