Changes in Sensitivity of Leukemia P388 Cells to Oxidative Stress and Platidiam upon Tumor Growth View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-11

AUTHORS

V. V. Shaposhnikova, O. E. Orlova, A. A. Kudryavtsev, Yu. N. Korystov

ABSTRACT

We studied the effect of oxidative stress induced by hyperoxia, hydrogen peroxide, or menadione on leukemia P388 cells isolated from mice with early (4 days) and late (7 days) stages of tumor growth. Oxidative stress was shown to inhibit cell division and to induce apoptosis. The seven-day leukemia cells feature lower proliferative potential and higher sensitivity to oxidative stress and platidiam. More... »

PAGES

537-539

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1021707707052

DOI

http://dx.doi.org/10.1023/a:1021707707052

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039306962


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