Uranium and other natural radionuclides in drinking water and risk of leukemia: a case–cohort study in Finland View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-11

AUTHORS

Anssi Auvinen, Päivi Kurttio, Juha Pekkanen, Eero Pukkala, Taina Ilus, Laina Salonen

ABSTRACT

Objective: We assessed the effect of natural uranium and other radionuclides in drinking water on risk of leukemia. Methods: The subjects (n = 144,627) in the base cohort had lived outside the municipal tapwater system during 1967–1980. A subcohort was formed as a stratified random sample of the base cohort and subjects using drinking water from drilled wells prior to 1981 were identified. A case–cohort design was used comparing exposure among cases with leukemia (n = 35) with a stratified random sample (n = 274) from the subcohort. Activity concentrations of uranium, radium-226, and radon in the drinking water were analyzed using radiochemical and alpha-spectrometric methods. Results: The median activity concentration of uranium in well water was 0.08 Bq/L for the leukemia cases and 0.06 Bq/L for the reference group, radon concentrations 80 and 130 Bq/L, respectively, and radium-226 concentrations 0.01 Bq/L for both groups. The hazard ratio of leukemia for uranium was 0.91 (95% confidence interval 0.73–1.13) per Bq/L, for radon 0.79 per Bq/L (95% CI 0.27–2.29), and for radium-226 0.80 (95% CI 0.46–1.39) per Bq/L. Conclusions: Our results do not indicate an increased risk of leukemia from ingestion of natural uranium or other radionuclides through drinking water at these exposure levels. More... »

PAGES

825-829

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1020647704999

DOI

http://dx.doi.org/10.1023/a:1020647704999

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004054541

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12462547


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