Effects of Acute Lorazepam Administration on Aminergic Activity in Normal Elderly Subjects: Relationship to Performance Effects and Apolipoprotein Genotype View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-07

AUTHORS

Nunzio Pomara, Lisa M. Willoughby, Audrey Hashim, Henry Sershen, John J. Sidtis, Keith Wesnes, David J. Greenblatt, Abel Lajtha

ABSTRACT

The effects of acute lorazepam challenges on plasma (p) HVA, MHPG, and 5-HIAA, and their relationship to drug-induced cognitive and motor deficits and the apolipoprotein (APOE)-epsilon4 allele were examined. Eighteen healthy elderly (8 epsilon4 carriers) received placebo or acute oral lorazepam doses (0.5 mg or 1 mg) in random sequence, 1-week apart. Cognitive assessment and plasma levels of pHVA, pMHPG, and p5-HIAA were determined at baseline and at 1, 2.5, and 5 h postchallenge. There was no drug-to-placebo difference in monoamine levels and no consistent relationship between changes in monoamine levels and cognitive performance, regardless of epsilon4 status. However, the 1.0 mg dose increased p5-HIAA in epsilon4 carriers, whereas it caused a reduction in noncarriers. Higher baseline pMHPG and p5-HIAA levels were associated with better baseline memory. The epsilon4 allele may modulate the effect of lorazepam on p5-HIAA, but further studies are needed to confirm this finding and elucidate its possible significance. More... »

PAGES

1391-1398

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/b:nere.0000026402.09466.54

DOI

http://dx.doi.org/10.1023/b:nere.0000026402.09466.54

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007802728

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15202770


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1701", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Psychology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/17", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Psychology and Cognitive Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Analysis of Variance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Anxiety Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apolipoprotein E4", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apolipoproteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apolipoproteins E", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cognition", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cognition Disorders", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Homovanillic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxyindoleacetic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lorazepam", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Methoxyhydroxyphenylglycol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Motor Activity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Regression Analysis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "New York University", 
          "id": "https://www.grid.ac/institutes/grid.137628.9", 
          "name": [
            "Geriatric Psychiatry Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York", 
            "Department of Psychiatry, New York University School of Medicine, New York, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pomara", 
        "givenName": "Nunzio", 
        "id": "sg:person.01202107722.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202107722.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New York University", 
          "id": "https://www.grid.ac/institutes/grid.137628.9", 
          "name": [
            "Department of Psychiatry, New York University School of Medicine, New York, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Willoughby", 
        "givenName": "Lisa M.", 
        "id": "sg:person.0756255542.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756255542.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nathan Kline Institute for Psychiatric Research", 
          "id": "https://www.grid.ac/institutes/grid.250263.0", 
          "name": [
            "Center for Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hashim", 
        "givenName": "Audrey", 
        "id": "sg:person.01151027326.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01151027326.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nathan Kline Institute for Psychiatric Research", 
          "id": "https://www.grid.ac/institutes/grid.250263.0", 
          "name": [
            "Center for Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sershen", 
        "givenName": "Henry", 
        "id": "sg:person.01002303570.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002303570.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New York University", 
          "id": "https://www.grid.ac/institutes/grid.137628.9", 
          "name": [
            "Geriatric Psychiatry Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York", 
            "Department of Psychiatry, New York University School of Medicine, New York, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sidtis", 
        "givenName": "John J.", 
        "id": "sg:person.0753230673.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753230673.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Cognitive Treatment Research Ltd., Reading, United Kingdom"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wesnes", 
        "givenName": "Keith", 
        "id": "sg:person.0742373640.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742373640.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tufts University", 
          "id": "https://www.grid.ac/institutes/grid.429997.8", 
          "name": [
            "Department of Pharmacology, Tufts University, Boston, Massachusetts"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Greenblatt", 
        "givenName": "David J.", 
        "id": "sg:person.01353142263.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353142263.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nathan Kline Institute for Psychiatric Research", 
          "id": "https://www.grid.ac/institutes/grid.250263.0", 
          "name": [
            "Department of Psychiatry, New York University School of Medicine, New York, New York", 
            "Center for Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lajtha", 
        "givenName": "Abel", 
        "id": "sg:person.01203017617.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203017617.82"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00501182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001527684", 
          "https://doi.org/10.1007/bf00501182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00501182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001527684", 
          "https://doi.org/10.1007/bf00501182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0091-3057(83)90242-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001894124"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0091-3057(83)90242-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001894124"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0920-9964(91)90056-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002686192"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-1781(96)02886-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003367118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0169-328x(95)00097-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006748224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jnnp.53.10.915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007348276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(88)90179-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014882720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(88)90179-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014882720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0024-3205(01)01158-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017045791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000118574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017558193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0378-4347(00)81896-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018736821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/jpet.300.1.2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021034208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01921910", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021974860", 
          "https://doi.org/10.1007/bf01921910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01921910", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021974860", 
          "https://doi.org/10.1007/bf01921910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archpsyc.1988.01800310072009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022166240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/npp.1994.4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023420159", 
          "https://doi.org/10.1038/npp.1994.4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/npp.1994.4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023420159", 
          "https://doi.org/10.1038/npp.1994.4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(91)90075-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024518153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(91)90075-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024518153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/schbul/18.1.123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026286993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/y83-009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031694016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002826-200007000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032004484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0920-9964(94)90015-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033241083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3223(03)00174-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034278160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3223(03)00174-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034278160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1471-4159.1998.70020708.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034559807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00692778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034795847", 
          "https://doi.org/10.1007/bf00692778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(96)00452-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040480942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(92)91079-t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040928496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(92)91079-t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040928496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0091-3057(95)00177-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044857396"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(95)00269-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047849189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1364-6613(98)01240-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048645815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000119437", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049194203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01243272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052435140", 
          "https://doi.org/10.1007/bf01243272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.pharmtox.38.1.321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052864381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0278-5846(92)90072-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052948072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0278-5846(92)90072-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052948072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00652229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053464066", 
          "https://doi.org/10.1007/bf00652229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-1017399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057488964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-979314", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057508750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004714-199804000-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060188130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004714-199804000-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060188130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004714-199804000-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060188130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077869157", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078691240", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078849190", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1192/s0007125000291733", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079234544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079337654", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083282226", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2004-07", 
    "datePublishedReg": "2004-07-01", 
    "description": "The effects of acute lorazepam challenges on plasma (p) HVA, MHPG, and 5-HIAA, and their relationship to drug-induced cognitive and motor deficits and the apolipoprotein (APOE)-epsilon4 allele were examined. Eighteen healthy elderly (8 epsilon4 carriers) received placebo or acute oral lorazepam doses (0.5 mg or 1 mg) in random sequence, 1-week apart. Cognitive assessment and plasma levels of pHVA, pMHPG, and p5-HIAA were determined at baseline and at 1, 2.5, and 5 h postchallenge. There was no drug-to-placebo difference in monoamine levels and no consistent relationship between changes in monoamine levels and cognitive performance, regardless of epsilon4 status. However, the 1.0 mg dose increased p5-HIAA in epsilon4 carriers, whereas it caused a reduction in noncarriers. Higher baseline pMHPG and p5-HIAA levels were associated with better baseline memory. The epsilon4 allele may modulate the effect of lorazepam on p5-HIAA, but further studies are needed to confirm this finding and elucidate its possible significance.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1023/b:nere.0000026402.09466.54", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2548624", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2446922", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2360787", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1085962", 
        "issn": [
          "0364-3190", 
          "1573-6903"
        ], 
        "name": "Neurochemical Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "29"
      }
    ], 
    "name": "Effects of Acute Lorazepam Administration on Aminergic Activity in Normal Elderly Subjects: Relationship to Performance Effects and Apolipoprotein Genotype", 
    "pagination": "1391-1398", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "252b0536aed7ec45d23afe5aa2fce56aa91ad441e644859ccc4ffc92c1af4ad9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15202770"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7613461"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1023/b:nere.0000026402.09466.54"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1007802728"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1023/b:nere.0000026402.09466.54", 
      "https://app.dimensions.ai/details/publication/pub.1007802728"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T23:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000503.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1023%2FB%3ANERE.0000026402.09466.54"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1023/b:nere.0000026402.09466.54'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1023/b:nere.0000026402.09466.54'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1023/b:nere.0000026402.09466.54'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1023/b:nere.0000026402.09466.54'


 

This table displays all metadata directly associated to this object as RDF triples.

326 TRIPLES      21 PREDICATES      87 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1023/b:nere.0000026402.09466.54 schema:about N141e3bf8fbd74ba9a5075c6ee2533ab3
2 N265106d8378943688caf95c0f7b8882e
3 N2ddb66077539403facf6c5e710898daa
4 N345c6f0f0a3f4173acd1da982ddb69a6
5 N397ea540c3914120837fa024f767b57e
6 N3b2f5d4c8bba48bdb6d09d869b7bf3fe
7 N45149b70252f4dae86aa65dcd6687437
8 N52ca96a1faf949618c4266113eb819a3
9 N9140fc406e1c4f359b858b41a090fb0e
10 N95ef3fd5d0b24279a73178579c3fd51d
11 N995be4e5d17d400cbaca36d85a9b9106
12 N9b8c03baa98d4481b9073dc6034197a8
13 Nb068903fd94a4fc798dc69f41f26de34
14 Nbf96c4d0842b4a5c9fcebe2d6fa8ba57
15 Ne94f4ca2f72d48c789c173ea0cbf942b
16 Nfaa149fbbe2046f989478874966f9bba
17 Nfcf793d4d44441a2a2b5568ecc373d03
18 anzsrc-for:17
19 anzsrc-for:1701
20 schema:author Ncf1210544fd84df9b481c501e404e91a
21 schema:citation sg:pub.10.1007/bf00501182
22 sg:pub.10.1007/bf00652229
23 sg:pub.10.1007/bf00692778
24 sg:pub.10.1007/bf01243272
25 sg:pub.10.1007/bf01921910
26 sg:pub.10.1038/npp.1994.4
27 https://app.dimensions.ai/details/publication/pub.1077869157
28 https://app.dimensions.ai/details/publication/pub.1078691240
29 https://app.dimensions.ai/details/publication/pub.1078849190
30 https://app.dimensions.ai/details/publication/pub.1079337654
31 https://app.dimensions.ai/details/publication/pub.1083282226
32 https://doi.org/10.1001/archpsyc.1988.01800310072009
33 https://doi.org/10.1016/0006-8993(92)91079-t
34 https://doi.org/10.1016/0024-3205(95)00269-c
35 https://doi.org/10.1016/0024-3205(96)00452-3
36 https://doi.org/10.1016/0028-3908(88)90179-7
37 https://doi.org/10.1016/0028-3908(91)90075-m
38 https://doi.org/10.1016/0091-3057(83)90242-3
39 https://doi.org/10.1016/0091-3057(95)00177-x
40 https://doi.org/10.1016/0165-1781(96)02886-7
41 https://doi.org/10.1016/0169-328x(95)00097-c
42 https://doi.org/10.1016/0278-5846(92)90072-m
43 https://doi.org/10.1016/0920-9964(91)90056-w
44 https://doi.org/10.1016/0920-9964(94)90015-9
45 https://doi.org/10.1016/s0006-3223(03)00174-4
46 https://doi.org/10.1016/s0024-3205(01)01158-4
47 https://doi.org/10.1016/s0378-4347(00)81896-4
48 https://doi.org/10.1016/s1364-6613(98)01240-6
49 https://doi.org/10.1046/j.1471-4159.1998.70020708.x
50 https://doi.org/10.1055/s-2007-1017399
51 https://doi.org/10.1055/s-2007-979314
52 https://doi.org/10.1093/schbul/18.1.123
53 https://doi.org/10.1097/00002826-200007000-00004
54 https://doi.org/10.1097/00004714-199804000-00017
55 https://doi.org/10.1124/jpet.300.1.2
56 https://doi.org/10.1136/jnnp.53.10.915
57 https://doi.org/10.1139/y83-009
58 https://doi.org/10.1146/annurev.pharmtox.38.1.321
59 https://doi.org/10.1159/000118574
60 https://doi.org/10.1159/000119437
61 https://doi.org/10.1192/s0007125000291733
62 schema:datePublished 2004-07
63 schema:datePublishedReg 2004-07-01
64 schema:description The effects of acute lorazepam challenges on plasma (p) HVA, MHPG, and 5-HIAA, and their relationship to drug-induced cognitive and motor deficits and the apolipoprotein (APOE)-epsilon4 allele were examined. Eighteen healthy elderly (8 epsilon4 carriers) received placebo or acute oral lorazepam doses (0.5 mg or 1 mg) in random sequence, 1-week apart. Cognitive assessment and plasma levels of pHVA, pMHPG, and p5-HIAA were determined at baseline and at 1, 2.5, and 5 h postchallenge. There was no drug-to-placebo difference in monoamine levels and no consistent relationship between changes in monoamine levels and cognitive performance, regardless of epsilon4 status. However, the 1.0 mg dose increased p5-HIAA in epsilon4 carriers, whereas it caused a reduction in noncarriers. Higher baseline pMHPG and p5-HIAA levels were associated with better baseline memory. The epsilon4 allele may modulate the effect of lorazepam on p5-HIAA, but further studies are needed to confirm this finding and elucidate its possible significance.
65 schema:genre research_article
66 schema:inLanguage en
67 schema:isAccessibleForFree false
68 schema:isPartOf N2da0de27ac944d92a99eca7a23628957
69 Nd28b28647a6545be8cda29c5eed63dc3
70 sg:journal.1085962
71 schema:name Effects of Acute Lorazepam Administration on Aminergic Activity in Normal Elderly Subjects: Relationship to Performance Effects and Apolipoprotein Genotype
72 schema:pagination 1391-1398
73 schema:productId N1b81cb54a5044cc8be10bb45a91d7596
74 N20088b31ae09441396ec5dd15b699916
75 N379a3b1bfa8f447692e3dd2777b52402
76 N42b46962c714464196ed4ef3259bc841
77 Ncd6eb4f96b8940e898d1f71d9e060c53
78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007802728
79 https://doi.org/10.1023/b:nere.0000026402.09466.54
80 schema:sdDatePublished 2019-04-10T23:22
81 schema:sdLicense https://scigraph.springernature.com/explorer/license/
82 schema:sdPublisher N0363f5cab43e483d92e5a4a26dd49114
83 schema:url http://link.springer.com/10.1023%2FB%3ANERE.0000026402.09466.54
84 sgo:license sg:explorer/license/
85 sgo:sdDataset articles
86 rdf:type schema:ScholarlyArticle
87 N0363f5cab43e483d92e5a4a26dd49114 schema:name Springer Nature - SN SciGraph project
88 rdf:type schema:Organization
89 N0c33d8f2d7ce48aaa2b53a93ccbdf945 rdf:first sg:person.01002303570.20
90 rdf:rest N49124527a1964df7923c1f0535dc2c63
91 N141e3bf8fbd74ba9a5075c6ee2533ab3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Analysis of Variance
93 rdf:type schema:DefinedTerm
94 N1b81cb54a5044cc8be10bb45a91d7596 schema:name doi
95 schema:value 10.1023/b:nere.0000026402.09466.54
96 rdf:type schema:PropertyValue
97 N20088b31ae09441396ec5dd15b699916 schema:name nlm_unique_id
98 schema:value 7613461
99 rdf:type schema:PropertyValue
100 N265106d8378943688caf95c0f7b8882e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Middle Aged
102 rdf:type schema:DefinedTerm
103 N2da0de27ac944d92a99eca7a23628957 schema:issueNumber 7
104 rdf:type schema:PublicationIssue
105 N2ddb66077539403facf6c5e710898daa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Apolipoproteins
107 rdf:type schema:DefinedTerm
108 N345c6f0f0a3f4173acd1da982ddb69a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Lorazepam
110 rdf:type schema:DefinedTerm
111 N379a3b1bfa8f447692e3dd2777b52402 schema:name readcube_id
112 schema:value 252b0536aed7ec45d23afe5aa2fce56aa91ad441e644859ccc4ffc92c1af4ad9
113 rdf:type schema:PropertyValue
114 N397ea540c3914120837fa024f767b57e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Cognition Disorders
116 rdf:type schema:DefinedTerm
117 N3b2f5d4c8bba48bdb6d09d869b7bf3fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Genotype
119 rdf:type schema:DefinedTerm
120 N42b46962c714464196ed4ef3259bc841 schema:name dimensions_id
121 schema:value pub.1007802728
122 rdf:type schema:PropertyValue
123 N45149b70252f4dae86aa65dcd6687437 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Humans
125 rdf:type schema:DefinedTerm
126 N49124527a1964df7923c1f0535dc2c63 rdf:first sg:person.0753230673.42
127 rdf:rest Nb41c4efec5d848b182f6543de6155c66
128 N52ca96a1faf949618c4266113eb819a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Homovanillic Acid
130 rdf:type schema:DefinedTerm
131 N5355dad0a5514290b43c925595959b53 rdf:first sg:person.01353142263.05
132 rdf:rest N972dee7d10b949b688de4c250a689cb8
133 N9140fc406e1c4f359b858b41a090fb0e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Cognition
135 rdf:type schema:DefinedTerm
136 N91dcd17a5359455eb12e1b9a625e1f7b rdf:first sg:person.01151027326.07
137 rdf:rest N0c33d8f2d7ce48aaa2b53a93ccbdf945
138 N95ef3fd5d0b24279a73178579c3fd51d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Motor Activity
140 rdf:type schema:DefinedTerm
141 N972dee7d10b949b688de4c250a689cb8 rdf:first sg:person.01203017617.82
142 rdf:rest rdf:nil
143 N995be4e5d17d400cbaca36d85a9b9106 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Regression Analysis
145 rdf:type schema:DefinedTerm
146 N9b8c03baa98d4481b9073dc6034197a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Aged
148 rdf:type schema:DefinedTerm
149 Nb068903fd94a4fc798dc69f41f26de34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Apolipoproteins E
151 rdf:type schema:DefinedTerm
152 Nb41c4efec5d848b182f6543de6155c66 rdf:first sg:person.0742373640.18
153 rdf:rest N5355dad0a5514290b43c925595959b53
154 Nbf96c4d0842b4a5c9fcebe2d6fa8ba57 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Anti-Anxiety Agents
156 rdf:type schema:DefinedTerm
157 Ncd6eb4f96b8940e898d1f71d9e060c53 schema:name pubmed_id
158 schema:value 15202770
159 rdf:type schema:PropertyValue
160 Ncf1210544fd84df9b481c501e404e91a rdf:first sg:person.01202107722.21
161 rdf:rest Nf2481aa466b54f27be1e96ffd5c2d2d5
162 Nd28b28647a6545be8cda29c5eed63dc3 schema:volumeNumber 29
163 rdf:type schema:PublicationVolume
164 Nd8f32398e2d54695b7eb12b5df637d3e schema:name Cognitive Treatment Research Ltd., Reading, United Kingdom
165 rdf:type schema:Organization
166 Ne94f4ca2f72d48c789c173ea0cbf942b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Apolipoprotein E4
168 rdf:type schema:DefinedTerm
169 Nf2481aa466b54f27be1e96ffd5c2d2d5 rdf:first sg:person.0756255542.98
170 rdf:rest N91dcd17a5359455eb12e1b9a625e1f7b
171 Nfaa149fbbe2046f989478874966f9bba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Hydroxyindoleacetic Acid
173 rdf:type schema:DefinedTerm
174 Nfcf793d4d44441a2a2b5568ecc373d03 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Methoxyhydroxyphenylglycol
176 rdf:type schema:DefinedTerm
177 anzsrc-for:17 schema:inDefinedTermSet anzsrc-for:
178 schema:name Psychology and Cognitive Sciences
179 rdf:type schema:DefinedTerm
180 anzsrc-for:1701 schema:inDefinedTermSet anzsrc-for:
181 schema:name Psychology
182 rdf:type schema:DefinedTerm
183 sg:grant.2360787 http://pending.schema.org/fundedItem sg:pub.10.1023/b:nere.0000026402.09466.54
184 rdf:type schema:MonetaryGrant
185 sg:grant.2446922 http://pending.schema.org/fundedItem sg:pub.10.1023/b:nere.0000026402.09466.54
186 rdf:type schema:MonetaryGrant
187 sg:grant.2548624 http://pending.schema.org/fundedItem sg:pub.10.1023/b:nere.0000026402.09466.54
188 rdf:type schema:MonetaryGrant
189 sg:journal.1085962 schema:issn 0364-3190
190 1573-6903
191 schema:name Neurochemical Research
192 rdf:type schema:Periodical
193 sg:person.01002303570.20 schema:affiliation https://www.grid.ac/institutes/grid.250263.0
194 schema:familyName Sershen
195 schema:givenName Henry
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002303570.20
197 rdf:type schema:Person
198 sg:person.01151027326.07 schema:affiliation https://www.grid.ac/institutes/grid.250263.0
199 schema:familyName Hashim
200 schema:givenName Audrey
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01151027326.07
202 rdf:type schema:Person
203 sg:person.01202107722.21 schema:affiliation https://www.grid.ac/institutes/grid.137628.9
204 schema:familyName Pomara
205 schema:givenName Nunzio
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202107722.21
207 rdf:type schema:Person
208 sg:person.01203017617.82 schema:affiliation https://www.grid.ac/institutes/grid.250263.0
209 schema:familyName Lajtha
210 schema:givenName Abel
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203017617.82
212 rdf:type schema:Person
213 sg:person.01353142263.05 schema:affiliation https://www.grid.ac/institutes/grid.429997.8
214 schema:familyName Greenblatt
215 schema:givenName David J.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353142263.05
217 rdf:type schema:Person
218 sg:person.0742373640.18 schema:affiliation Nd8f32398e2d54695b7eb12b5df637d3e
219 schema:familyName Wesnes
220 schema:givenName Keith
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742373640.18
222 rdf:type schema:Person
223 sg:person.0753230673.42 schema:affiliation https://www.grid.ac/institutes/grid.137628.9
224 schema:familyName Sidtis
225 schema:givenName John J.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753230673.42
227 rdf:type schema:Person
228 sg:person.0756255542.98 schema:affiliation https://www.grid.ac/institutes/grid.137628.9
229 schema:familyName Willoughby
230 schema:givenName Lisa M.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756255542.98
232 rdf:type schema:Person
233 sg:pub.10.1007/bf00501182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001527684
234 https://doi.org/10.1007/bf00501182
235 rdf:type schema:CreativeWork
236 sg:pub.10.1007/bf00652229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053464066
237 https://doi.org/10.1007/bf00652229
238 rdf:type schema:CreativeWork
239 sg:pub.10.1007/bf00692778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034795847
240 https://doi.org/10.1007/bf00692778
241 rdf:type schema:CreativeWork
242 sg:pub.10.1007/bf01243272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052435140
243 https://doi.org/10.1007/bf01243272
244 rdf:type schema:CreativeWork
245 sg:pub.10.1007/bf01921910 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021974860
246 https://doi.org/10.1007/bf01921910
247 rdf:type schema:CreativeWork
248 sg:pub.10.1038/npp.1994.4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023420159
249 https://doi.org/10.1038/npp.1994.4
250 rdf:type schema:CreativeWork
251 https://app.dimensions.ai/details/publication/pub.1077869157 schema:CreativeWork
252 https://app.dimensions.ai/details/publication/pub.1078691240 schema:CreativeWork
253 https://app.dimensions.ai/details/publication/pub.1078849190 schema:CreativeWork
254 https://app.dimensions.ai/details/publication/pub.1079337654 schema:CreativeWork
255 https://app.dimensions.ai/details/publication/pub.1083282226 schema:CreativeWork
256 https://doi.org/10.1001/archpsyc.1988.01800310072009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022166240
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1016/0006-8993(92)91079-t schema:sameAs https://app.dimensions.ai/details/publication/pub.1040928496
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1016/0024-3205(95)00269-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1047849189
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1016/0024-3205(96)00452-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040480942
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/0028-3908(88)90179-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014882720
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1016/0028-3908(91)90075-m schema:sameAs https://app.dimensions.ai/details/publication/pub.1024518153
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1016/0091-3057(83)90242-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001894124
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1016/0091-3057(95)00177-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044857396
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1016/0165-1781(96)02886-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003367118
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1016/0169-328x(95)00097-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1006748224
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1016/0278-5846(92)90072-m schema:sameAs https://app.dimensions.ai/details/publication/pub.1052948072
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1016/0920-9964(91)90056-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1002686192
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1016/0920-9964(94)90015-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033241083
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1016/s0006-3223(03)00174-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034278160
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1016/s0024-3205(01)01158-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017045791
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/s0378-4347(00)81896-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018736821
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/s1364-6613(98)01240-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048645815
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1046/j.1471-4159.1998.70020708.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034559807
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1055/s-2007-1017399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057488964
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1055/s-2007-979314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057508750
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1093/schbul/18.1.123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026286993
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1097/00002826-200007000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032004484
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1097/00004714-199804000-00017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060188130
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1124/jpet.300.1.2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021034208
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1136/jnnp.53.10.915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007348276
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1139/y83-009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031694016
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1146/annurev.pharmtox.38.1.321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052864381
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1159/000118574 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017558193
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1159/000119437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049194203
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1192/s0007125000291733 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079234544
315 rdf:type schema:CreativeWork
316 https://www.grid.ac/institutes/grid.137628.9 schema:alternateName New York University
317 schema:name Department of Psychiatry, New York University School of Medicine, New York, New York
318 Geriatric Psychiatry Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York
319 rdf:type schema:Organization
320 https://www.grid.ac/institutes/grid.250263.0 schema:alternateName Nathan Kline Institute for Psychiatric Research
321 schema:name Center for Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York
322 Department of Psychiatry, New York University School of Medicine, New York, New York
323 rdf:type schema:Organization
324 https://www.grid.ac/institutes/grid.429997.8 schema:alternateName Tufts University
325 schema:name Department of Pharmacology, Tufts University, Boston, Massachusetts
326 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...