Spectroscopic Studies of α,γ-Disubstituted Trimethine Cyanine: New Fluorescent Dye for Nucleic Acids View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-03

AUTHORS

I. V. Valyukh, V. B. Kovalska, Y. L. Slominskii, S. M. Yarmoluk

ABSTRACT

Spectral properties of 3-methyl-2-3-[3-methyl-1,3-benzothiazolo-2(3H)-ylidene]-1,4-cylopentadien-1-yl-1,3-benzothiazolo-3-ium tosylate (Cyan-Cpentd) in a free state and in the complexes with nucleic acids and synthetic polynucleotides have been investigated by absorption and fluorescence spectroscopy. Significant fluorescence intensity enhancement of dye-nucleic acids complexes is observed. For the first time Cyan-Cpentd is proposed as a new probe for nucleic acid detection. Binding mechanism of Cyan-Cpentd is discussed in view of the NA-ligand interaction models. More... »

PAGES

105-107

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1015327707062

DOI

http://dx.doi.org/10.1023/a:1015327707062

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017283051


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