The Intravenous Xylitol Tolerance Test in Non-Lactating Cattle View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-12

AUTHORS

H. Mizutani, T. Sako, Y. Toyoda, H. Fukuda, N. Urumuhang, H. Koyama, H. Hirose

ABSTRACT

Xylitol is a five-carbon sugar alcohol that is often used for treatment of ketosis in dairy cattle in Japan. An intravenous xylitol tolerance test (IVXTT, 0.1 g/kg, bolus injection through the jugular vein) was performed in 4 non-lactating cows (n = 4) and the results were compared with those of an intravenous glucose tolerance test (IVGTT) performed under equivalent conditions. The serum xylitol concentration reached a peak value (41.4±9.0 mg/dl) at 5 min, and then rapidly decreased and almost disappeared within 2 h. The C0 for xylitol was 56.9±16.6 mg/dl and the t1/2was 8.5±0.9 min. The administration of xylitol appeared to cause similar secretion of insulin to that caused by glucose. There was also a reduction in the concentration of free fatty acids. It seems that xylitol has value for the treatment of ketosis. However, rapid administration of xylitol appeared to have an osmotic diuretic action and might be a cause of dehydration. More... »

PAGES

633-641

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1027372429555

DOI

http://dx.doi.org/10.1023/a:1027372429555

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028265545

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/14672452


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