Transgene integration, organization and interaction in plants View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-05

AUTHORS

Ajay Kohli, Richard M. Twyman, Rita Abranches, Eva Wegel, Eva Stoger, Paul Christou

ABSTRACT

It has been appreciated for many years that the structure of a transgene locus can have a major influence on the level and stability of transgene expression. Until recently, however, it has been common practice to discard plant lines with poor or unstable expression levels in favor of those with practical uses. In the last few years, an increasing number of experiments have been carried out with the primary aim of characterizing transgene loci and studying the fundamental links between locus structure and expression. Cereals have been at the forefront of this research because molecular, genetic and cytogenetic analysis can be carried out in parallel to examine transgene loci in detail. This review discusses what is known about the structure and organization of transgene loci in cereals, both at the molecular and cytogenetic levels. In the latter case, important links are beginning to be revealed between higher order locus organization, nuclear architecture, chromatin structure and transgene expression. More... »

PAGES

247-258

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1023/a:1023941407376

    DOI

    http://dx.doi.org/10.1023/a:1023941407376

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1045439768

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12856933


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