Chemical synthesis of Haemophilus influenzae glycopeptide conjugates View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-01

AUTHORS

Ali A Kandil, Neville Chan, Michel Klein, Pele Chong

ABSTRACT

A simple procedure for conjugating synthetic fragments of the capsular polysaccharide of Haemophilus influenzae type b, poly-3-beta-D-ribose-(1,1)-D-ribitol-5-phosphate (sPRP) to linear peptides is described. The procedure consists of (i) reacting the amino group of amino-heptyl sPRP with m-maleimidobenzoyl-N-hydroxysuccinimide (MBS) in phosphate buffer, pH 7.5; (ii) selectively coupling the MBS-modified sPRP to the sulfhydryl group of the cysteine residue of peptides containing functional T-helper cell epitope(s). The glycopeptide conjugates were purified by gel filtration chromatography, biochemically characterized, and elicited protective level of anti-PRP antibody responses in rabbits. More... »

PAGES

13-17

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1018500712733

DOI

http://dx.doi.org/10.1023/a:1018500712733

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032399629

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9076509


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacterial Outer Membrane Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromatography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromatography, High Pressure Liquid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Epitopes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycoproteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haemophilus Vaccines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haemophilus influenzae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peptide Fragments", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polysaccharides, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rabbits", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radioimmunoassay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "T-Lymphocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vaccines, Synthetic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Sanofi (Canada)", 
          "id": "https://www.grid.ac/institutes/grid.418933.4", 
          "name": [
            "Connaught Centre for Biotechnology Research, 1755 Steeles Avenue West, M2R 3T4, North York, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kandil", 
        "givenName": "Ali A", 
        "id": "sg:person.01273023072.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273023072.36"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Chan", 
        "givenName": "Neville", 
        "id": "sg:person.01101262167.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101262167.71"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Klein", 
        "givenName": "Michel", 
        "id": "sg:person.01121146450.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121146450.06"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Chong", 
        "givenName": "Pele", 
        "id": "sg:person.01111216321.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111216321.26"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0264-410x(94)00042-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001852972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.152.2.361", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007573800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/p19760000958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014333391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(05)81786-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016322598"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(95)70546-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016389206"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0264-410x(93)90160-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016923399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0264-410x(93)90160-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016923399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.155.6.1730", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018014052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(05)81186-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021541150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(83)91010-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035948946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archpedi.1994.02170010053011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038417603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1993.03500020080036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041533562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(95)70545-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044720172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-1992-21412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057394309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/infdis/153.3.448", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059699828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077329683", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077799500", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078909124", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082426954", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082462845", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082464092", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082666860", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082833441", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1997-01", 
    "datePublishedReg": "1997-01-01", 
    "description": "A simple procedure for conjugating synthetic fragments of the capsular polysaccharide of Haemophilus influenzae type b, poly-3-beta-D-ribose-(1,1)-D-ribitol-5-phosphate (sPRP) to linear peptides is described. The procedure consists of (i) reacting the amino group of amino-heptyl sPRP with m-maleimidobenzoyl-N-hydroxysuccinimide (MBS) in phosphate buffer, pH 7.5; (ii) selectively coupling the MBS-modified sPRP to the sulfhydryl group of the cysteine residue of peptides containing functional T-helper cell epitope(s). The glycopeptide conjugates were purified by gel filtration chromatography, biochemically characterized, and elicited protective level of anti-PRP antibody responses in rabbits.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1023/a:1018500712733", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1096094", 
        "issn": [
          "0969-3653", 
          "1573-4986"
        ], 
        "name": "Glycoconjugate Journal", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "14"
      }
    ], 
    "name": "Chemical synthesis of Haemophilus influenzae glycopeptide conjugates", 
    "pagination": "13-17", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9a58b03a45d2d3fb67670d6d8e6b6cfcc3e1b447672c0d013961abe03c08739e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9076509"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8603310"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1023/a:1018500712733"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1032399629"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1023/a:1018500712733", 
      "https://app.dimensions.ai/details/publication/pub.1032399629"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000506.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1023/A:1018500712733"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1023/a:1018500712733'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1023/a:1018500712733'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1023/a:1018500712733'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1023/a:1018500712733'


 

This table displays all metadata directly associated to this object as RDF triples.

217 TRIPLES      21 PREDICATES      69 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1023/a:1018500712733 schema:about N02c351fb931044fba14b2017a9815ea4
2 N27886e6125ac4602b20080ce95b61201
3 N2942ae6f42564f2aa21b02614be20d78
4 N2f558c1a876f47dcba17d078d0e6bf9c
5 N36ddff0e2cdf46739789d23b5cb4a94f
6 N59b7057831bd4c00b4996ec810a70d05
7 N63cfff33fb3447d5ba7fa895892df215
8 N6acdc7265f9e4935904853ae5dee7fbe
9 N7ab09962897e46fabbaceb12b47128ab
10 N89f727abb2e04431ac3c71ecf984fff0
11 N8cc57d003d1b4b7dadbc871c45b59ac0
12 Nae73f10cc8c548cf99c61a6cb2f04969
13 Nb4f26348da6e473fbda570db69b1a660
14 Nb8e05112cd534cce954079b836002468
15 Nbef57440a5944ca68e57f305ab0b49d2
16 Ne37ef05b4c6849a6b23c7002e16fc3c8
17 Ne69e4130199848d9a14785ed7766fa84
18 Ne741d1343eed45d9b6e4cad4f45bb182
19 anzsrc-for:06
20 anzsrc-for:0601
21 schema:author N937adc8fc89340899a51677c27555c7f
22 schema:citation https://app.dimensions.ai/details/publication/pub.1077329683
23 https://app.dimensions.ai/details/publication/pub.1077799500
24 https://app.dimensions.ai/details/publication/pub.1078909124
25 https://app.dimensions.ai/details/publication/pub.1082426954
26 https://app.dimensions.ai/details/publication/pub.1082462845
27 https://app.dimensions.ai/details/publication/pub.1082464092
28 https://app.dimensions.ai/details/publication/pub.1082666860
29 https://app.dimensions.ai/details/publication/pub.1082833441
30 https://doi.org/10.1001/archpedi.1994.02170010053011
31 https://doi.org/10.1001/jama.1993.03500020080036
32 https://doi.org/10.1016/0264-410x(93)90160-y
33 https://doi.org/10.1016/0264-410x(94)00042-l
34 https://doi.org/10.1016/s0022-3476(05)81186-2
35 https://doi.org/10.1016/s0022-3476(05)81786-x
36 https://doi.org/10.1016/s0022-3476(95)70545-7
37 https://doi.org/10.1016/s0022-3476(95)70546-5
38 https://doi.org/10.1016/s0076-6879(83)91010-8
39 https://doi.org/10.1039/p19760000958
40 https://doi.org/10.1055/s-1992-21412
41 https://doi.org/10.1084/jem.152.2.361
42 https://doi.org/10.1084/jem.155.6.1730
43 https://doi.org/10.1093/infdis/153.3.448
44 schema:datePublished 1997-01
45 schema:datePublishedReg 1997-01-01
46 schema:description A simple procedure for conjugating synthetic fragments of the capsular polysaccharide of Haemophilus influenzae type b, poly-3-beta-D-ribose-(1,1)-D-ribitol-5-phosphate (sPRP) to linear peptides is described. The procedure consists of (i) reacting the amino group of amino-heptyl sPRP with m-maleimidobenzoyl-N-hydroxysuccinimide (MBS) in phosphate buffer, pH 7.5; (ii) selectively coupling the MBS-modified sPRP to the sulfhydryl group of the cysteine residue of peptides containing functional T-helper cell epitope(s). The glycopeptide conjugates were purified by gel filtration chromatography, biochemically characterized, and elicited protective level of anti-PRP antibody responses in rabbits.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree false
50 schema:isPartOf N03f8358702c342118aa968106d030060
51 N56975f2f39fa49f19b942b542703f3f1
52 sg:journal.1096094
53 schema:name Chemical synthesis of Haemophilus influenzae glycopeptide conjugates
54 schema:pagination 13-17
55 schema:productId N0c36b4e586284f169a05001f24892306
56 N32ba116ba2044cddb787f7f9d1c34b96
57 N795a0332e36e43698116e33f8e84d42b
58 Nab52b8549e8043a08f660adebb3f163f
59 Nfbd7bf2322f54c088dae16cd00f4e295
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032399629
61 https://doi.org/10.1023/a:1018500712733
62 schema:sdDatePublished 2019-04-10T17:30
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N4686608de99245d1aa71af42c6976316
65 schema:url http://link.springer.com/10.1023/A:1018500712733
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N02c351fb931044fba14b2017a9815ea4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Amino Acid Sequence
71 rdf:type schema:DefinedTerm
72 N03f8358702c342118aa968106d030060 schema:issueNumber 1
73 rdf:type schema:PublicationIssue
74 N0c36b4e586284f169a05001f24892306 schema:name pubmed_id
75 schema:value 9076509
76 rdf:type schema:PropertyValue
77 N1242b8e396aa4588b57a2234e195dfe3 rdf:first sg:person.01111216321.26
78 rdf:rest rdf:nil
79 N27886e6125ac4602b20080ce95b61201 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Epitopes
81 rdf:type schema:DefinedTerm
82 N2942ae6f42564f2aa21b02614be20d78 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Radioimmunoassay
84 rdf:type schema:DefinedTerm
85 N2f558c1a876f47dcba17d078d0e6bf9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Peptide Fragments
87 rdf:type schema:DefinedTerm
88 N319b9fac5b5042db92760fb05448c3aa rdf:first sg:person.01121146450.06
89 rdf:rest N1242b8e396aa4588b57a2234e195dfe3
90 N32ba116ba2044cddb787f7f9d1c34b96 schema:name readcube_id
91 schema:value 9a58b03a45d2d3fb67670d6d8e6b6cfcc3e1b447672c0d013961abe03c08739e
92 rdf:type schema:PropertyValue
93 N36ddff0e2cdf46739789d23b5cb4a94f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Polysaccharides, Bacterial
95 rdf:type schema:DefinedTerm
96 N4686608de99245d1aa71af42c6976316 schema:name Springer Nature - SN SciGraph project
97 rdf:type schema:Organization
98 N56975f2f39fa49f19b942b542703f3f1 schema:volumeNumber 14
99 rdf:type schema:PublicationVolume
100 N59b7057831bd4c00b4996ec810a70d05 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name T-Lymphocytes
102 rdf:type schema:DefinedTerm
103 N63cfff33fb3447d5ba7fa895892df215 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Haemophilus influenzae
105 rdf:type schema:DefinedTerm
106 N6acdc7265f9e4935904853ae5dee7fbe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Bacterial Outer Membrane Proteins
108 rdf:type schema:DefinedTerm
109 N795a0332e36e43698116e33f8e84d42b schema:name doi
110 schema:value 10.1023/a:1018500712733
111 rdf:type schema:PropertyValue
112 N7ab09962897e46fabbaceb12b47128ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Chromatography
114 rdf:type schema:DefinedTerm
115 N7d2ec356283c48f1808ffe73b3db93f6 rdf:first sg:person.01101262167.71
116 rdf:rest N319b9fac5b5042db92760fb05448c3aa
117 N89f727abb2e04431ac3c71ecf984fff0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Chromatography, High Pressure Liquid
119 rdf:type schema:DefinedTerm
120 N8cc57d003d1b4b7dadbc871c45b59ac0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Animals
122 rdf:type schema:DefinedTerm
123 N937adc8fc89340899a51677c27555c7f rdf:first sg:person.01273023072.36
124 rdf:rest N7d2ec356283c48f1808ffe73b3db93f6
125 Nab52b8549e8043a08f660adebb3f163f schema:name nlm_unique_id
126 schema:value 8603310
127 rdf:type schema:PropertyValue
128 Nae73f10cc8c548cf99c61a6cb2f04969 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Molecular Sequence Data
130 rdf:type schema:DefinedTerm
131 Nb4f26348da6e473fbda570db69b1a660 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Haemophilus Vaccines
133 rdf:type schema:DefinedTerm
134 Nb8e05112cd534cce954079b836002468 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Vaccines, Synthetic
136 rdf:type schema:DefinedTerm
137 Nbef57440a5944ca68e57f305ab0b49d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Immunization
139 rdf:type schema:DefinedTerm
140 Ne37ef05b4c6849a6b23c7002e16fc3c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Rabbits
142 rdf:type schema:DefinedTerm
143 Ne69e4130199848d9a14785ed7766fa84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Antigens, Bacterial
145 rdf:type schema:DefinedTerm
146 Ne741d1343eed45d9b6e4cad4f45bb182 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Glycoproteins
148 rdf:type schema:DefinedTerm
149 Nfbd7bf2322f54c088dae16cd00f4e295 schema:name dimensions_id
150 schema:value pub.1032399629
151 rdf:type schema:PropertyValue
152 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
153 schema:name Biological Sciences
154 rdf:type schema:DefinedTerm
155 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
156 schema:name Biochemistry and Cell Biology
157 rdf:type schema:DefinedTerm
158 sg:journal.1096094 schema:issn 0969-3653
159 1573-4986
160 schema:name Glycoconjugate Journal
161 rdf:type schema:Periodical
162 sg:person.01101262167.71 schema:familyName Chan
163 schema:givenName Neville
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101262167.71
165 rdf:type schema:Person
166 sg:person.01111216321.26 schema:familyName Chong
167 schema:givenName Pele
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111216321.26
169 rdf:type schema:Person
170 sg:person.01121146450.06 schema:familyName Klein
171 schema:givenName Michel
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121146450.06
173 rdf:type schema:Person
174 sg:person.01273023072.36 schema:affiliation https://www.grid.ac/institutes/grid.418933.4
175 schema:familyName Kandil
176 schema:givenName Ali A
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273023072.36
178 rdf:type schema:Person
179 https://app.dimensions.ai/details/publication/pub.1077329683 schema:CreativeWork
180 https://app.dimensions.ai/details/publication/pub.1077799500 schema:CreativeWork
181 https://app.dimensions.ai/details/publication/pub.1078909124 schema:CreativeWork
182 https://app.dimensions.ai/details/publication/pub.1082426954 schema:CreativeWork
183 https://app.dimensions.ai/details/publication/pub.1082462845 schema:CreativeWork
184 https://app.dimensions.ai/details/publication/pub.1082464092 schema:CreativeWork
185 https://app.dimensions.ai/details/publication/pub.1082666860 schema:CreativeWork
186 https://app.dimensions.ai/details/publication/pub.1082833441 schema:CreativeWork
187 https://doi.org/10.1001/archpedi.1994.02170010053011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038417603
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1001/jama.1993.03500020080036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041533562
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/0264-410x(93)90160-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1016923399
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/0264-410x(94)00042-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1001852972
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/s0022-3476(05)81186-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021541150
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/s0022-3476(05)81786-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1016322598
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/s0022-3476(95)70545-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044720172
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/s0022-3476(95)70546-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016389206
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/s0076-6879(83)91010-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035948946
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1039/p19760000958 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014333391
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1055/s-1992-21412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057394309
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1084/jem.152.2.361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007573800
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1084/jem.155.6.1730 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018014052
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1093/infdis/153.3.448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059699828
214 rdf:type schema:CreativeWork
215 https://www.grid.ac/institutes/grid.418933.4 schema:alternateName Sanofi (Canada)
216 schema:name Connaught Centre for Biotechnology Research, 1755 Steeles Avenue West, M2R 3T4, North York, Ontario, Canada
217 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...