Bioavailable Testosterone as a Correlate of Cognition, Psychological Status, Quality of Life, and Sexual Function in Aging Males: Implications for ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-06

AUTHORS

Paul J. Perry, Brian C. Lund, Stephan Arndt, Timothy Holman, Kristine A. Bever-Stille, Jane Paulsen, Laurence M. Demers

ABSTRACT

Andropause is a syndrome described in aging males, is composed of a constellation of physical, sexual, and emotional symptoms, and is thought to be related to declining concentrations of serum testosterone. Numerous studies of testosterone replacement therapy in elderly hypogonadal males have documented the physical benefits of such treatment, but have failed to assess cognition, psychological functioning, and quality of life. Male outpatients greater or equal to 55 years of age completed cognitive, psychological, sexual, and quality of life assessments. A serum sample was provided for bioavailable testosterone assay. The associations between bioavailable testosterone concentrations and neuropsychological testing were assessed using Spearman rank correlation. Overall, bioavailable testosterone was not an important determinant of cognitive, psychological, or sexual functioning or of quality of life. The implications for future studies involving testosterone replacement therapy are discussed. More... »

PAGES

75-80

References to SciGraph publications

  • 1992-03. Assessing impairment in patients with panic disorder: the Sheehan Disability Scale in SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
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