3D Fractal DNA Assembly from Coding, Geometry and Protection View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-08

AUTHORS

Alessandra Carbone, Chengde Mao, Pamela E. Constantinou, Baoquan Ding, Jens Kopatsch, William B. Sherman, Nadrian C. Seeman

ABSTRACT

We present DNA components whose 3D geometry and cohesive portions are compatible with a fractal 3D assembly. DNA parallelograms have been proposed in Carbone and Seeman [(2002b) Natural Computing 1: 469–480; (2003) Natural Computing 2: 133–151] as suitable building blocks for a 2D fractal assembly of the Sierpinski carpet. Here we use Mao 3D triangles, which are 3D geometrically trigonal molecules, to construct basic building blocks and we obtain a simplified version of the 2D assembly design. As in the previous 2D construction, we utilize the interplay of coding in the form of cohesive ends, geometrical complementarity and protection of potentially undesirable sites of reactivity. The schema we propose works for trigonal symmetries and the Mao triangle is one example of a possible DNA trigonal tile. More... »

PAGES

235-252

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/b:naco.0000036819.42166.1a

DOI

http://dx.doi.org/10.1023/b:naco.0000036819.42166.1a

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009779446


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