Ontology type: schema:ScholarlyArticle
2003-03
AUTHORST. Higashino, T. Miura, C. Miura, K. Yamauchi
ABSTRACTThe present study was carried out to investigate whether several sex steroid hormones are able to induce oogonial proliferation or initiation of meiotic division I in vitro. The results showed that 17β-estradiol (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (17α, 20β-DHP) were able to induce the DNA synthesis of ovarian germ cells. The percentage of oocytes in 17α, 20β-DHP treated fragments was significantly higher than that in the other treatments. From these results, we conclude that endogenous E2 and 17α, 20β-DHP synthesized in ovary play significant roles in the proliferation of oogonia and the initiation of meiotic division I in early oogenesis, respectively. More... »
PAGES343-344
http://scigraph.springernature.com/pub.10.1023/b:fish.0000030580.95994.77
DOIhttp://dx.doi.org/10.1023/b:fish.0000030580.95994.77
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