Secure web book to store structural genomics research data View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-06

AUTHORS

Babu A. Manjasetty, Klaus Höppner, Uwe Mueller, Udo Heinemann

ABSTRACT

Recently established collaborative structural genomics programs aim at significantly accelerating the crystal structure analysis of proteins. These large-scale projects require efficient data management systems to ensure seamless collaboration between different groups of scientists working towards the same goal. Within the Berlin-based Protein Structure Factory, the synchrotron X-ray data collection and the subsequent crystal structure analysis tasks are located at BESSY, a third-generation synchrotron source. To organize file-based communication and data transfer at the BESSY site of the Protein Structure Factory, we have developed the web-based BCLIMS, the BESSY Crystallography Laboratory Information Management System. BCLIMS is a relational data management system which is powered by MySQL as the database engine and Apache HTTP as the web server. The database interface routines are written in Python programing language. The software is freely available to academic users. Here we describe the storage, retrieval and manipulation of laboratory information, mainly pertaining to the synchrotron X-ray diffraction experiments and the subsequent protein structure analysis, using BCLIMS. More... »

PAGES

121-127

References to SciGraph publications

  • 2001-02. Initial sequencing and analysis of the human genome in NATURE
  • 2000-11-01. Structural genomics in Europe: Slow start, strong finish? in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-11-01. Structural genomics projects in Japan in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2002-01. High-throughput crystallography for lead discovery in drug design in NATURE REVIEWS DRUG DISCOVERY
  • 2000-11-01. Structural genomics in North America in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-11-01. An overview of structural genomics in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-11-01. Automation of X-ray crystallography in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-11-01. The Protein Data Bank and the challenge of structural genomics in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1023/a:1026169519592

    DOI

    http://dx.doi.org/10.1023/a:1026169519592

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1003737206

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14649296


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