Glutamatergic Transmission in the Rat Brain and Gravitational Stress View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-03

AUTHORS

T. A. Borisova, N. V. Krisanova

ABSTRACT

The effects of hypergravity stress on L-[14C]-glutamate release from synaptosomes obtained from the rat brain and on the kinetic parameters of high-affinity glutamate transport activity were investigated. We found that hypergravity stress affected only the Ca2+-dependent component of L-[14C]-glutamate release. It did not modify the transporter affinity, but the maximum rate of uptake dropped from 12.5 ± 3.2 to 5.6 ± 0.9 nmol/min/mg of protein (in control rats and in animals subjected to hypergravity, respectively). More... »

PAGES

118-119

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1020741503258

DOI

http://dx.doi.org/10.1023/a:1020741503258

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017536084

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/14983839


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