Unexpected Low Efficacy of Stealth Liposomal Doxorubicin (Caelyx) and Vinorelbine in Metastatic Breast Cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-01

AUTHORS

Lorenza Rimassa, Carlo Carnaghi, Isabella Garassino, Piermario Salvini, Valeria Ginanni, Giuseppe Gullo, Emanuela Morenghi, Armando Santoro

ABSTRACT

In this phase II study, 23 patients with metastatic breast cancer were treated with a combination of Caelyx (40 mg/m2 on day 1) and vinorelbine (20 mg/m2 on days 1 and 8) every 4 weeks. According to the statistical design, enrollment was closed after the first stage due to the low response rate observed (four partial remissions, 12 stabilizations). Toxicity was acceptable, however, grade 3-4 neutropenia was not negligible. Our study does not support the development of this combination in advanced breast cancer. More... »

PAGES

185-188

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1021300719965

DOI

http://dx.doi.org/10.1023/a:1021300719965

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051148339

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12602917


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